-
1
-
-
33747276441
-
Pharmacology of the human CGRP1 receptor in Cos 7 cells
-
Bailey R.J., and Hay D.L. Pharmacology of the human CGRP1 receptor in Cos 7 cells. Peptides 27 (2006) 1367-1375
-
(2006)
Peptides
, vol.27
, pp. 1367-1375
-
-
Bailey, R.J.1
Hay, D.L.2
-
2
-
-
34347349008
-
Agonist-dependent consequences of proline to alanine substitution in the transmembrane helices of the calcitonin receptor
-
Bailey R.J., and Hay D.L. Agonist-dependent consequences of proline to alanine substitution in the transmembrane helices of the calcitonin receptor. Br J Pharmacol 151 (2007) 678-687
-
(2007)
Br J Pharmacol
, vol.151
, pp. 678-687
-
-
Bailey, R.J.1
Hay, D.L.2
-
3
-
-
69249087312
-
Juxtamembranous region of the amino terminus of the family B G protein-coupled calcitonin receptor plays a critical role in small-molecule agonist action
-
Dong M., Cox R.F., and Miller L.J. Juxtamembranous region of the amino terminus of the family B G protein-coupled calcitonin receptor plays a critical role in small-molecule agonist action. J Biol Chem 284 (2009) 21839-21847
-
(2009)
J Biol Chem
, vol.284
, pp. 21839-21847
-
-
Dong, M.1
Cox, R.F.2
Miller, L.J.3
-
4
-
-
17844365264
-
Pharmacological discrimination of calcitonin receptor: receptor activity-modifying protein complexes
-
Hay D.L., Christopoulos G., Christopoulos A., Poyner D.R., and Sexton P.M. Pharmacological discrimination of calcitonin receptor: receptor activity-modifying protein complexes. Mol Pharmacol 67 (2005) 1655-1665
-
(2005)
Mol Pharmacol
, vol.67
, pp. 1655-1665
-
-
Hay, D.L.1
Christopoulos, G.2
Christopoulos, A.3
Poyner, D.R.4
Sexton, P.M.5
-
5
-
-
33751073196
-
Determinants of 1-piperidinecarboxamide, N-[2-[[5-amino-l-[[4-(4-pyridinyl)-l-piperazinyl]carbonyl]pentyl]amino]- 1-[(3,5-dibromo-4-hydroxyphenyl)methyl]-2-oxoethyl]-4-(1,4-dihydro-2-oxo -3(2H)-quinazolinyl) (BIBN4096BS) affinity for calcitonin gene-related peptide and amylin receptors - the role of receptor activity modifying protein 1
-
Hay D.L., Christopoulos G., Christopoulos A., and Sexton P.M. Determinants of 1-piperidinecarboxamide, N-[2-[[5-amino-l-[[4-(4-pyridinyl)-l-piperazinyl]carbonyl]pentyl]amino]- 1-[(3,5-dibromo-4-hydroxyphenyl)methyl]-2-oxoethyl]-4-(1,4-dihydro-2-oxo -3(2H)-quinazolinyl) (BIBN4096BS) affinity for calcitonin gene-related peptide and amylin receptors - the role of receptor activity modifying protein 1. Mol Pharmacol 70 (2006) 1984-1991
-
(2006)
Mol Pharmacol
, vol.70
, pp. 1984-1991
-
-
Hay, D.L.1
Christopoulos, G.2
Christopoulos, A.3
Sexton, P.M.4
-
6
-
-
16244383540
-
Mechanisms of peptide and nonpeptide ligand binding to Class B G-protein-coupled receptors
-
Hoare S.R. Mechanisms of peptide and nonpeptide ligand binding to Class B G-protein-coupled receptors. Drug Discov Today 10 (2005) 417-427
-
(2005)
Drug Discov Today
, vol.10
, pp. 417-427
-
-
Hoare, S.R.1
-
7
-
-
77749255462
-
Refolding and characterization of a soluble ectodomain complex of the calcitonin gene-related peptide receptor
-
Koth C.M., Abdul-Manan N., Lepre C.A., Connolly P.J., Yoo S., Mohanty A.K., et al. Refolding and characterization of a soluble ectodomain complex of the calcitonin gene-related peptide receptor. Biochemistry 49 (2010) 1862-1872
-
(2010)
Biochemistry
, vol.49
, pp. 1862-1872
-
-
Koth, C.M.1
Abdul-Manan, N.2
Lepre, C.A.3
