In vitro bone growth responds to local mechanical strain in three-dimensional polymer scaffolds

Journal of Biomechanics

Volumn 43, Issue 4, 2010, Pages 733-739

  Baas, Elbert ^a   Kuiper, Jan Herman ^a   Yang, Ying ^a   Wood, Mairead A ^a   El Haj, Alicia J ^a  

^a KEELE UNIVERSITY   (United Kingdom)

Author keywords

In vitro skeletal tissue engineering; Local surface strain; Micro computed tomography; Polymer scaffolds; Tissue mineralization

Indexed keywords

BIOLOGICAL RESPONSE; BONE CELLS; BONE FORMATION; BONE GROWTH; BONE TISSUE; BONE TISSUE REGENERATION; CT IMAGE; DESIGN OPTIMISATION; HETEROGENEOUS STRAIN; IN-VITRO; IN-VIVO; LOCAL AVERAGE; LOCAL SURFACES; MECHANICAL STIMULATION; MECHANICAL STRAIN; MICROCOMPUTED TOMOGRAPHY; MINERALIZED NODULES; POLY L LACTIC ACID; POLYMER SCAFFOLDS; POROUS SCAFFOLD; PRINCIPAL STRAIN; STATIC CONDITIONS; THREEDIMENSIONAL (3-D); TISSUE REGENERATION;

BONE; COMPUTERIZED TOMOGRAPHY; LACTIC ACID; POLYMERS; STRAIN; THREE DIMENSIONAL; TISSUE;

SCAFFOLDS (BIOLOGY);

POLYLACTIC ACID; POLYMER; TISSUE SCAFFOLD; LACTIC ACID;

ANIMAL CELL; ARTICLE; BONE CELL; BONE GROWTH; BONE REGENERATION; CELL CULTURE; COMPRESSION; CONTROLLED STUDY; CORRELATION ANALYSIS; FINITE ELEMENT ANALYSIS; IMAGE ANALYSIS; IN VITRO STUDY; MECHANICAL STIMULATION; MECHANICAL STRESS; MICRO-COMPUTED TOMOGRAPHY; NONHUMAN; POROSITY; PRIORITY JOURNAL; RAT; STRESS STRAIN RELATIONSHIP; SURFACE PROPERTY; ANIMAL; BIOLOGICAL MODEL; BONE DEVELOPMENT; BONE MINERALIZATION; CELL PROLIFERATION; CHEMISTRY; COMPUTER SIMULATION; CYTOLOGY; INSTRUMENTATION; MECHANOTRANSDUCTION; OSTEOBLAST; PHYSIOLOGY; TISSUE REGENERATION;

ANIMALS; BONE DEVELOPMENT; CALCIFICATION, PHYSIOLOGIC; CELL PROLIFERATION; CELLS, CULTURED; COMPUTER SIMULATION; GUIDED TISSUE REGENERATION; LACTIC ACID; MECHANOTRANSDUCTION, CELLULAR; MODELS, BIOLOGICAL; OSTEOBLASTS; OSTEOGENESIS; POLYMERS; RATS; STRESS, MECHANICAL; TISSUE SCAFFOLDS;

EID: 77952522235     PISSN: 00219290     EISSN: 18732380     Source Type: Journal    
DOI: 10.1016/j.jbiomech.2009.10.016     Document Type: Article

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