OprF/I-vaccinated sera inhibit binding of human interferon-gamma to Pseudomonas aeruginosa

Vaccine

Volumn 28, Issue 25, 2010, Pages 4119-4122

  Ding, Bin ^a   von Specht, Bernd Ulrich ^a   Li, Yuanyi ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

IFN binding; OprF I vaccine; P. aeruginosa

Indexed keywords

BACTERIAL PROTEIN; GAMMA INTERFERON; OUTER MEMBRANE PROTEIN F; OUTER MEMBRANE PROTEIN I; PSEUDOMONAS VACCINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ANTIBODY SPECIFICITY; ARTICLE; BACTERIAL IMMUNITY; CASE REPORT; CONTROLLED STUDY; HUMAN; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTECTION; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTION; VACCINATION;

ANIMALS; ANTIBODIES, BACTERIAL; BACTERIAL PROTEINS; BACTERIAL VACCINES; HUMANS; IMMUNE SERA; INTERFERON-GAMMA; PROTEIN BINDING; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; RABBITS; RECOMBINANT PROTEINS;

EID: 77952584259     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2010.04.028     Document Type: Article

References (18)

1. Driscoll J.A., Brody S.L., and Kollef M.H. The epidemiology, pathogenesis and treatment of Pseudomonas aeruginosa infections. Drugs 67 3 (2007) 351-368
2. Doring G., and Pier G.B. Vaccines and immunotherapy against Pseudomonas aeruginosa. Vaccine 26 February (8) (2008) 1011-1024
3. Saha S., Takeshita F., Sasaki S., Matsuda T., Tanaka T., Tozuka M., et al. Multivalent DNA vaccine protects mice against pulmonary infection caused by Pseudomonas aeruginosa. Vaccine 24 September (37-39) (2006) 6240-6249
4. von Specht B.U., Knapp B., Muth G., Broker M., Hungerer K.D., Diehl K.D., et al. Protection of immunocompromised mice against lethal infection with Pseudomonas aeruginosa by active or passive immunization with recombinant P. aeruginosa outer membrane protein F and outer membrane protein I fusion proteins. Infect Immun 63 May (5) (1995) 1855-1862
5. Mansouri E., Gabelsberger J., Knapp B., Hundt E., Lenz U., Hungerer K.D., et al. Safety and immunogenicity of a Pseudomonas aeruginosa hybrid outer membrane protein F-I vaccine in human volunteers. Infect Immun 67 March (3) (1999) 1461-1470
6. Gocke K., Baumann U., Hagemann H., Gabelsberger J., Hahn H., Freihorst J., et al. Mucosal vaccination with a recombinant OprF-I vaccine of Pseudomonas aeruginosa in healthy volunteers: comparison of a systemic vs. a mucosal booster schedule. FEMS Immunol Med Microbiol 37 July (2-3) (2003) 167-171
7. Baumann U., Mansouri E., and von Specht B.U. Recombinant OprF-OprI as a vaccine against Pseudomonas aeruginosa infections. Vaccine 22 February (7) (2004) 840-847
8. Larbig M., Mansouri E., Freihorst J., Tummler B., Kohler G., Domdey H., et al. Safety and immunogenicity of an intranasal Pseudomonas aeruginosa hybrid outer membrane protein F-I vaccine in human volunteers. Vaccine 19 March (17-19) (2001) 2291-2297
9. Mansouri E., Blome-Eberwein S., Gabelsberger J., Germann G., and von Specht B.U. Clinical study to assess the immunogenicity and safety of a recombinant Pseudomonas aeruginosa OprF-OprI vaccine in burn patients. FEMS Immunol Med Microbiol 37 July (2-3) (2003) 161-166
10. Sorichter S., Baumann U., Baumgart A., Walterspacher S., and von Specht B.U. Immune responses in the airways by nasal vaccination with systemic boosting against Pseudomonas aeruginosa in chronic lung disease. Vaccine 27 May (21) (2009) 2755-2759
11. Schroder K., Hertzog P.J., Ravasi T., and Hume D.A. Interferon-gamma: an overview of signals, mechanisms and functions. J Leukoc Biol 75 February (2) (2004) 163-189
12. Boehm U., Klamp T., Groot M., and Howard J.C. Cellular responses to interferon-gamma. Annu Rev Immunol 15 (1997) 749-795
13. Murphey E.D., Herndon D.N., and Sherwood E.R. Gamma interferon does not enhance clearance of Pseudomonas aeruginosa but does amplify a proinflammatory response in a murine model of postseptic immunosuppression. Infect Immun 72 December (12) (2004) 6892-6901
14. Wu L., Estrada O., Zaborina O., Bains M., Shen L., Kohler J.E., et al. Recognition of host immune activation by Pseudomonas aeruginosa. Science 309 July (5735) (2005) 774-777
15. Baumann U., Gocke K., Gewecke B., Freihorst J., and von Specht B.U. Assessment of pulmonary antibodies with induced sputum and bronchoalveolar lavage induced by nasal vaccination against Pseudomonas aeruginosa: a clinical phase I/II study. Respir Res 8 (2007) 57
16. Jang I.J., Kim I.S., Park W.J., Yoo K.S., Yim D.S., Kim H.K., et al. Human immune response to a Pseudomonas aeruginosa outer membrane protein vaccine. Vaccine 17 January (2) (1999) 158-168
17. Rawling E.G., Martin N.L., and Hancock R.E. Epitope mapping of the Pseudomonas aeruginosa major outer membrane porin protein OprF. Infect Immun 63 January (1) (1995) 38-42
18. Farrar M.A., and Schreiber R.D. The molecular cell biology of interferon-gamma and its receptor. Annu Rev Immunol 11 (1993) 571-611