메뉴 건너뛰기




Volumn 119, Issue 1-3, 2010, Pages 160-163

Do atypical antipsychotic drugs reduce the risk of ischemic heart disease and mortality? Possible role of 5-HT2A receptor blockade

Author keywords

Adverse effects; Antipsychotics; Coronary artery disease; Long QT syndrome; Metabolic syndrome; Mortality; Schizophrenia

Indexed keywords

ATYPICAL ANTIPSYCHOTIC AGENT; CLOZAPINE; HISTAMINE H1 RECEPTOR ANTAGONIST; N [2 [4 (5H DIBENZO[A,D]CYCLOHEPTEN 5 YLIDENE)PIPERIDINO]ETHYL] 1 FORMYLISONIPECOTAMIDE; OLANZAPINE; PERPHENAZINE; QUETIAPINE; RISPERIDONE; SEROTONIN 2A ANTAGONIST; SEROTONIN 2A RECEPTOR; SEROTONIN 2B RECEPTOR; THIORIDAZINE; UNCLASSIFIED DRUG; ZIPRASIDONE;

EID: 77952668659     PISSN: 09209964     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.schres.2009.12.005     Document Type: Article
Times cited : (10)

References (43)
  • 1
    • 34547469943 scopus 로고    scopus 로고
    • Pharmacogenetics and pharmacogenomics of schizophrenia: a review of last decade of research
    • Arranz M.J., de Leon J. Pharmacogenetics and pharmacogenomics of schizophrenia: a review of last decade of research. Mol. Psychiatry 2007, 12:707-747.
    • (2007) Mol. Psychiatry , vol.12 , pp. 707-747
    • Arranz, M.J.1    de Leon, J.2
  • 3
    • 40949134281 scopus 로고    scopus 로고
    • Beyond the "hype" on the association between metabolic syndrome and atypical antipsychotics: the confounding effects of cohort, typical antipsychotics, severe mental illness, and co-morbid substance use (editorial)
    • de Leon J. Beyond the "hype" on the association between metabolic syndrome and atypical antipsychotics: the confounding effects of cohort, typical antipsychotics, severe mental illness, and co-morbid substance use (editorial). J. Clin. Psychopharmacol. 2008, 28:125-131.
    • (2008) J. Clin. Psychopharmacol. , vol.28 , pp. 125-131
    • de Leon, J.1
  • 4
    • 20444463577 scopus 로고    scopus 로고
    • A meta-analysis of worldwide studies demonstrates an association between schizophrenia and tobacco smoking behaviors
    • de Leon J., Diaz F.J. A meta-analysis of worldwide studies demonstrates an association between schizophrenia and tobacco smoking behaviors. Schizophr. Res. 2005, 76:135-157.
    • (2005) Schizophr. Res. , vol.76 , pp. 135-157
    • de Leon, J.1    Diaz, F.J.2
  • 5
    • 34848889545 scopus 로고    scopus 로고
    • Planning for the optimal design of studies to personalize antipsychotic prescriptions in the post-CATIE era: the clinical and pharmacoepidemiological data suggest that pursuing the pharmacogenetics of metabolic syndrome complications (hypertension, diabetes mellitus and hyperlipidemia) may be a reasonable strategy
    • de Leon J., Diaz F.J. Planning for the optimal design of studies to personalize antipsychotic prescriptions in the post-CATIE era: the clinical and pharmacoepidemiological data suggest that pursuing the pharmacogenetics of metabolic syndrome complications (hypertension, diabetes mellitus and hyperlipidemia) may be a reasonable strategy. Schizophr. Res. 2007, 96:185-197.
    • (2007) Schizophr. Res. , vol.96 , pp. 185-197
    • de Leon, J.1    Diaz, F.J.2
  • 7
    • 33747159598 scopus 로고    scopus 로고
    • Does smoking reduce akathisia?: Testing a narrow version of the self-medication hypothesis
    • de Leon J., Diaz F.J., Aguilar M.C., Jurado D., Gurpegui M. Does smoking reduce akathisia?: Testing a narrow version of the self-medication hypothesis. Schizophr. Res. 2006, 86:256-268.
    • (2006) Schizophr. Res. , vol.86 , pp. 256-268
