Hexylether derivative of pyropheophorbide-a (HPPH) on conjugating with 3Gadolinium(III) aminobenzyldiethylenetriaminepentaacetic acid shows potential for in vivo tumor imaging (MR, Fluorescence) and photodynamic therapy

Bioconjugate Chemistry

Volumn 21, Issue 5, 2010, Pages 828-835

  Spernyak, Joseph A ^a   White, William H ^a   Ethirajan, Manivannan ^a   Patel, Nayan J ^a   Goswami, Lalit ^a   Chen, Yihui ^a   Turowski, Steven ^a   Missert, Joseph R ^a   Batt, Carrie ^a   Mazurchuk, Richard ^a   Pandey, Ravindra K ^a  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORESCENCE; GADOLINIUM COMPOUNDS; TUMORS;

ACID MOIETY; DIETHYLENETRIAMINE; IN-VIVO; MR SIGNALS; POST INJECTION; PYROPHEOPHORBIDE A; TUMOR IMAGING; TUMOR MODELS; VIVO STUDIES; WATERSOLUBLE;

PHOTODYNAMIC THERAPY;

CARBON 14; ETHER DERIVATIVE; GADOLINIUM AMINOBENZYLDIETHYLENETRIAMINEPENTAACETIC ACID 3 (1' HEXYLOXYETHYL) 3 DEVINYL PYROPHEOPHORBIDE A CONJUGATE; GADOLINIUM PENTETATE; NUCLEAR MAGNETIC RESONANCE IMAGING AGENT; UNCLASSIFIED DRUG; WATER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLORECTAL CANCER; CONJUGATION; CONTROLLED STUDY; DRUG UPTAKE; FEMALE; FLUORESCENCE IMAGING; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PH; PHOTODYNAMIC THERAPY; PHOTOTHERAPY; RAT; TUMOR MODEL;

MUS; RATTUS;

EID: 77952575061     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc9005317     Document Type: Article

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