Construction of an expression system for human α1-acid glycoprotein in E. coli: The roles of oligosaccharide moieties in structural and functional properties

Drug Metabolism and Pharmacokinetics

Volumn 25, Issue 2, 2010, Pages 200-207

  Nishi, Koji ^a,b   Fukunaga, Naoko ^a   Ono, Tomomi ^a   Akuta, Teruo ^c   Yumita, Nagahiko ^b   Watanabe, Hiroshi ^a   Kadowaki, Daisuke ^a   Suenaga, Ayaka ^a   Maruyama, Toru ^a   Otagiri, Masaki ^a,d  

^a KUMAMOTO UNIVERSITY   (Japan)

^b YOKOHAMA COLLEGE OF PHARMACY   (Japan)

^c KUMAMOTO UNIVERSITY   (Japan)

^d SOJO UNIVERSITY   (Japan)

Author keywords

E. coli; Expression system; Ligand binding; Oligosaccharide moieties; 1 acid glycoprotein

Indexed keywords

CARBOHYDRATE DERIVATIVE; CYSTEINE; DISOPYRAMIDE; LIGAND; MUTANT PROTEIN; OLIGOSACCHARIDE; OROSOMUCOID; PROPRANOLOL; RECOMBINANT PROTEIN; TRYPTOPHAN;

ARTICLE; CIRCULAR DICHROISM; CONTROLLED STUDY; DRUG BINDING SITE; DRUG RESEARCH; ESCHERICHIA COLI; GENE EXPRESSION SYSTEM; LIGAND BINDING; NONHUMAN; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; PROTEIN VARIANT;

EID: 77952593968     PISSN: 13474367     EISSN: 18800920     Source Type: Journal    
DOI: 10.2133/dmpk.25.200     Document Type: Article

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