Role of the Fas pathway in Pseudomonas aeruginosa keratitis

Investigative Ophthalmology and Visual Science

Volumn 51, Issue 5, 2010, Pages 2537-2547

  Zhou, Zimei ^a   Wu, Minhao ^a   Barrett, Ronald P ^a   McClellan, Sharon A ^a   Zhang, Yunfan ^a   Hazlett, Linda D ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; FAS ANTIGEN; FAS LIGAND; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 2; NITRITE; PROTEIN BAX; PROTEIN BCL 2; TUMOR NECROSIS FACTOR ALPHA; APOPTOSIS REGULATORY PROTEIN; CYTOKINE; FAS PROTEIN, MOUSE; FASL PROTEIN, MOUSE; MESSENGER RNA; NOS2 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BACTERIAL COUNT; BACTERIAL INFECTION; BACTERIAL KERATITIS; CONTROLLED STUDY; CORNEA PERFORATION; CYTOKINE PRODUCTION; DISEASE EXACERBATION; FEMALE; IN VITRO STUDY; INFECTION RESISTANCE; INFECTION SENSITIVITY; KERATITIS; MOUSE; NEUTROPHIL COUNT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PSEUDOMONAS AERUGINOSA; WILD TYPE; ANIMAL; BACTERIAL EYE INFECTION; BAGG ALBINO MOUSE; C57BL MOUSE; CONFOCAL MICROSCOPY; CORNEA ULCER; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; IMMUNOLOGY; LEUKOCYTE COUNT; MACROPHAGE ACTIVATION; METABOLISM; MICROBIOLOGY; MOUSE MUTANT; NEUTROPHIL; NICK END LABELING; PERITONEUM MACROPHAGE; PHYSIOLOGY; PSEUDOMONAS INFECTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; ANTIGENS, CD95; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; COLONY COUNT, MICROBIAL; CORNEAL ULCER; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; EYE INFECTIONS, BACTERIAL; FAS LIGAND PROTEIN; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; IN SITU NICK-END LABELING; LEUKOCYTE COUNT; MACROPHAGE ACTIVATION; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; NEUTROPHILS; NITRIC OXIDE SYNTHASE TYPE II; NITRITES; PSEUDOMONAS INFECTIONS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 77952529478     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.09-4152     Document Type: Article

References (41)

