Cumulative pregnancy probabilities among couples with subfertility: Effects of varying treatments

Fertility and Sterility

Volumn 93, Issue 7, 2010, Pages 2175-2181

  Stanford, Joseph B ^a   Mikolajczyk, Rafael T ^b,c   Lynch, Courtney D ^b,d   Simonsen, Sara E ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^c BIELEFELD UNIVERSITY   (Germany)

^d OHIO STATE UNIVERSITY   (United States)

Author keywords

Fertility; Fertility agents; In vitro fertilization; Infertility; Statistical models

Indexed keywords

ANOVULATION; ARTICLE; CONSERVATIVE TREATMENT; DIAGNOSTIC PROCEDURE; FERTILIZATION IN VITRO; GYNECOLOGIC DISEASE; PREGNANCY RATE; PRIORITY JOURNAL; SIMULATION; SUBFERTILITY; TREATMENT OUTCOME; TUBAL OBSTRUCTION; COMPUTER SIMULATION; EVALUATION; FEMALE; FERTILITY; HUMAN; INFERTILITY; INFERTILITY THERAPY; MALE; PHYSIOLOGY; PREGNANCY; PROBABILITY; SENSITIVITY AND SPECIFICITY; SEXUAL BEHAVIOR; STATISTICAL MODEL; STATISTICS; TIME; UTILIZATION REVIEW;

COMPUTER SIMULATION; FEMALE; FERTILITY; HUMANS; INFERTILITY; MALE; MODELS, STATISTICAL; PREGNANCY; PREGNANCY RATE; PROBABILITY; REPRODUCTIVE TECHNIQUES, ASSISTED; SENSITIVITY AND SPECIFICITY; SEXUAL BEHAVIOR; TIME FACTORS;

EID: 77952558864     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2009.01.080     Document Type: Article

References (64)

