Inhibition of EGFR pathway signaling and the metastatic potential of breast cancer cells by PA-MSHA mediated by type 1 fimbriae via a mannose-dependent manner

Oncogene

Volumn 29, Issue 20, 2010, Pages 2996-3009

  Liu, Z B ^a   Hou, Y F ^a   Zhu, J ^b   Hu, D L ^b   Jin, W ^a   Ou, Z L ^a   Di, G H ^a   Wu, J ^a   Shen, Z Z ^a   Shao, Z M ^a  

^a FUDAN UNIVERSITY   (China)

^b Radiopharmaceutical Lab   (China)

Author keywords

Breast tumor; EGFR; Mannose; PA MSHA vaccine; Sugar binding

Indexed keywords

CASPASE; EPIDERMAL GROWTH FACTOR RECEPTOR; FIMBRIA PROTEIN; HEMAGGLUTININ; MANNOSE; PSEUDOMONAS AERUGINOSA MANNOSE MANNOSE SENSITIVE HEMAGGLUTININ; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BREAST CANCER; CARCINOGENESIS; CELL CYCLE ARREST; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; FEMALE; HUMAN; HUMAN CELL; IC 50; LUNG METASTASIS; METASTASIS; MICROMETASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RECEPTOR DOWN REGULATION; SURFACE PROPERTY; TUMOR GROWTH; TUMOR XENOGRAFT;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; BREAST NEOPLASMS; CELL ADHESION; CELL LINE, TUMOR; CELL PROLIFERATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FIMBRIAE, BACTERIAL; FLOW CYTOMETRY; HEMAGGLUTININS; HUMANS; LUNG NEOPLASMS; MANNOSE; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASM TRANSPLANTATION; PSEUDOMONAS AERUGINOSA; RECEPTOR, EPIDERMAL GROWTH FACTOR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

MUS; PSEUDOMONAS AERUGINOSA;

EID: 77952669722     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2010.70     Document Type: Article

References (32)

