Can surgical site infections be treated by photodynamic therapy?

Photodiagnosis and Photodynamic Therapy

Volumn 7, Issue 2, 2010, Pages 134-136

  Hamblin, Michael R ^a   Dai, Tianhong ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIMETHYLMETHYLENE BLUE; METHYLENE BLUE; PHOTOFRIN; PHOTOSENSITIZING AGENT; TOLUIDINE DERIVATIVE; UNCLASSIFIED DRUG;

BINDING AFFINITY; DRUG BINDING; DRUG EFFICACY; DRUG SAFETY; HUMAN; INTERMETHOD COMPARISON; LETTER; LEUKOCYTE; METHEMOGLOBINEMIA; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; SURGICAL INFECTION; SURGICAL SITE INFECTION; TREATMENT INDICATION; PHOTOCHEMOTHERAPY; SURGICAL WOUND INFECTION;

HUMANS; PHOTOCHEMOTHERAPY; SURGICAL WOUND INFECTION;

EID: 77952656308     PISSN: 15721000     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pdpdt.2010.04.004     Document Type: Letter

References (21)

1. Moghissi K. Can surgical site infection (SSI) be treated by photodynamic therapy (PDT)?. Photodiagnosis Photodyn Ther 7 (2010) 1-2
2. Ragas X, Dai T, Tegos GP, Agut M, Nonell S, Hamblin MR. Photodynamic inactivation of Acinetobacter baumannii using phenothiazinium dyes: in vitro and in vivo studies. Laser Surg Med, in press.
3. Demidova T.N., and Hamblin M.R. Effect of cell-photosensitizer binding and cell density on microbial photoinactivation. Antimicrob Agents Chemother 49 (2005) 2329-2335
4. Gad F., Zahra T., Francis K.P., Hasan T., and Hamblin M.R. Targeted photodynamic therapy of established soft-tissue infections in mice. Photochem Photobiol Sci 3 (2004) 451-458
5. Biel MA. Photodynamic therapy utilizing a solution of photosensitizing compound and surfactant. US Patent 7229447 (2007).
6. Bugaj A., Juzeniene A., Juzenas P., Iani V., Ma L.W., and Moan J. The effect of skin permeation enhancers on the formation of porphyrins in mouse skin during topical application of the methyl ester of 5-aminolevulinic acid. J Photochem Photobiol B 83 (2006) 94-97
7. Donnelly R.F., Morrow D.I., McCarron P.A., David Woolfson A., Morrissey A., Juzenas P., et al. Microneedle arrays permit enhanced intradermal delivery of a preformed photosensitizer. Photochem Photobiol 85 (2009) 195-204
8. Taberner A.J., Ball N.B., Hogan N.C., and Hunter I.W. A portable needle-free jet injector based on a custom high power-density voice-coil actuator. Conf Proc IEEE Eng Med Biol Soc 1 (2006) 5001-5004
9. Gelfuso G.M., Figueiredo F.V., Gratieri T., and Lopez R.F. The effects of pH and ionic strength on topical delivery of a negatively charged porphyrin (TPPS4). J Pharm Sci 97 (2008) 4249-4257
10. Haedersdal M., Sakamoto F.H., Farinelli W.A., Doukas A.G., Tam J., and Anderson R.R. Fractional CO(2) laser-assisted drug delivery. Lasers Surg Med 42 (2010) 113-122
11. Tanaka M., Kinoshita M., Yoshihara Y., Shinomiya N., Seki S., Nemoto K., et al. Influence of intra-articular neutrophils on the effects of photodynamic therapy for murine MRSA arthritis. Photochem Photobiol 86 (2010) 403-409
12. Hamblin M.R., O'Donnell D.A., Murthy N., Rajagopalan K., Michaud N., Sherwood M.E., et al. Polycationic photosensitizer conjugates: effects of chain length and Gram classification on the photodynamic inactivation of bacteria. J Antimicrob Chemother 49 (2002) 941-951
13. Tegos G.P., Anbe M., Yang C., Demidova T.N., Satti M., Mroz P., et al. Protease-stable polycationic photosensitizer conjugates between polyethyleneimine and chlorin(e6) for broad-spectrum antimicrobial photoinactivation. Antimicrob Agents Chemother 50 (2006) 1402-1410
14. Demeneix B., and Behr J.P. Polyethylenimine (PEI). Adv Genet 53 (2005) 217-230
15. Vicennati P., Giuliano A., Ortaggi G., and Masotti A. Polyethylenimine in medicinal chemistry. Curr Med Chem 15 (2008) 2826-2839
16. Azarpazhooh A., Shah P.S., Tenenbaum H.C., and Goldberg M.B. The effect of photodynamic therapy for periodontitis: a systematic review and meta-analysis. J Periodontol 81 (2010) 4-14
17. Wainwright M., and Crossley K.B. Methylene Blue-a therapeutic dye for all seasons?. J Chemother 14 (2002) 431-443
18. Wainwright M., Phoenix D.A., Rice L., Burrow S.M., and Waring J. Increased cytotoxicity and phototoxicity in the methylene blue series via chromophore methylation. J Photochem Photobiol B 40 (1997) 233-239
19. Tegos G.P., Masago K., Aziz F., Higginbotham A., Stermitz F.R., and Hamblin M.R. Inhibitors of bacterial multidrug efflux pumps potentiate antimicrobial photoinactivation. Antimicrob Agents Chemother 52 (2008) 3202-3209
20. Tegos G.P., and Hamblin M.R. Phenothiazinium antimicrobial photosensitizers are substrates of bacterial multidrug resistance pumps. Antimicrob Agents Chemother 50 (2006) 196-203
21. Brown SB. Clinical developments in antimicrobial PDT. In: 12th international photodynamic association world congress, Seattle, 2009.