1. American Society for Reproductive Medicine. Definitionof "infertility". Fertil Steril 2004;82:206.
2. Oakley L, Doyle P, Maconochie N. Lifetime prevalence of infertility and infertility treatment in the UK: results from a population-based survey of reproduction. Hum Reprod 2008;23:447-50.
3. Evers JL. Female subfertility. Lancet 2002;360:151-9.
4. Guzick DS, Grefenstette I, Baffone K, Berga SL, Krasnow JS, Stovall DW, et al. Infertility evaluation in fertile women: a model for assessing the efficacy of infertility testing. Hum Reprod 1994;9:2306-10.
5. Goverde AJ, McDonnell J, Vermeiden JP, Schats R, Rutten FF, Schoemaker J. Intrauterine insemination or in-vitro fertilisation in idio-pathic subfertility and male subfertility: a randomised trial and cost-effectiveness analysis. Lancet 2000;355:13-8.
6. Guzick DS, Sullivan MW, Adamson GD, Cedars MI, Falk RJ, Peterson EP, et al. Efficacy of treatment for unexplained infertility. Fertil Steril 1998;70:207-13.
7. Guzick DS, Overstreet JW, Factor-Litvak P, Brazil CK, Nakajima ST, Coutifaris C, et al. Sperm morphology, motility, and concentration in fertile and infertile men. N Engl J Med 2001;345:1388-93.
8. Hunault CC, Habbema JD, Eijkemans MJ, Collins JL, Evers JL. Two new prediction rules for spontaneous pregnancy leading to live births among subfertile couples, based on the synthesis of three previous models. Hum Reprod 2004;19:2019-26.
9. Crosignani PG, Rubin BL, ESHRE Capri Workshop Group. Optimal useof infertility diagnostic tests and treatments. Hum Reprod 2000;15:723-32.
10. Adamson GD, Baker VL. Subfertility: causes, treatment and outcome. Best Pract Res Clin Obstet Gynaecol 2003;17:169-85.
11. Guzick DS, Carson SA, Coutifaris C, Overstreet JW, Factor-Litvak P, Steinkampf MP, et al. Efficacy of superovulation and intrauterine insemination in the treatment of infertility. N Engl J Med 1999;340:177-83.
12. Peterson CM, Hatasaka HH, Jones KP, Poulson AM Jr, Carrell DT, Urry RL. Ovulation induction with gonadotropins and intrauterine insemination compared with invitro fertilization and notherapy:a prospective, nonrandomized, cohort study and meta-analysis. Fertil Steril 1994;62:535-44.
13. Crosignani PG, Walters DE, Soliani A, European Society of Human Reproduction and Embryology. The ESHRE multicentre trial on the treatment of unexplained infertility: a preliminary report. Hum Reprod 1991;6:953-8.
14. Athaullah N, Proctor M, Johnson NP. Oral versus injectable ovulation induction agents for unexplained subfertility. Cochrane Database Syst Rev 2002:CD003052.
15. Verhulst SM, Cohlen BJ, Hughes E, Heineman MJ, Te Velde E. Intra-uterine insemination for unexplained subfertility (protocol). Cochrane Database Syst Rev 2005;4.
16. Pandian Z, Bhattacharya S, Vale L, Templeton A. Invitro fertilisation for unexplained subfertility. Cochrane Database Syst Rev 2005:CD003357.
17. Hughes E, Collins J, Vandekerckhove P. Clomiphene citrate for unexplained subfertility in women. Cochrane Database Syst Rev 2000: CD000057.
18. American Society for Reproductive Medicine. Effectiveness and treatment for unexplained infertility. Fertil Steril 2006;86:S111-4.
19. Barlow DH. The design, publication and interpretation of research in subfertility medicine: uncomfortable issues and challenges to be faced. Hum Reprod 2003;18:899-901.
20. Daya S. Pitfalls in the design and analysis of efficacy trials in subfertility. Hum Reprod 2003;18:1005-9.
21. te Velde ER, Eijkemans R, Habbema HD. Variation in couple fecundity and time to pregnancy, an essential concept in human reproduction. Lancet 2000;355:1928-9.
22. Gleicher N, Weghofer A, Barad D. A formal comparison of the practice of assisted reproductive technologies between Europe and the USA. Hum Reprod 2006;21:1945-50.
23. American Society for Reproductive Medicine. Assisted reproductive technology in the United States: 2001 results generated from the American Society for Reproductive Medicine/Society for Assisted Reproductive Technology registry. Fertil Steril 2007;87:1253-66.
24. Aboulghar MA, Mansour RT, Serour GI, Al-Inany HG. Diagnosis and management of unexplained infertility: an update. Arch Gynecol Obstet 2003;267:177-88.
25. Pashayan N, Lyratzopoulos G, Mathur R. Cost-effectiveness of primary offer of IVF vs. primary offer of IUI followed by IVF (for IUI failures) in couples with unexplained or mild male factor subfertility. BMC Health Serv Res 2006;6:80.
26. Ecochard R. Heterogeneity in fecundability studies: issues and modelling. Stat Methods Med Res 2006;15:141-60.
27. Weinberg CR, Gladen BC. The beta-geometric distribution applied to comparative fecundability studies. Biometrics 1986;42:547-60.
28. Ellish NJ, Saboda K, O'Connor J, Nasca PC, Stanek EJ, Boyle C. A prospective study of early pregnancy loss. Hum Reprod 1996;11:406-12.
29. Bonde JP, Hjollund NH, Jensen TK, Ernst E, Kolstad H, Henriksen TB, et al. A follow-up study of environmental and biologic determinants of fertility among 430 Danish first-pregnancy planners: design and methods. Reprod Toxicol 1998;12:19-27.
30. Buck GM, Lynch CD, Stanford JB, Sweeney AM, Schieve LA, Rockett JC, et al. Prospective pregnancy study designs for assessing reproductive and developmental toxicants. Environ Health Perspect 2004;112:79-86.
31. Gnoth C, Godehardt D, Godehardt E, Frank-Herrmann P, Freundl G. Time to pregnancy: results of the German prospective study and impact on the management of infertility. Hum Reprod 2003;18:1959-66.
32. Zinaman MJ, Clegg ED, Brown CC, O'Connor J, Selevan SG. Estimates of human fertility and pregnancy loss. Fertil Steril 1996;65:503-9.