1. Capdevila J, Elez E, Macarulla T, Ramos FJ, Ruiz-Echarri M, Tabernero J. (2009). Anti-epidermal growth factor receptor monoclonal antibodies in cancer treatment. Cancer Treat Rev 35: 354-363.
2. Duguid JP. (1968). The function of bacterial fimbriae. Arch Immunol Ther Exp (Warsz) 16: 173-188.
3. Duncan MJ, Mann EL, Cohen MS, Ofek I, Sharon N, Abraham SN. (2005). The distinct binding specificities exhibited by enterobacterial type 1 fimbriae are determined by their fimbrial shafts. J Biol Chem 280: 37707-37716. (Pubitemid 41642379)
4. Eshdat Y, Sharon N. (1984). Recognitory bacterial surface lectins which mediate its mannose-specific adherence to eukaryotic cells. Biol Cell 51: 259-266. (Pubitemid 15218623)
5. Gibson S, Tu S, Oyer R, Anderson SM, Johnson GL. (1999). Epidermal growth factor protects epithelial cells against Fas-induced apoptosis requirement for Akt activation. J Biol Chem 274: 17612-17618. (Pubitemid 129519112)
6. Harper M, Turvey A, Bramley AJ. (1978). Adhesion of fimbriate Escherichia coli to bovine mammary-gland epithelial cells in vitro. J Med Microbiol 11: 117-123. (Pubitemid 8350531)
7. Helenius A, Aebi M. (2001). Intracellular functions of N-linked glycans. Science 291: 2364-2369. (Pubitemid 32231791)
8. Hoadley KA, Weigman VJ, Fan C, Sawyer LR, He X, Troester MA et al. (2007). EGFR associated expression profiles vary with breast tumor subtype. BMC Genomics 8: 258. (Pubitemid 47559211)
9. Jain RK, Forbes NS. (2001). Can engineered bacteria help control cancer? Proc Natl Acad Sci USA 98: 14748-14750. (Pubitemid 34013912)
10. Johns TG, Mellman I, Cartwright GA, Ritter G, Old LJ, Burgess AW et al. (2005). The antitumor monoclonal antibody 806 recognizes a high-mannose form of the EGF receptor that reaches the cell surface when cells over-express the receptor. FASEB J 19: 780-782. (Pubitemid 40617382)
11. Kang CS, Zhang ZY, Jia ZF, Wang GX, Qiu MZ, Zhou HX et al. (2006). Suppression of EGFR expression by antisense or small interference RNA inhibits U251 glioma cell growth in vitro and in vivo. Cancer Gene Ther 13: 530-538.
12. Karlsson KA. (2001). Pathogen-host protein-carbohydrate interactions as the basis of important infections. Adv Exp Med Biol 491: 431-443.
13. Kawashima N, Yoon SJ, Itoh K, Nakayama K. (2009). Tyrosine kinase activity of epidermal growth factor receptor is regulated by GM3 binding through carbohydrate to carbohydrate interactions. J Biol Chem 284: 6147-6155.
14. King SS, Young DA, Nequin LG, Carnevale EM. (2000). Use of specific sugars to inhibit bacterial adherence to equine endometrium in vitro. Am J Vet Res 61: 446-449.
15. Klumpp DJ, Rycyk MT, Chen MC, Thumbikat P, Sengupta S, Schaeffer AJ. (2006). Uropathogenic Escherichia coli induces extrinsic and intrinsic cascades to initiate urothelial apoptosis. Infect Immun 74: 5106-5113. (Pubitemid 44300428)
16. Korhonen TK, Leffler H, Svanborg Eden C. (1981). Binding specificity of piliated strains of Escherichia coli and Salmonella typhimurium to epithelial cells, saccharomyces cerevisiae cells, and erythrocytes. Infect Immun 32: 796-804. (Pubitemid 11101716)
17. Korhonen TK, Lounatmaa K, Ranta H, Kuusi N. (1980). Characterization of type 1 pili of Salmonella typhimurium LT2. J Bacteriol 144: 800-805. (Pubitemid 11164201)
18. Lage A, Crombet T, Gonzalez G. (2003). Targeting epidermal growth factor receptor signaling: early results and future trends in oncology. Ann Med 35: 327-336. (Pubitemid 37013673)
19. Liu B, Cheng Y, Bian HJ, Bao JK. (2009a). Molecular mechanisms of Polygonatum cyrtonema lectin-induced apoptosis and autophagy in cancer cells. Autophagy 5: 253-255.
20. Liu B, Min MW, Bao JK. (2009b). Induction of apoptosis by Concanavalin A and its molecular mechanisms in cancer cells. Autophagy 5: 432-433.
21. Liu ZB, Hou YF, Di GH, Wu J, Shen ZZ, Shao ZM. (2009c). PA-MSHA inhibits proliferation and induces apoptosis through the up-regulation and activation of caspases in the human breast cancer cell lines. J Cell Biochem 108: 195-206.
22. McEwan NA, Reme CA, Gatto H, Nuttall TJ. (2008). Monosacchar-ide inhibition of adherence by Pseudomonas aeruginosa to canine corneocytes. Vet Dermatol 19: 221-225.
23. Mulvey MA, Lopez-Boado YS, Wilson CL, Roth R, Parks WC, Heuser J et al. (1998). Induction and evasion of host defenses by type 1-piliated uropathogenic Escherichia coli. Science 282: 1494-1497. (Pubitemid 28538612)
24. Ofek I, Beachey EH. (1978). Mannose binding and epithelial cell adherence of Escherichia coli. Infect Immun 22: 247-254. (Pubitemid 9040724)
25. Schaerli P, Jaggi R. (1998). EGF-induced programmed cell death of human mammary carcinoma MDA-MB-468 cells is preceded by activation AP-1. Cell Mol Life Sci 54: 129-138. (Pubitemid 28134857)
26. Schilling JD, Mulvey MA, Hultgren SJ. (2001). Structure and function of Escherichia coli type 1 pili: new insight into the pathogenesis of urinary tract infections. J Infect Dis 183(Suppl 1): S36-S40.
27. Sharon N. (1987). Bacterial lectins, cell-cell recognition and infectious disease. FEBS Lett 217: 145-157. (Pubitemid 17086739)
28. Sharon N. (2006). Carbohydrates as future anti-adhesion drugs for infectious diseases. Biochim Biophys Acta 1760: 527-537.
29. Stepinska M, Trafny EA. (1995). Modulation of Pseudomonas aeruginosa adherence to collagen type I and type II by carbohydrates. FEMS Immunol Med Microbiol 12: 187-194.
30. Wang JS, Wang FB, Zhang QG, Shen ZZ, Shao ZM. (2008). Enhanced expression of Rab27A gene by breast cancer cells promoting invasiveness and the metastasis potential by secretion of insulin-like growth factor-II. Mol Cancer Res 6: 372-382.
31. Wiest I, Seliger C, Walzel H, Friese K, Jeschke U. (2003). Int Inst Anticancer Research: Hamburg, Germany. pp 1575-1580.
32. Zhang H, Berezov A, Wang Q, Zhang G, Drebin J, Murali R et al. (2007). ErbB receptors: from oncogenes to targeted cancer therapies. J Clin Invest 117: 2051-2058. (Pubitemid 47224766)