    • de Leon, J.1    Diaz, F.J.2    Aguilar, M.C.3    Jurado, D.4    Gurpegui, M.5
  • 8
    • 36448929146 scopus 로고    scopus 로고
    • Epidemiology of comorbid tobacco use and schizophrenia: thinking about risks and protective factors
    • de Leon J., Gurpegui M., Diaz F.J. Epidemiology of comorbid tobacco use and schizophrenia: thinking about risks and protective factors. J. Dual Diag. 2007, 3:9-25.
    • (2007) J. Dual Diag. , vol.3 , pp. 9-25
    • de Leon, J.1    Gurpegui, M.2    Diaz, F.J.3
  • 9
    • 43449101550 scopus 로고    scopus 로고
    • A preliminary attempt to personalize risperidone dosing using drug-drug interactions and genetics: part I
    • de Leon J., Sandson N.B., Cozza K.L. A preliminary attempt to personalize risperidone dosing using drug-drug interactions and genetics: part I. Psychosomatics 2008, 49:258-270.
    • (2008) Psychosomatics , vol.49 , pp. 258-270
    • de Leon, J.1    Sandson, N.B.2    Cozza, K.L.3
  • 10
    • 46149124547 scopus 로고    scopus 로고
    • A preliminary attempt to personalize risperidone dosing using drug-drug interactions and genetics: part II
    • de Leon J., Sandson N.B., Cozza K.L. A preliminary attempt to personalize risperidone dosing using drug-drug interactions and genetics: part II. Psychosomatics 2008, 49:347-361.
    • (2008) Psychosomatics , vol.49 , pp. 347-361
    • de Leon, J.1    Sandson, N.B.2    Cozza, K.L.3
  • 11
    • 71949126216 scopus 로고    scopus 로고
    • Acetyl-coenzyme A carboxylase ? gene variations may be associated with the direct effects of some antipsychotics on triglyceride levels
    • Diaz F.J., Meary A., Arranz M.J., Ruaño G., Windemuth A., de Leon J. Acetyl-coenzyme A carboxylase ? gene variations may be associated with the direct effects of some antipsychotics on triglyceride levels. Schizophr. Res. 2009, 115:136-140.
    • (2009) Schizophr. Res. , vol.115 , pp. 136-140
    • Diaz, F.J.1    Meary, A.2    Arranz, M.J.3    Ruaño, G.4    Windemuth, A.5    de Leon, J.6
  • 12
    • 77952669643 scopus 로고    scopus 로고
    • EMEA (European Medicines Agency), 2008. CHMP assessment report on conventional antipsychotics (EMEA/CHMP/590557/2008).
    • EMEA (European Medicines Agency), 2008. CHMP assessment report on conventional antipsychotics (EMEA/CHMP/590557/2008). http://www.emea.europa.eu/pdfs/human/opiniongen/Conventional_%20Antipsychotics_Article5.3-Appendix1-CHMPAR.pdf.
  • 18
    • 0034110915 scopus 로고    scopus 로고
    • AT-1015, a novel serotonin (5-HT)2 receptor antagonist, blocks vascular and platelet 5-HT2A receptors and prevents the laurate-induced peripheral vascular lesion in rats
    • Kihara H., Hirose K., Koganei H., Sasaki N., Yamamoto H., Kimura A., Nishimori T., Shoji M., Yoshimoto R. AT-1015, a novel serotonin (5-HT)2 receptor antagonist, blocks vascular and platelet 5-HT2A receptors and prevents the laurate-induced peripheral vascular lesion in rats. J. Cardiovasc. Pharmacol. 2000, 35:523-530.
    • (2000) J. Cardiovasc. Pharmacol. , vol.35 , pp. 523-530
    • Kihara, H.1    Hirose, K.2    Koganei, H.3    Sasaki, N.4    Yamamoto, H.5    Kimura, A.6    Nishimori, T.7    Shoji, M.8    Yoshimoto, R.9
  • 21
    • 77952670081 scopus 로고    scopus 로고
    • APA guidance on the use of antipsychotic drugs and cardiac sudden death prepared by for the APA Council on Research.
    • Lieberman, J.A., Merrill, D., Parameswaran, S. (2009). APA guidance on the use of antipsychotic drugs and cardiac sudden death prepared by for the APA Council on Research. http://www.omh.state.ny.us/omhweb/advisories/adult_antipsychotic_use_attachement.html.