33. Dunson DB, Baird DD, Colombo B. Increased infertility with age in men and women. Obstet Gynecol 2004;103:51-6.
34. Larsen U. Research on infertility: which definition should we use? Fertil Steril 2005;83:846-52.
35. Rowe PJ, World Health Organization. WHO manual for the standardized investigation and diagnosis of the infertile couple. Cambridge and New York: Cambridge University Press, 1993.
36. Silverberg K, Daya S, Auray JP, Duru G, Ledger W, Wikland M, et al. Analysis of the cost effectiveness of recombinant versus urinary follicle-stimulating hormone in in vitro fertilization/intracytoplasmic sperm injection programs in the United States. Fertil Steril 2002;77:107-13.
37. Gnoth C, Frank-Herrmann P, Freundl G. Opinion: natural family planning and the management of infertility. Arch Gynecol Obstet 2002;267:67-71.
38. Stanford JB, Dunson DB. Effects of sexual intercourse patterns in time to pregnancy studies. Am J Epidemiol 2007;165:1688-95.
39. National Collaborating Centre for Women's and Children's Health (United Kingdom). Fertility assessment and treatment for people with fertility problems. In: National Institute for Clinical Excellence. Royal College of Obstetricians and Gynaecologists Press, London 2004.
40. Lintsen AM, Eijkemans MJ, Hunault CC, Bouwmans CA, Hakkaart L, Habbema JD, et al. Predicting ongoing pregnancy chances after IVF and ICSI: a national prospective study. Hum Reprod 2007;22:2455-62.
41. Snick HK, Snick TS, Evers JL, Collins JA. The spontaneous pregnancy prognosis in untreated subfertile couples: the Walcheren primary care study. Hum Reprod 1997;12:1582-8.
42. van der Steeg JW, Steures P, Eijkemans MJ, Habbema JD, Hompes PG, Broekmans FJ, et al. Pregnancy is predictable: a large-scale prospective external validation of the prediction of spontaneous pregnancy in subfer-tile couples. Hum Reprod 2007;22:536-42.
43. Collins JA, Burrows EA, Wilan AR. The prognosis for live birth among untreated infertile couples. Fertil Steril 1995;64:22-8.
44. Eijkemans MJC, Lintsen AME, Hunault CC, Bouwmans CAM, Hakkaart L, Braat DDM, et al. Pregnancy chances on an IVF/ICSI waiting list: a national prospective cohort study. Hum Reprod 2008;23:1627-32.
45. Tan SL, Royston P, Campbell S, Jacobs HS, Betts J, Mason B, et al. Cumulative conception and livebirth rates after in-vitro fertilisation. Lancet 1992;339:1390-4.
46. Stolwijk AM, Hamilton CJ, Hollanders JM, Bastiaans LA, Zielhuis GA. A more realistic approach to the cumulative pregnancy rate after in-vitro fertilization. Hum Reprod 1996;11:660-3.
47. Stolwijk AM, Wetzels AM, Braat DD. Cumulative probability of achieving an ongoing pregnancy after in-vitro fertilization and intracytoplasmic sperm injection according to a woman's age, subfertility diagnosis and primary or secondary subfertility. Hum Reprod 2000;15:203-9.
48. Cohlen BJ, Vandekerckhove P, te Velde ER, Habbema JD. Timed intercourse versus intra-uterine insemination with or without ovarian hyper-stimulation for subfertility in men. Cochrane Database Syst Rev 2000: CD000360.
49. Bhattacharya S, Harrild K, Mollison J, Wordsworth S, Tay C, Harrold A, et al. Clomifene citrate or unstimulated intrauterine insemination compared with expectant management for unexplained infertility: pragmatic randomised controlled trial. BMJ 2008;337:a716.
50. Stanford JB, Parnell TA, Boyle PC. Outcomes from treatment of infertility with natural procreative technology in an Irish general practice. J Am Board Fam Med 2008;21:375-84.
51. Jacobson TZ, Barlow DH, Koninckx PR, Olive D, Farquhar C. Laparo-scopic surgery for subfertility associated with endometriosis. Cochrane Database Syst Rev 2002.
52. Farquhar CM. The role of ovarian surgery in polycystic ovary syndrome. Best Pract Res Clin Obstet Gynaecol 2004;18:789-802.
53. Wilcox AJ, Dunson D, Baird DD. The timing of the "fertile window" in the menstrual cycle: day specific estimates from a prospective study. Br Med J 2000;321:1259-62.
54. Stanford JB, White GL, Hatasaka H. Timing intercourse to achieve pregnancy: current evidence. Obstet Gynecol 2002;100:1333-41.
55. Keulers MJ, Hamilton CJCM, Franx A, Evers JLH, Bots RSGM. The length of the fertile window is associated with the chance of spontaneously conceiving an ongoing pregnancy in subfertile couples. Hum Reprod 2007;22:1652-6.
56. Stanford JB, Smith KR, Dunson DB. Vulvar mucus observations and the probability of pregnancy. Obstet Gynecol 2003;101:1285-93.
57. Robinson JE, Wakelin M, Ellis JE. Increased pregnancy rate with use of the Clearblue Easy Fertility Monitor. Fertil Steril 2007;87:329-34.
58. Bigelow JL, Dunson DB, Stanford JB, Ecochard R, Gnoth C, Colombo B. Mucus observations in the fertile window: a better predictor of conception than timing of intercourse. Hum Reprod 2004;19:889-92.
59. Leridon H. A new estimate of permanent sterility by age: sterility defined as the inability to conceive. Popul Stud (Camb) 2008;62:15-24.
60. Leridon H. Can assisted reproduction technology compensate for the natural decline in fertility with age? A model assessment. Hum Reprod 2004;19:1548-53.
61. American Society for Reproductive Medicine. Optimal evaluation of the infertile female. Fertil Steril 2004;82:169-72.
62. American Society for Reproductive Medicine. Report on optimal evaluation of the infertile male. Fertil Steril 2004;82:123-30.
63. American Society for Reproductive Medicine. Aging and infertility in women. Fertil Steril 2004;82:102-6.
64. Van Voorhis BJ. Outcomes from assisted reproductive technology. Obstet Gynecol 2006;107:183-200.