1. Hazlett LD. Corneal response to Pseudomonas aeruginosa infection. Prog Retin Eye Res. 2004;23:1-30.
2. Mondino BJ, Weissman BA, Farb MD, Pettit TH. Corneal ulcers associated with daily-wear and extended-wear contact lenses. Am J Ophthalmol. 1986;102:58-65.
3. Rattanatam TW, Heng WJ, Rapuano CJ, Laibson RR, Cohen EJ. Trends in contact lens-related corneal ulcers. Cornea. 2001;20: 290-294.
4. Szliter EA, Lighvani S, Barrett RP, Hazlett LD. Vasoactive intestinal peptide balances pro-and anti-inflammatory cytokines in the Pseudomonas aeruginosa-infected cornea and protects against corneal perforation. J Immunol. 2007;178:1105-1114.
5. Zhou Z, Barrett RP, McClellan SA, et al. Substance P delays apoptosis, enhancing keratitis after Pseudomonas aeruginosa infection. Invest Ophthalmol Vis Sci. 2008;49:4458-4467.
6. Steller H. Mechanisms and genes of cellular suicide. Science. 1995; 267:1445-1449.
7. Tibbetts MD, Zheng L, Lenardo MJ. The death effector domain protein family: regulators of cellular homeostasis. Nat Immunol. 2003;4:404-409.
8. Grassme H, Kirschnek S, Riethmueller J, et al. CD95/CD95 ligand interactions on epithelial cells in host defense to Pseudomonas aeruginosa. Science. 2000;20:527-530.
9. Alaoui-El-Azher M, Jia J, Lian W, Jin S. ExoS of Pseudomonas aeruginosa induces apoptosis through a Fas receptor/caspase 8-independent pathway in HeLa cells. Cell Microbiol. 2006;8:326-338.
10. Shi C, Wolfe J, Russell JQ, et al. Fas ligand deficiency impairs host inflammatory response against infection with the spirochete Borrelia burgdorferi. Infect Immun. 2006;74:1156-60.
11. Hazlett LD, Moon MM, Strejc M, Berk RS. Evidence for Nacetylmannosamine as an ocular receptor for P. aeruginosa adherence to scarified cornea. Invest Ophthalmol Vis Sci. 1987; 28:1978-1985.
12. Kernacki KA, Barrett RP, Hobden JA, Hazlett LD. Macrophage inflammatory protein-2 is a mediator of polymorphonuclear neutrophil influx in ocular bacterial infection. J Immunol. 2000;164: 1037-1045.
13. McClellan SA, Zhang Y, Barrett RP, Hazlett LD. Substance P promotes susceptibility to Pseudomonas aeruginosa keratitis in resistant mice: anti-inflammatory mediators downregulated. Invest Ophthalmol Vis Sci. 2008;49:1502-1511.
14. Hazlett LD, McClellan SA, Barrett RP, Liu J, Zhang Y, Lighvani S. Spantide I decreases type I cytokines, enhances IL-10, and reduces corneal perforation in susceptible mice after Pseudomonas aeruginosa infection. Invest Ophthalmol Vis Sci. 2007;48:797-807.
15. Huang X, Du W, Barrett RP, Hazlett LD. ST2 is essential for Th2 responsiveness and resistance to Pseudomonas aeruginosa keratitis. Invest Ophthalmol Vis Sci. 2007;48:4626-4633.
16. Kernacki KA, Goebel DJ, Poosch MS, LD. Hazlett. Early cytokine and chemokine gene expression during Pseudomonas aeruginosa corneal infection in mice. Infect Immun. 1998;66:376-379.
17. Williams RN, Paterson CA. PMN accumulation in aqueous humor and iris-ciliary body during intraocular inflammation. Invest Ophthalmol Vis Sci. 1984;25:105-108.
18. Williams RN, Paterson CA, Eakins KE, Bhattacherjee P. Quantification of ocular inflammation: evaluation of polymorphonuclear leucocyte infiltration by measuring myeloperoxidase activity. Curr Eye Res. 1982;2:465-470.
19. McClellan SA, Lighvani S, Hazlett LD. IFN-gamma: regulation of nitric oxide in the P. aeruginosa-infected cornea. Ocul Immunol Inflamm. 2006;14:21-28.
20. Zhang Y, Gabriel MM, Mowrey-McKee MF, Barrett RP, McClellan S, Hazlett LD. Rat silicone hydrogel contact lens model: effects of high-versus low-Dk lens wear. Eye Contact Lens. 2008;34:306-311.
21. McClellan SA, Huang X, Barrett RP, van Rooijen N, Hazlett LD. Macrophages restrict Pseudomonas aeruginosa growth, regulate polymorphonuclear neutrophil influx, and balance pro-and antiinflammatory cytokines in BALB/c mice. J Immunol. 2003;170: 5219-5227.
22. Allenbach C, Zufferey C, Perez C, Launois P, Mueller C, Tacchini-Cottier F. Macrophages induce neutrophil apoptosis through membrane TNF, a process amplified by Leishmania major. J Immunol. 2006;11:6656-6664.
23. Bockmann S, Seep J, Jonas L. Delay of neutrophil apoptosis by the neuropeptide substance P: involvement of caspase cascade. Peptides. 2001;22:661-670.
24. Engelbert M, Gilmore MS. Fas ligand but not complement is critical for control of experimental Staphylococcus aureus endophthalmitis. Invest Ophthalmol Vis Sci. 2005;46:2479-2486.
25. Niederkorn JY, Chiang EY, Ungchusri T, Stroynowski I. Expression of a nonclassical MHC class Ib molecule in the eye. Transplantation. 1999;68:1790-1799.
26. Fecho K, Cohen PL. Fas ligand (gld)-and Fas (lpr)-deficient mice do not show alterations in the extravasation or apoptosis of inflammatory neutrophils. J Leukoc Biol. 1998;64:373-383.
27. Li P, Nijhawan D, Budihardjo I, et al. Cytochrome c and dATPdependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell. 1997;91:479-489.
28. Liu X, Kim CN, Yang J, Jemmerson R, Wang X. Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell. 1996;86:147-157.
29. Zou H, Henzel WJ, Liu X, Lutschg A, Wang X. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell. 1997;90:405-413.
30. Hengartner MO, Ellis RE, Horvitz HR. Caenorhabditis elegans gene ced-9 protects cells from programmed cell death. Nature. 1992;356:494-499.
31. Korsmeyer SJ. Bcl-2 initiates a new category of oncogenes: regulators of cell death. Blood. 1992;80:879-886.
32. Vaux DL, Weissman IL, Kim SK. Prevention of programmed cell death in Caenorhabditis elegans by human Bcl-2. Science. 1992; 258:1955-1957.
33. Gregory MS, Saff RR, Marshak-Rothstein A, Ksander BR. Control of ocular tumor growth and metastatic spread by soluble and membrane Fas ligand. Cancer Res. 2007;67:11951-11958.
34. Morisette C, Francoeur C, Darmond-Zwaig C, Gervais F. Lung phagocyte bactericidal function in strains of mice resistant and susceptible to Pseudomonas aeruginosa. Infect Immun. 1996;64: 4984-4992.
35. Hazlett LD, Rudner XL, McClellan SA, Barrett RP, Lighvani S. Role of IL-12 and IFN-gamma in Pseudomonas aeruginosa corneal infection. Invest Ophthalmol Vis Sci. 2002;43:419-424.
36. Carmona EM, Vassallo R, Vuk-Pavlovic Z, Standing JE, Kottom TJ, Limper AH. Pneumocystis cell wall beta-glucans induce dendritic cell costimulatory molecule expression and inflammatory activation through a Fas-Fas ligand mechanism. J Immunol. 2006;177: 459-467.
37. Delgado M, Martinez C, Pozo D, et al. Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activation polypeptide (PACAP) protect mice from lethal endotoxemia through the inhibition of TNF-α and IL-6. J Immunol. 1999;162: 1200-1205.
38. Laskin DL, Pendino KJ. Macrophages and inflammatory mediators in tissue injury. Annu Rev Pharmacol Toxicol. 1995;35:655-677.
39. O'Connell J. Immune privilege or inflammation? The paradoxical effects of Fas ligand. Arch Immunol Ther Exp (Warsz). 2000;48: 73-79.
40. Altemeier WA, Zhu X, Berrington WR, Harlan JM, Liles WC. Fas (CD95) induces macrophage proinflammatory chemokine production via a MyD88-dependent, caspase-independent pathway. J Leukoc Biol. 2007;82:721-728.
41. Chung CS, Song GY, Lomas J, Simms HH, Chaudry IH, Ayala A. Inhibition of Fas/Fas ligand signaling improves septic survival: differential effects on macrophage apoptotic and functional capacity. J Leukoc Biol. 2003;74:344-351.