Frontal hypoperfusion in depressed patients with dementia of Alzheimer type demonstrated on 3DSRT

Psychiatry and Clinical Neurosciences

Volumn 64, Issue 3, 2010, Pages 293-298

  Kataoka, Kouhei ^a   Hashimoto, Hiroshi ^a   Kawabe, Joji ^a   Higashiyama, Shigeaki ^a   Akiyama, Hisanori ^a   Shimada, Aiko ^a   Kai, Toshihiro ^b   Inoue, Koki ^a   Shiomi, Susumu ^a   Kiriike, Nobuo ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OSAKA CITY GENERAL HOSPITAL   (Japan)

Author keywords

3 D stereotactic region of interest template; Dementia; Dementia of Alzheimer type; Depression; Single photon emission computed tomography

Indexed keywords

CYSTEINE ETHYL ESTER TC 99M;

AGED; ALZHEIMER DISEASE; ARTICLE; BRAIN BLOOD FLOW; CLINICAL ARTICLE; COMPUTER PROGRAM; CONTROLLED STUDY; DEMENTIA; DEPRESSION; FEMALE; FRONTAL CORTEX; HUMAN; IMAGE ANALYSIS; IMAGE DISPLAY; MALE; NEUROIMAGING; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; THREE DIMENSIONAL STEREOTACTIC REGION OF INTEREST TEMPLATE; BLOOD FLOW; BRAIN; COMPLICATION; FRONTAL LOBE; PATHOPHYSIOLOGY; PHYSIOLOGY; PROCEDURES; SCINTISCANNING; THREE DIMENSIONAL IMAGING; VASCULARIZATION;

AGED; ALZHEIMER DISEASE; BRAIN; DEPRESSION; FEMALE; FRONTAL LOBE; HUMANS; IMAGING, THREE-DIMENSIONAL; MALE; REGIONAL BLOOD FLOW; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 77952557949     PISSN: 13231316     EISSN: 14401819     Source Type: Journal    
DOI: 10.1111/j.1440-1819.2010.02083.x     Document Type: Article

References (19)

1. Vilalta-Franch J, Garre-Olmo J, Lopez-Pousa S et al. Comparison of different clinical diagnostic criteria for depression in Alzheimer disease. Am. J. Geriatr. Psychiatry 2006 14 : 589 597.
2. Mizumura S, Kumita S. Stereotactic statistical imaging analysis of the brain using the easy Z-score imaging system for sharing a normal database. Radiat. Med. 2006 24 : 545 552.
3. Akiyama H, Hashimoto H, Kawabe J et al. The relationship between depressive symptoms and prefrontal hypoperfusion demonstrated by eZIS in patients with DAT. Neurosci. Lett. 2008 441 : 328 331.
4. Cummings JL, Mega M, Gray K, Rosenberg-Thompson S, Carusi DA, Gornbein J. The Neuropsychiatric Inventory: Comprehensive assessment of psychopathology in dementia. Neurology 1994 44 : 2308 2314.
5. Hirono N, Mori E, Ikejiri Y et al. [Japanese version of the Neuropsychiatric Inventory: A scoring system for neuropsychiatric disturbances in dementia patients]. No To Shinkei 1997 49 : 266 271.
6. Takeuchi R, Sengoku T, Matsumura K. Usefulness of fully automated constant ROI analysis software for the brain: 3DSRT and FineSRT. Radiat. Med. 2006 24 : 538 544.
7. Kim KW, Lee DY, Jhoo JH et al. Diagnostic accuracy of mini-mental status examination and revised Hasegawa dementia scale for Alzheimer's disease. Dement. Geriatr. Cogn. Disord. 2005 19 : 324 330.
8. Berg L. Clinical Dementia Rating (CDR). Psychopharmacol. Bull. 1988 24 : 637 639.
9. Higashiyama S, Kawabe J, Hashimoto H et al. 3DSRT evaluation of responses of Alzheimer type dementia to donepezil hydrochloride therapy. Osaka City Med. J. 2006 52 : 55 62.
10. Pickut BA, Dierckx RA, Dobbeleir A et al. Validation of the cerebellum as a reference region for SPECT quantification in patients suffering from dementia of the Alzheimer type. Psychiatry Res. 1999 90 : 103 112.
11. Levy-Cooperman N, Burhan AM, Rafi-Tari S et al. Frontal lobe hypoperfusion and depressive symptoms in Alzheimer disease. J. Psychiatry Neurosci. 2008 33 : 218 226.
12. Ito H, Kawashima R, Awata S et al. Hypoperfusion in the limbic system and prefrontal cortex in depression: SPECT with anatomic standardization technique. J. Nucl. Med. 1996 37 : 410 414.
13. Liao YC, Liu RS, Lee YC et al. Selective hypoperfusion of anterior cingulate gyrus in depressed AD patients: A brain SPECT finding by statistical parametric mapping. Dement. Geriatr. Cogn. Disord. 2003 16 : 238 244.
14. Lee DY, Choo IH, Jhoo JH et al. Frontal dysfunction underlies depressive syndrome in Alzheimer disease: A FDG-PET study. Am. J. Geriatr. Psychiatry 2006 14 : 625 628.
15. Holthoff VA, Beuthien-Baumann B, Kalbe E et al. Regional cerebral metabolism in early Alzheimer's disease with clinically significant apathy or depression. Biol. Psychiatry 2005 57 : 412 421.
16. Mayberg HS, Starkstein SE, Sadzot B et al. Selective hypometabolism in the inferior frontal lobe in depressed patients with Parkinson's disease. Ann. Neurol. 1990 28 : 57 64.
17. Mayberg HS, Starkstein SE, Peyser CE, Brandt J, Dannals RF, Folstein SE. Paralimbic frontal lobe hypometabolism in depression associated with Huntington's disease. Neurology 1992 42 : 1791 1797.
18. Kobayashi S, Tateno M, Utsumi K et al. Quantitative analysis of brain perfusion SPECT in Alzheimer's disease using a fully automated regional cerebral blood flow quantification software, 3DSRT. J. Neurol. Sci. 2008 264 : 27 33.
19. Ishii K, Sasaki M, Kitagaki H et al. Reduction of cerebellar glucose metabolism in advanced Alzheimer's disease. J. Nucl. Med. 1997 38 : 925 928.