    • (2009)
    • Lieberman, J.A.1    Merrill, D.2    Parameswaran, S.3
  • 22
    • 33644684681 scopus 로고    scopus 로고
    • Receptor occupancy-based analysis of the contributions of various receptors to antipsychotic-induced weight gain and diabetes mellitus
    • Matsui-Sakata A., Ohtani H., Sawada Y. Receptor occupancy-based analysis of the contributions of various receptors to antipsychotic-induced weight gain and diabetes mellitus. Drug Metab. Pharmacokinet. 2005, 20:368-378.
    • (2005) Drug Metab. Pharmacokinet. , vol.20 , pp. 368-378
    • Matsui-Sakata, A.1    Ohtani, H.2    Sawada, Y.3
  • 23
    • 3142769794 scopus 로고    scopus 로고
    • The effects of antipsychotic therapy on serum lipids: a comprehensive review
    • Meyer J.M., Koro C.E. The effects of antipsychotic therapy on serum lipids: a comprehensive review. Schizophr. Res. 2004, 70:1-17.
    • (2004) Schizophr. Res. , vol.70 , pp. 1-17
    • Meyer, J.M.1    Koro, C.E.2
  • 24
    • 57449083235 scopus 로고    scopus 로고
    • The metabolic syndrome and schizophrenia
    • Meyer J.M., Stahl S.M. The metabolic syndrome and schizophrenia. Acta Psychiatr. Scand. 2009, 119:4-14.
    • (2009) Acta Psychiatr. Scand. , vol.119 , pp. 4-14
    • Meyer, J.M.1    Stahl, S.M.2
  • 27
    • 0036773659 scopus 로고    scopus 로고
    • Neuroleptics and mortality in schizophrenia: prospective analysis of deaths in a French cohort of schizophrenic patients
    • Montout C., Casadebaig F., Lagnaoui R., Verdoux H., Philippe A., Begaud B., Moore N. Neuroleptics and mortality in schizophrenia: prospective analysis of deaths in a French cohort of schizophrenic patients. Schizophr. Res. 2002, 57:147-156.
    • (2002) Schizophr. Res. , vol.57 , pp. 147-156
    • Montout, C.1    Casadebaig, F.2    Lagnaoui, R.3    Verdoux, H.4    Philippe, A.5    Begaud, B.6    Moore, N.7
  • 28
  • 29
    • 6944222950 scopus 로고    scopus 로고
    • Functions of 5-HT2A receptor and its antagonists in the cardiovascular system
    • Nagatomo T., Rashid M., Abul Muntasir H., Komiyama T. Functions of 5-HT2A receptor and its antagonists in the cardiovascular system. Pharmacol. Ther. 2004, 104:59-81.
    • (2004) Pharmacol. Ther. , vol.104 , pp. 59-81
    • Nagatomo, T.1    Rashid, M.2    Abul Muntasir, H.3    Komiyama, T.4
  • 30
    • 33846987937 scopus 로고    scopus 로고
    • The roles of efficacy, safety, and tolerability in antipsychotic effectiveness: practical implications of the CATIE schizophrenia trial
    • Nasrallah H.A. The roles of efficacy, safety, and tolerability in antipsychotic effectiveness: practical implications of the CATIE schizophrenia trial. J. Clin. Psychiatry 2007, 68(Suppl 1):5-11.
    • (2007) J. Clin. Psychiatry , vol.68 , Issue.SUPPL. 1 , pp. 5-11
    • Nasrallah, H.A.1
  • 31
    • 37249034101 scopus 로고    scopus 로고
    • Atypical antipsychotic-induced metabolic side effects: insights from receptor-binding profiles
    • Nasrallah H.A. Atypical antipsychotic-induced metabolic side effects: insights from receptor-binding profiles. Mol. Psychiatry 2008, 13:27-35.
    • (2008) Mol. Psychiatry , vol.13 , pp. 27-35
    • Nasrallah, H.A.1
  • 32
    • 33747180826 scopus 로고    scopus 로고
    • Low rates of treatment for hypertension, dyslipidemia and diabetes in schizophrenia: data from the CATIE schizophrenia trial sample at baseline
    • Nasrallah H.A., Meyer J.M., Goff D.C., McEvoy J.P., Davis S.M., Stroup T.S., Lieberman J.A. Low rates of treatment for hypertension, dyslipidemia and diabetes in schizophrenia: data from the CATIE schizophrenia trial sample at baseline. Schizophr. Res. 2006, 86:15-22.
