Oxidative stress-induced antioxidant enzyme expression is an early phenomenon in ovarian carcinogenesis

European Journal of Cancer

Volumn 46, Issue 9, 2010, Pages 1661-1667

  Pylväs, Marjo ^a   Puistola, Ulla ^a   Kauppila, Saila ^a   Soini, Ylermi ^a,b   Karihtala, Peeter ^a  

^a UNIVERSITY OF OULU   (Finland)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

8 OHdG; Antioxidant enzyme; Ovarian cancer; Peroxiredoxin; Reactive oxygen species; Thioredoxin

Indexed keywords

3 NITROTYROSINE; 8 HYDROXYDEOXYGUANOSINE; CYTOTOXIC AGENT; PEROXIREDOXIN 1; PEROXIREDOXIN 2; PEROXIREDOXIN 3; PEROXIREDOXIN 4; PEROXIREDOXIN 5; PEROXIREDOXIN 6; THIOREDOXIN; 3-NITROTYROSINE; 8-OXO-7-HYDRODEOXYGUANOSINE; ANTIOXIDANT; DEOXYGUANOSINE; PEROXIREDOXIN; REACTIVE OXYGEN METABOLITE; TUMOR MARKER; TUMOR PROTEIN; TYROSINE;

ARTICLE; CARCINOGENESIS; CELL NUCLEUS; CONTROLLED STUDY; CYTOPLASM; DIAGNOSTIC VALUE; DIFFERENTIAL DIAGNOSIS; FEMALE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; OVARIECTOMY; OVARY CANCER; OVARY CARCINOMA; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR CLASSIFICATION; ANALOGS AND DERIVATIVES; COLLOID CARCINOMA; ENZYMOLOGY; IMMUNOHISTOCHEMISTRY; METABOLISM; OVARY TUMOR; PHYSIOLOGY;

ADENOCARCINOMA, MUCINOUS; ANTIOXIDANTS; DEOXYGUANOSINE; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; NEOPLASM PROTEINS; OVARIAN NEOPLASMS; OXIDATIVE STRESS; PEROXIREDOXINS; REACTIVE OXYGEN SPECIES; THIOREDOXINS; TUMOR MARKERS, BIOLOGICAL; TYROSINE;

EID: 77952585584     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejca.2010.02.006     Document Type: Article

References (17)

1. Valko M., Izakovic M., Mazur M., Rhodes C.J., and Telser J. Role of oxygen radicals in DNA damage and cancer incidence. Mol. Cell Biochem. 266 (2004) 37-56
2. Karihtala P., and Soini Y. Reactive oxygen species and antioxidant mechanisms in human tissues and their relation to malignancies. APMIS 115 (2007) 81-103
3. Rabilloud T., Heller M., Gasnier F., et al. Response to oxidative stress. Evidence for in vivo overoxidation of peroxiredoxins at their active site. J. Biol. Chem. 277 (2002) 19396-19401
4. Arnér E.S.J., and Holmgren A. The thioredoxin system in cancer. Semin. Cancer Biol. 16 (2006) 420-426
5. Karihtala P., Soini Y., Vaskivuo L., Bloigu R., and Puistola U. DNA adduct 8-hydroxydeoxiguanosine, a novel putative marker of prognostic significance in ovarian carcinoma. Int. J. Gynecol. Cancer 19 (2009) 1047-1051
6. Tavassoéli F.A., and Devilee P. Tumours of the breast and female genital organs (2003), IARC Press, WHO, Lyon
7. Halliwell B. Biochemistry of oxidative stress. Biochem. Soc. Trans. 35 (2007) 1147-1150
8. Evans M.D., Dizdaroglu M., and Cooke M.S. Oxidative DNA damage and disease: induction, repair and significance. Mutat. Res. 567 (2004) 1-61
9. Shen J., Deininger P., Hunt J.D., and Zhao H. 8-Hydroxy-2′-deoxyguanosine (8-OH-dG) as a potential survival biomarker in patients with nonsmall-cell lung cancer. Cancer 109 (2007) 574-580
10. Murawaki Y., Tsuchiya H., Kanbe T., et al. Aberrant expression of selenoproteins in the progression of colorectal cancer. Cancer Lett. 259 (2008) 218-230
11. Kondo S., Toyokuni S., Iwasa Y., et al. Persistent oxidative stress in human colorectal carcinoma, but not in adenoma. Free Radic. Biol. Med. 27 (1999) 401-410
12. Karihtala P., Winqvist R., Syväoja J.E., Kinnula V.L., and Soini Y. Increasing oxidative damage and loss of mismatch repair enzymes during breast carcinogenesis. Eur. J. Cancer 42 (2006) 2653-2659
13. Anttila M.A., Voutilainen K., Merivalo S., et al. Prognostic significance of iNOS in epithelial ovarian cancer. Gynecol. Oncol. 105 (2007) 97-103
14. Raspollini M.R., Amunni G., Villanucci A., et al. Expression of inducible nitric oxide synthase and cyclooxygenase-2 in ovarian cancer: correlation with clinical outcome. Gynecol. Oncol. 92 (2004) 806-812
15. Ishii T., and Yanagawa T. Stress-induced peroxiredoxins. Subcell. Biochem. 44 (2007) 375-384
16. Neumann C.A., Krause D.S., Carman C.V., et al. Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defense and tumor suppression. Nature 424 (2003) 561-565
17. Turunen N., Karihtala P., Mäntyniemi A., et al. Thioredoxin is associated with proliferation, p53 expression and negative estrogen and progesterone receptor status in breast carcinoma. APMIS 112 (2004) 123-132