Aflatoxin G1 reduces the molecular expression of HLA-I, TAP-1 and LMP-2 of adult esophageal epithelial cells in vitro

Toxicology Letters

Volumn 195, Issue 2-3, 2010, Pages 169-173

  Li, Zengning ^a   Cui, Jinfeng ^a   Zhang, Xianghong ^a   Kang, Weijun ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

Aflatoxin G1; HLA I; LMP 2; TAP 1

Indexed keywords

AFLATOXIN G1; CELL PROTEIN; HLA A ANTIGEN; HLA ANTIGEN; HLA ANTIGEN CLASS 1; HLA B ANTIGEN; MESSENGER RNA; PROTEIN LMP 2; TRANSPORTER ASSOCIATED WITH ANTIGEN PROCESSING 1; UNCLASSIFIED DRUG; ABC TRANSPORTER; AFLATOXIN; CARCINOGEN; CYSTEINE PROTEINASE; LMP 2 PROTEIN; LMP-2 PROTEIN; TAP1 PROTEIN, HUMAN;

ADULT; ANTIGEN PRESENTATION; ARTICLE; CARCINOGENESIS; CELL SURFACE; CONTROLLED STUDY; EPITHELIUM CELL; ESOPHAGUS MUCOSA; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IMMUNOSURVEILLANCE; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN STABILITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE; WESTERN BLOTTING; CYTOLOGY; DRUG EFFECT; ESOPHAGUS; METABOLISM;

ASPERGILLUS FLAVUS; FUNGI;

ADULT; AFLATOXINS; ATP-BINDING CASSETTE TRANSPORTERS; CARCINOGENS; CYSTEINE ENDOPEPTIDASES; EPITHELIAL CELLS; ESOPHAGUS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HUMANS;

EID: 77952548343     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2010.03.1118     Document Type: Article

References (31)

