Protective effects of sarpogrelate, a 5-HT2A antagonist, against postischemic myocardial dysfunction in guinea-pig hearts

Molecular and Cellular Biochemistry

Volumn 272, Issue 1-2, 2005, Pages 119-132

  Muto, Tatsuya ^a   Hotta, Yoshihiro ^a   Miyazeki, Kunihiro ^a   Ando, Hiroaki ^a   Ishikawa, Naohisa ^a   Hasegawa, Takaaki ^a   Sugimoto, Yumi ^b   Yamada, Jun ^b   Miki, Yasuyoshi ^c  

^a AICHI MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

^c KINKI UNIVERSITY   (Japan)

Author keywords

5 HT2A antagonist; Free radicals; Langendorff hearts; Mitochondrial KATP channel; Spectroscopy

Indexed keywords

5 HYDROXYDECANOIC ACID; CALCIUM ION; DIAZOXIDE; HYDROXYL RADICAL; NITRIC OXIDE; PHOSPHORUS; POTASSIUM CHANNEL; SARPOGRELATE; SEROTONIN; SEROTONIN 2A RECEPTOR;

ACIDIFICATION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONTROLLED STUDY; DRUG MECHANISM; ELECTRON SPIN RESONANCE; FEMALE; FLUOROMETRY; GUINEA PIG; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PERFUSION; HEART PROTECTION; IN VITRO STUDY; ISOLATED HEART; MALE; NONHUMAN; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PROTEIN FUNCTION;

ANIMALS; CALCIUM; CALCIUM SIGNALING; CARDIOTONIC AGENTS; FREE RADICAL SCAVENGERS; FREE RADICALS; FURA-2; GUINEA PIGS; MITOCHONDRIA, HEART; MYOCARDIAL CONTRACTION; MYOCARDIAL REPERFUSION; MYOCARDIAL REPERFUSION INJURY; NITRIC OXIDE; PHOSPHORUS; RECEPTOR, SEROTONIN, 5-HT2A; SEROTONIN ANTAGONISTS; SUCCINATES;

CAVIA PORCELLUS;

EID: 20944434931     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11010-005-6909-0     Document Type: Article

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