Connolly, P.J.4
Yoo, S.5
Mohanty, A.K.6
-
8
-
-
55549092099
-
Crystal structure of the human receptor activity-modifying protein 1 extracellular domain
-
Kusano S., Kukimoto-Niino M., Akasaka R., Toyama M., Terada T., Shirouzu M., et al. Crystal structure of the human receptor activity-modifying protein 1 extracellular domain. Protein Sci 17 (2008) 1907-1914
-
(2008)
Protein Sci
, vol.17
, pp. 1907-1914
-
-
Kusano, S.1
Kukimoto-Niino, M.2
Akasaka, R.3
Toyama, M.4
Terada, T.5
Shirouzu, M.6
-
9
-
-
1642576970
-
Characterization of the human calcitonin gene-related peptide receptor subtypes associated with receptor activity-modifying proteins
-
Kuwasako K., Cao Y.N., Nagoshi Y., Tsuruda T., Kitamura K., and Eto T. Characterization of the human calcitonin gene-related peptide receptor subtypes associated with receptor activity-modifying proteins. Mol Pharmacol 65 (2004) 207-213
-
(2004)
Mol Pharmacol
, vol.65
, pp. 207-213
-
-
Kuwasako, K.1
Cao, Y.N.2
Nagoshi, Y.3
Tsuruda, T.4
Kitamura, K.5
Eto, T.6
-
10
-
-
33750355471
-
Amylinergic control of food intake
-
Lutz T.A. Amylinergic control of food intake. Physiol Behav 89 (2006) 465-471
-
(2006)
Physiol Behav
, vol.89
, pp. 465-471
-
-
Lutz, T.A.1
-
11
-
-
0037134498
-
Receptor activity-modifying protein 1 determines the species selectivity of non-peptide CGRP receptor antagonists
-
Mallee J.J., Salvatore C.A., LeBourdelles B., Oliver K.R., Longmore J., Koblan K.S., et al. Receptor activity-modifying protein 1 determines the species selectivity of non-peptide CGRP receptor antagonists. J Biol Chem 277 (2002) 14294-14298
-
(2002)
J Biol Chem
, vol.277
, pp. 14294-14298
-
-
Mallee, J.J.1
Salvatore, C.A.2
LeBourdelles, B.3
Oliver, K.R.4
Longmore, J.5
Koblan, K.S.6
-
12
-
-
0032574982
-
RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor
-
McLatchie L.M., Fraser N.J., Main M.J., Wise A., Brown J., Thompson N., et al. RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor. Nature 393 (1998) 333-339
-
(1998)
Nature
, vol.393
, pp. 333-339
-
-
McLatchie, L.M.1
Fraser, N.J.2
Main, M.J.3
Wise, A.4
Brown, J.5
Thompson, N.6
-
13
-
-
77949873859
-
Mapping the CGRP receptor ligand binding domain: tryptophan-84 of RAMP1 is critical for agonist and antagonist binding
-
Moore E.L., Gingell J.J., Kane S.A., Hay D.L., and Salvatore C.A. Mapping the CGRP receptor ligand binding domain: tryptophan-84 of RAMP1 is critical for agonist and antagonist binding. Biochem Biophys Res Commun 394 (2010) 141-145
-
(2010)
Biochem Biophys Res Commun
, vol.394
, pp. 141-145
-
-
Moore, E.L.1
Gingell, J.J.2
Kane, S.A.3
Hay, D.L.4
Salvatore, C.A.5
-
14
-
-
1342282976
-
Spatial proximity between a photolabile residue in position 19 of salmon calcitonin and the amino terminus of the human calcitonin receptor
-
Pham V., Wade J.D., Purdue B.W., and Sexton P.M. Spatial proximity between a photolabile residue in position 19 of salmon calcitonin and the amino terminus of the human calcitonin receptor. J Biol Chem 279 (2004) 6720-6729
-
(2004)
J Biol Chem
, vol.279
, pp. 6720-6729
-
-
Pham, V.1
Wade, J.D.2
Purdue, B.W.3
Sexton, P.M.4
-
15
-
-
23344453698
-
Insights into interactions between the alpha-helical region of the salmon calcitonin antagonists and the human calcitonin receptor using photoaffinity labeling
-
