Improving rheological characteristics of hydrophilic ointment base by treatment with a high-pressure wet-type jet mill

Drug Development and Industrial Pharmacy

Volumn 36, Issue 6, 2010, Pages 625-631

  Nishikawa, Masato ^a   Onuki, Yoshinori ^a   Okuno, Yoshihide ^b   Takayama, Kozo ^a  

^a HOSHI UNIVERSITY   (Japan)

^b Ikeda Mohando Co Ltd   (Japan)

Author keywords

High pressure wet type jet mill; Hydrophilic ointment base; Oil droplet size; Thixotropy; Viscosity

Indexed keywords

OINTMENT BASE;

ARTICLE; DEVICE; DRUG FORMULATION; EMULSION; FLOW KINETICS; HYDROPHILICITY; HYSTERESIS; PRESSURE; SCANNING ELECTRON MICROSCOPY; SHEAR RATE; SHEAR STRESS; TEMPERATURE; THIXOTROPY; VISCOSITY; WET TYPE JET MILL;

CHEMISTRY, PHARMACEUTICAL; OINTMENT BASES; PRESSURE; RHEOLOGY; WATER;

EID: 77952524917     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639040903406126     Document Type: Article

References (18)

1. Floury J, Desrumaux A, Lardieres J. (2000). Effect of high-pressure homogenization on droplet size distributions and rheological properties of model oil-in-water emulsions. Innov. Food Sci Emerg, 1:127-34.
2. Cohen, D. (2005). High-shear mixing. Don't fall victim to common misconceptions. Chem Eng, 112:46-51.
3. Fradette L, Brocart B, Tanguy PA. (2007). Comparison of mixing technologies for the production of concentrated emulsions. Chem Eng Res Des, 85:1553-60.
4. Jafari SM, Assadpoor E, He Y, Bhandari B. (2008). Re-coalescence of emulsion droplets during high-energy emulsification. Food Hydrocolloid, 22:1191-202.
5. Silva CM, Ribeiro AJ, Figueiredo IV, Goncalves AR, Veiga F. (2006). Alginate microspheres prepared by internal gelation: Development and effect on insulin stability. Int J Pharm, 311:1-10.
6. Guerrero DQ, Esquivel DT, Quintanar AG, Allemann E, Doelker E. (2005). Adaptation and optimization of the emulsificationdiffusion technique to prepare lipidic nanospheres. Eur J Pharm Sci, 26:211-8.
7. Tanaka K, Ibe H, Kumazawa H. (2003). Submicrometer size emulsification using a high pressure wet-type jet mill. Kagaku Kogaku Ronbunshu, 29:740-7.
8. Tanaka K, Muvuchi N, Kumazawa H. (2004). Effect of dispersed phase viscosity and volume fraction on submicrometer size oilin-water emulsion formation using a high pressure wet-type jet mill. Kagaku Kogaku Ronbunshu, 30:186-93.
9. Seekkuarachchi IN, Tanaka K, Kumazawa H. (2006). Formation and characterization of submicrometer oil-in-water (o/w) emulsions, using high-energy emulsification. Ind Eng Chem Res, 45:372-90.
10. Seekkuarachchi IN, Kumazawa H. (2006). Production of submicrometer size o/w emulsions using a high-pressure wet-type jet mill. Chem Eng Comm, 193:501-25.
11. Seekkuarachchi IN, Tanaka K, Kumazawa H. (2008). Dispersion mechanism of nanoparticulate aggregates using a high pressure wet-type jet mill. Chem Eng Sci, 63:2341-66.
12. Barnes HA. (1994). Rheology of emulsions: A review. Colloid Surf A, 91:89-95.
13. Korhonen M, Niskanen H, Kiesvaara J, Yliruusi J. (2000). Determination of optimal combination of surfactants in creams using rheology measurements. Int J Pharm, 197:143-51.
14. Rajinder P. (1996). Effect of droplet size on the rheology of emulsions. AICHE J, 41:3181-90.
15. Rajinder P. (1998). A novel method to correlate emulsion viscosity data. Colloid Surf A, 137:275-86.
16. Levy G. (1962). Rheology of thixotropic montmorillonite dispersions. I. Changes on aging of plain and polysorbate 80 containing dispersions. J Pharm Sci, 51:947-51.
17. Demachi H, Matsui O, Abo H, Tatsu H. (2000). Simulation model based on non-Newtonian fluid mechanics applied to the evaluation of the embolic effect of emulsions iodized oil and anticancer drug. Cardiovasc Intervent Radiol, 23:285-90.
18. Kirsanov EA, Remizov SV. (1999). Application of the Casson model to thixotropic waxy crude oil. Rheol Acta, 38:172-6.