1. Al-Bader M.D., El-Abdallah A.A., Redzic Z.B. Ontogenic profile of estrogen receptor alpha and beta mRNA and protein expression in fetal rat brain. Neurosci. Lett. 2008, 440(3):222-226.
2. Choy M.K., Movassagh M., Bennett M.R., Foo R.S. PKB/Akt activation inhibits p53-mediated HIF1A degradation that is independent of MDM2. J. Cell. Physiol. 2010, 222(3):635-639.
3. Doyle A., Martin W.J., Funa K., et al. Markedly decreased expression of class I histocompatibility antigens, protein, and mRNA in human small-cell lung cancer. J. Exp. Med. 1985, 161:1135-1151.
4. Fine C.I., Han C.D., Sun X., et al. Tobacco reduces membrane HLA class I that is restored by transfection with transporter associated with antigen processing 1 cDNA. J. Immunol. 2002, 169(10):6012-6019.
5. Huang X.H., Zhang X.H., Li Y.H., et al. Experimental lung carcinogenic in vivo study of aflatoxin G1 in NIH mice. Zhonghua Bing Li Xue Za Zhi 2004, 33(3):260-263.
6. Hosch S.B., Meyer A.J., Schneider C., et al. Expression and Prognostic Significance of HLA Class I, ICAM, and Tumor Infiltrating Lymphocytes in Esophageal Cancer. J. Gastrointest. Surg. 1997, 1(4):316-323.
7. Hirata S., Yamazaki K., Kubo Y., et al. DNA content analysis and expression of human leukocyte antigen on esophageal cancer. Rinsho Byori. 1995, 43(3):227-232.
8. International Agency for Research on Cancer (IARC) Aflatoxins. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans 1993, vol. 82. IARC Press, Lyon, France, pp. 171-230.
9. Johnson D.R. Locus-specific constitutive and cytokine-induced HLA class I gene expression. J. Immunol. 2003, 170(4):1894-1902.
10. Kritsch K.R., Murali S., Adamo M.L., Ney D.M. Dexamethasone decreases serum and liver IGF-I and maintains liver IGF-I mRNA in parenterally fed rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2002, 282(2):R528-R536.
11. Kutsch O., Vey T., Kerkau T., et al. HIV type I abrogates TAP mediated transport of antigenic pep tides p resented by MHC class I. Transporter associated with antigen presentation. AIDS Res. Hum. Retroviruses 2002, 18(17):1319-1325.
12. Mehta A.M., Jordanova E.S., Kenter G.G., et al. Association of antigen processing machinery and HLA class I defects with clinicopathological outcome in cervical carcinoma. Cancer Immunol. Immunother. 2008, 57:197-206.
13. Meissner M., Reichert T.E., Kunkel M., et al. Defects in the human leukocyte antigen class I antigen-processing machinery in head and neck squamous cell carcinoma: association with clinical outcome. Clin. Cancer Res. 2005, 11:2552-2560.
14. Ogino T., Shigyo H., Ishii H., et al. HLA class I antigen down-regulation in primary laryngeal squamous cell carcinoma lesions as a poor prognostic marker. Cancer Res. 2006, 66:9281-9289.
15. Paterson A.C., Sciot R., Kew M.C., et al. HLA expression in human hepatocellular carcinoma. Br. J. Cancer 1988, 57:369-373.
16. Pamer E., Cresswell P. Mechanisms of MHC class I-restricted antigen processing. Annu. Rev. Immunol. 1998, 16:323-358.
17. Pokharel Y.R., Kim N.D., Han H.K., Oh W.K., Kang K.W. Increased ubiquitination of multidrug resistance 1 by ginsenoside Rd. Nutr. Cancer. 2010, 62(2):252-259.
18. 1 in Aspergillus parasiticus. Biosci. Biotechnol. Biochem. 2007, 71(9):2329-2332.
19. Samudio-Ruiz S.L., Allan A.M., Sheema S., Caldwell K.K. Hippocampal N-methyl-d-aspartate receptor subunit expression profiles in a mouse model of prenatal alcohol exposure. Alcohol Clin. Exp. Res. 2010, 34:342-353.
20. Shen H.T., Zhang X.H., Huang X.H. Histogenesis of lung adenocarcinoma induced by oral administration of mycotoxins in mice. Wei Sheng Yan Jiu 2005, 34:341-344.
21. Sun X.M., Zhang X.H., Wang H.Y. Effects of sterigmatocystin, deoxynivalenol and aflatoxin G1 on apoptosis of human peripheral blood lymphocytes in vitro. Biomed. Environ. Sci. 2002, 15:145-152.
22. Van den Ingh H.F., Ruiter D.J., Griffioen G., et al. HLA antigens in colorectal tumours-low expression of HLA class I antigens in mucinous colorectal carcinomas. Br. J. Cancer 1987, 55:125-130.
23. Vambutas A., DeVoti J., Pinn W., et al. Interaction of human pap illomavirus type 11 E7 protein with TAP2 results in the reduction of ATP dependent peptide transport. Clin. Immunol. 2001, 101:94-99.
24. Wang H., Sun X., Zhang X. Effect of deoxynivalenol and aflatoxin G1 on apoptosis of human blood lymphocytes in vitro. Wei Sheng Yan Jiu 1999, 28:102-104.
25. Xing L.X., Zhang X.H., Li Y.H., et al. The Effect of Sterigmatocystin on the HLA-I Molecule Expression of the Mononuclear Cell Surface of the Human Peripheral Blood. Hyg. Res. 2005, 4:454-456.
26. Xing L.X., Zhang X.H., Li Y.H., et al. The effect of sterigmatocystin on the TAP1 and LMP2 gene expression of the mononuclear cell of the human peripheral blood. China Tumor Clinic. 2004, 31(4):189-192.
27. Xing L.X., Shen H.T., Li Y.H., et al. The effect of fumonisin B1 on the HLA-I molecule expression of the mononuclear cell surface of the human peripheral blood. Cell Mol. Immunol. J. 2007, 23:794-796.
28. Xing L.X., Zhang X.H., Li Y.H., et al. The effect of fumonisin B1 on the expression of the antigen processing relative transporter of the mononuclear cell of the human peripheral blood. J. Cell Biol. 2007, 29:609-612.
29. Zeinieh M.P., Talhouk R.S., El-Sabban M.E., et al. Differential expression of hippocampal connexins after acute hypoxia in the developing brain. Brain Dev. 2009, Dec 22.[Epub ahead of print]. 10.1016/j.braindev.2009.11.003.
30. Zhou B.J., Li Y.H., Zhang X.H., et al. The effect of vitamin on the deoxynivalenol-Induced HLA-I-expression-inhibiting role of the mononuclear cell. Chin. Prev. Med. J. 2006, 40:314-318.
31. Zhang X.H., Xie T.X., Li S.S., et al. Contamination of fungi and mycotoxins in foodstuffs in high risk area of esophageal cancer. Biomed. Environ. Sci. 1998, 1:140-146.