Pham V., Dong M., Wade J.D., Miller L.J., Morton C.J., Ng H.L., et al. Insights into interactions between the alpha-helical region of the salmon calcitonin antagonists and the human calcitonin receptor using photoaffinity labeling. J Biol Chem 280 (2005) 28610-28622
-
(2005)
J Biol Chem
, vol.280
, pp. 28610-28622
-
-
Pham, V.1
Dong, M.2
Wade, J.D.3
Miller, L.J.4
Morton, C.J.5
Ng, H.L.6
-
16
-
-
0036266044
-
International Union of Pharmacology. XXXII. The mammalian calcitonin gene-related peptides, adrenomedullin, amylin, and calcitonin receptors
-
Poyner D.R., Sexton P.M., Marshall I., Smith D.M., Quirion R., Born W., et al. International Union of Pharmacology. XXXII. The mammalian calcitonin gene-related peptides, adrenomedullin, amylin, and calcitonin receptors. Pharmacol Rev 54 (2002) 233-246
-
(2002)
Pharmacol Rev
, vol.54
, pp. 233-246
-
-
Poyner, D.R.1
Sexton, P.M.2
Marshall, I.3
Smith, D.M.4
Quirion, R.5
Born, W.6
-
17
-
-
52949141814
-
Identification of N-terminal receptor activity-modifying protein residues important for calcitonin gene-related peptide, adrenomedullin, and amylin receptor function
-
Qi T., Christopoulos G., Bailey R.J., Christopoulos A., Sexton P.M., and Hay D.L. Identification of N-terminal receptor activity-modifying protein residues important for calcitonin gene-related peptide, adrenomedullin, and amylin receptor function. Mol Pharmacol 74 (2008) 1059-1071
-
(2008)
Mol Pharmacol
, vol.74
, pp. 1059-1071
-
-
Qi, T.1
Christopoulos, G.2
Bailey, R.J.3
Christopoulos, A.4
Sexton, P.M.5
Hay, D.L.6
-
18
-
-
74949097404
-
Structure-function analysis of RAMP1-RAMP3 chimeras
-
Qi T., Simms J., Bailey R.J., Wheatley M., Rathbone D.L., Hay D.L., et al. Structure-function analysis of RAMP1-RAMP3 chimeras. Biochemistry 49 (2009) 522-531
-
(2009)
Biochemistry
, vol.49
, pp. 522-531
-
-
Qi, T.1
Simms, J.2
Bailey, R.J.3
Wheatley, M.4
Rathbone, D.L.5
Hay, D.L.6
-
19
-
-
28444467706
-
Pramlintide in the treatment of type 1 and type 2 diabetes mellitus
-
Ryan G.J., Jobe L.J., and Martin R. Pramlintide in the treatment of type 1 and type 2 diabetes mellitus. Clin Ther 27 (2005) 1500-1512
-
(2005)
Clin Ther
, vol.27
, pp. 1500-1512
-
-
Ryan, G.J.1
Jobe, L.J.2
Martin, R.3
-
20
-
-
62849124664
-
-
Sexton P.M., Poyner D.R., Simms J., Christopoulos A., Hay D.L., and Modulating receptor function through RAMPs: can they represent drug targets in themselves?. Drug Discov Today 14 (2009) 413-419
-
(2009)
Drug Discov Today
, vol.14
, pp. 413-419
-
-
Sexton, P.M.1
Poyner, D.R.2
Simms, J.3
Christopoulos, A.4
Hay, D.L.5
-
21
-
-
58549084401
-
Structure-function analysis of RAMP1 by alanine mutagenesis
-
Simms J., Hay D.L., Bailey R.J., Konycheva G., Bailey G., Wheatley M., et al. Structure-function analysis of RAMP1 by alanine mutagenesis. Biochemistry 48 (2009) 198-205
-
(2009)
Biochemistry
, vol.48
, pp. 198-205
-
-
Simms, J.1
Hay, D.L.2
Bailey, R.J.3
Konycheva, G.4
Bailey, G.5
Wheatley, M.6
-
22
-
-
0025366838
-
Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation
-
Westermark P., Engstrom U., Johnson K.H., Westermark G.T., and Betsholtz C. Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation. Proc Natl Acad Sci USA 87 (1990) 5036-5040
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 5036-5040
-
-
Westermark, P.1
Engstrom, U.2
Johnson, K.H.3
Westermark, G.T.4
Betsholtz, C.5
|