    • (2006) Schizophr. Res. , vol.86 , pp. 15-22
    • Nasrallah, H.A.1    Meyer, J.M.2    Goff, D.C.3    McEvoy, J.P.4    Davis, S.M.5    Stroup, T.S.6    Lieberman, J.A.7
  • 33
    • 18744366088 scopus 로고    scopus 로고
    • Second-generation (atypical) antipsychotics and metabolic effects: a comprehensive literature review
    • Newcomer J.W. Second-generation (atypical) antipsychotics and metabolic effects: a comprehensive literature review. CNS Drugs 2005, 19(Suppl 1):1-93.
    • (2005) CNS Drugs , vol.19 , Issue.SUPPL. 1 , pp. 1-93
    • Newcomer, J.W.1
  • 35
    • 58349114259 scopus 로고    scopus 로고
    • Atypical antipsychotic drugs and the risk of sudden cardiac death
    • Ray W.A., Chung C.P., Murray K.T., Hall K., Stein C.M. Atypical antipsychotic drugs and the risk of sudden cardiac death. N. Engl. J. Med. 2009, 360:225-235.
    • (2009) N. Engl. J. Med. , vol.360 , pp. 225-235
    • Ray, W.A.1    Chung, C.P.2    Murray, K.T.3    Hall, K.4    Stein, C.M.5
  • 36
    • 34948840329 scopus 로고    scopus 로고
    • A systematic review of mortality in schizophrenia. Is the differential mortality gap worsening over time?
    • Saha S., Chant D., McGrath J. A systematic review of mortality in schizophrenia. Is the differential mortality gap worsening over time?. Arch. Gen. Psychiatry 2007, 64:1123-1131.
    • (2007) Arch. Gen. Psychiatry , vol.64 , pp. 1123-1131
    • Saha, S.1    Chant, D.2    McGrath, J.3
  • 37
    • 9644257096 scopus 로고    scopus 로고
    • Whole blood serotonin and platelet activation in depressed post-myocardial infarction patients
    • Schins A., Hamulyak K., Scharpe S., Lousberg R., Van Melle J., Crijns H., Honig A. Whole blood serotonin and platelet activation in depressed post-myocardial infarction patients. Life Sci. 2004, 76:637-650.
    • (2004) Life Sci. , vol.76 , pp. 637-650
    • Schins, A.1    Hamulyak, K.2    Scharpe, S.3    Lousberg, R.4    Van Melle, J.5    Crijns, H.6    Honig, A.7
  • 38
    • 14644388106 scopus 로고    scopus 로고
    • Obesity and associated complications in patients with severe mental illnesses: a cross-sectional survey
    • Susce M.T., Villanueva N., Diaz F.J., de Leon J. Obesity and associated complications in patients with severe mental illnesses: a cross-sectional survey. J. Clin. Psychiatry 2005, 66:167-173.
    • (2005) J. Clin. Psychiatry , vol.66 , pp. 167-173
    • Susce, M.T.1    Villanueva, N.2    Diaz, F.J.3    de Leon, J.4
  • 40
    • 68949172254 scopus 로고    scopus 로고
    • 11-year follow-up of mortality in patients with schizophrenia: a population-based cohort study (FIN11 study)
    • Tiihonen J., Lonnqvist J., Wahlbeck K., Klaukka T., Niskanen L., Tanskanen A., Haukka J. 11-year follow-up of mortality in patients with schizophrenia: a population-based cohort study (FIN11 study). Lancet 2009, 374:620-627.
    • (2009) Lancet , vol.374 , pp. 620-627
    • Tiihonen, J.1    Lonnqvist, J.2    Wahlbeck, K.3    Klaukka, T.4    Niskanen, L.5    Tanskanen, A.6    Haukka, J.7
  • 42
    • 67649854909 scopus 로고    scopus 로고
    • Influence of antipsychotics on mortality in schizophrenia: systematic review
    • Weinmann S., Read J., Aderhold V. Influence of antipsychotics on mortality in schizophrenia: systematic review. Schizophr. Res. 2009, 113:1-11.
    • (2009) Schizophr. Res. , vol.113 , pp. 1-11
    • Weinmann, S.1    Read, J.2    Aderhold, V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.