Modeling effects of strain-modulated membrane capacitance and conductance of K+ inward rectifier on conduction velocity in cardiac tissue

Computers in Cardiology

Volumn 36, Issue , 2009, Pages 381-384

  McNary, Thomas G ^a,b   Sachse, F B ^a,b  

^a UNIVERSITY OF UTAH   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIAC MYOCYTES; CARDIAC TISSUES; CELLULAR ELECTROPHYSIOLOGY; COMPUTATIONAL SIMULATION; CONDUCTION VELOCITY; DEFAULT VALUES; INWARD-RECTIFYING; ION CHANNEL; MECHANICAL DEFORMATION; MEMBRANE PROPERTIES; MODELING EFFECTS; STRAIN MODULATION;

CARDIOLOGY; COMPUTER SIMULATION; DISTILLATION; MATHEMATICAL MODELS;

CAPACITANCE;

EID: 77952678410     PISSN: 02766574     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (19)

1. Zabel M, Portnoy S, Franz MR. Effect of sustained load on dispersion of ventricluar repolarization and conduction time in the isolated intact rabbit heart. J Cardiovasc Electrophysiol January 1996;7:9-16. (Pubitemid 126426334)
2. Reiter MJ, Landers M, Zetelaki Z, Kirchhof CJH, Allessie MA. Electrophysiological effects of accute dilation in the isolated rabbit heart. Circulation 1997;96:4050-4056.
3. Sung D, Mills RW, Schettler J, Narayan SM, Omens JH, McCulloch AD. Ventricular filling slows epicardial conduction and increases action potential duration in an optical mapping study of the isolated rabbit heart. J Cardiovasc Electrophysiol Jul 2003;14(7):739-749
4. Eijsbouts SCM, Majidi M, van Zandvoort M, Allessie MA. Effects of acute atrial dilation on heterogeneity in conduction in the isolated rabbit heart. J Cardiovasc Electrophysiol Mar. 2003;14:269-278. (Pubitemid 36444468)
5. McNary TG, Sohn K, Taccardi B, Sachse FB. Experimental and computational studies of strain-conduction velocity relationships in cardiac tissue. Prog Biophys Mol Biol 2008; 97:383-400.
6. Zabel M, Franz MR. Mechanical triggers and facilitators of cardiac excitation and arrhythmias. In Kohl P, Sachs F, Franz MR (eds.), Cardiac Mechano-Electric Feedback and Arrhythmias. Elsevier Saunders, 2005; 119-126
7. Taggart P, Sutton P. Load dependence of ventricular repolarization. In Koh P, Sachs F, Franz MR (eds.), Cardiac Mechano-Electric Feedback and Arrhythmias. Elsevier Saunders, 2005; 191-197.
8. Taggart P, Sutton P. Termination of arrhythmias by hemodynamic unloading. In Kohl P, Sachs F, Franz MR (eds.), Cardiac Mechano-Electric Feedback and Arrhythmias. Elsevier Saunders, 2005; 315-320.
9. Ruknudin A, Sachs F, Bustamante JO. Stretch-activated ion channels in tissue-cultured chick heart. Am J Physiol Heart Circ Physiol 1993;264(33):H960-972.
10. Zeng T, Bett GCL, Sachs F. Stretch-activated whole cell currents in adult rat cardiac myocytes. Am J Physiol 2000; 278:H548-H557.
11. Belus A, White E. Streptomycin and intracellular calcium modulate the response of single guinea-pig ventricular myocytes to axial stretch. J Physiol Jan 2003;15(546):501-509 (Pubitemid 36175985)
12. Dyachenko V, Husse B, Rueckschloss U, Isenberg G. Mechanical deformation of ventricular myocytes modulates both trpc6 and kir2.3 channels. Cell Calcium 2008;.
13. c in ventricular myocytes. Prog Biophys Mol Biol 2003;82:43-56.
14. Mills RW, Narayan SM, McCulloch AD. Mechanisms of conduction slowing during myocardial stretch by ventricular volume loading in the rabbit. Am J Physiol Circ Physiol 2008;295:H1270-H1278.
15. Kohl P, Cooper PJ, Holloway H. Effects of acute ventricular volume manipulation on in situ cardiomyocyte cell membrane configuration. Prog Biophys Mol Biol 2003;82(1-3):222-227.
16. Henriquez CS. Simulating the electrical behaviour of cardiac tissue using the bidomain model. Crit Rev Biomed Engin 1993;21(1):1-77.
17. Patel AJ, Honoré E. Potassium-selective cardiac mechanosensitive ion channels. In Kohl P, Sachs F, Franz MR (eds.), Cardiac Mechano-Electric Feedback and Arrhythmias. Elsevier Saunders, 2005; 11-20.
18. Ks, and length- and tension-dependend processes. Can J Cardiol Jan. 1998;14(1):123-134.
19. Healy SN, McCulloch AD. An ionic model of stretch-activated and stretch-modulated currents in rabbit ventricular myocytes. Europace 2005;7(S128-S134).