Role of epidermal growth factor and its receptor family in ocular surface wound healing

Chinese Journal of Ophthalmology

Volumn 43, Issue 10, 2007, Pages 953-956

  Liu, Yang ^a   Liu, Zu Guo ^a  

^a XIAMEN UNIVERSITY   (China)

Author keywords

Cornea; Epidermal growth factor; Receptor, epidermal growth factor; Wound healing

Indexed keywords

EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR;

EYE INJURY; HUMAN; PHYSIOLOGY; REVIEW; WOUND HEALING;

EPIDERMAL GROWTH FACTOR; EYE INJURIES; HUMANS; RECEPTOR, EPIDERMAL GROWTH FACTOR; WOUND HEALING;

EID: 77952479291     PISSN: 04124081     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (38)

1. Harris RC, Chung E, Coffey RJ. EGF receptor ligands. Exp Cell Res, 2003, 284: 2-13.
2. Bogdan S, Klambt C. Epidermal growth factor receptor signaling. Curr Biol, 2001, 11: 292-295.
3. Strachan L, Murison JG, Prestidge RL, et al. Cloning and biological activity of epigen, a novel member of the epidermal growth factor superfamily. J Biol Chem, 2001, 276: 18625-18671.
4. Dartt DA. Interaction of EGF family growth factors and neurotransmitters in regulating lacrimal gland secretion. Exp Eye Res, 2004, 78: 337-345.
5. Liu Z, Carvajal M, Carraway CA, et al. Expression of the receptor tyrosine kinases, epidermal growth factor receptor, ErbB2, and ErbB3, in human ocular surface epithelia. Comea, 2001, 20: 81-85.
6. Dartt DA. Regulation of lacrimal gland secretion by neurotransmitters and the EGF family of growth factors. Exp Eye Res, 2001, 73: 741-752.
7. Arango ME, Li P, Komatsu M, et al. Production and localization of Muc4/sialomucin complex and its receptor tyrosine kinase ErbB2 in the rat lacrimal gland. Invest Ophthalmol Vis Sci, 2001, 42: 2749-2756.
8. Swan JS, Arango ME, Carothers Carraway CA, et al. An ErbB2-Muc4 complex in rat ocular surface epithelia. Curr Eye Res, 2002, 24: 397-402.
9. Pflugfelder SC, Liu Z, Monroy D, et al. Detection of sialomucin complex (MUC4) in human ocular surface epithelium and tear fluid. Invest Ophthalmol Vis Sci, 2000, 41: 1316-1326.
10. Wilson SE, Chen L, Mohan RR, et al. Expression of HGF, KGF, EGF and receptor messenger RNAs following corneal epithelial wounding. Exp Eye Res, 1999, 68: 377-397.
11. Imanishi J, Kamiyama K, Iguchi I, et al. Growth factors: importance in wound healing and maintenance of transparency of the cornea. Prog Retin Eye Res, 2000, 19: 113-129.
12. Lee JS, Liu JJ, Hong JW, et al. Differential expression analysis by gene array of cell cycle modulators in human corneal epithelial cells stimulated with epidermal growth factor (EGF), hepatocyte growth factor (HGF), or keratinocyte growth factor (KGF). Curr Eye Res, 2001, 23: 69-76.
13. Nakamura M, Nishida T. Potentiation by cyclic AMP of the stimulatory effect of epidermal growth factor on corneal epithelial migration. Cornea, 2003, 22: 355-358.
14. Song QH, Singh RP, Trinkaus-Randall V. Injury and EGF mediate the expression of a6B4 integrin subunits in corneal epithelium. J Cell Biochem, 2001, 80: 397-414.
15. Song QH, Gong H, Trinkaus-Randall V. Role of epidermal growth factor and epidermal growth factor receptor on hemidesmosome complex formation and integrin subunit B4. Cell Tissue Res, 2003, 312: 203-220.
16. Yanai R, Yamada N, Kugimiya N, et al. Mitogenic and antiapoptotic effects of various growth factors on human corneal fibroblasts. Invest Ophthalmol Vis Sci, 2002, 43: 2122-2126.
17. Wilson SE, Mohan RR, Hong JW, et al. The wound healing response after laser in situ keratomileusis and photorefractive keratectomy: elusive control of biological variability and effect on custom laser vision correction. Arch Ophthalmol, 2001, 119; 889-896.
18. Wilson SE, Liang Q, Kim WJ. Lacrimal gland HGF, KGF, and EGF mRNA levels increase after corneal epithelial wounding. Invest Ophthalmol Vis Sci, 1999, 40: 2185-2190.
19. Zieske JD, Takahashi H, Hutcheon AE, et al. Activation of epidermal growth factor receptor during corneal epithelial migration. Invest Ophthalmol Vis Sci, 2000, 41: 1346-1355.
20. Block ER, Matela AR, SundarRaj N, et al. Wounding induces motility in sheets of corneal epithelial cells through loss of spatial constraints: role of heparin-binding epidermal growth factor-like growth factor signaling. J Biol Chem, 2004, 279; 24307-24312.
21. Iwamoto R, Mekada E. Heparin-binding EGF-like growth factor: a juxtacrine growth factor. Cytokine Growth Factor Rev, 2000, 11; 335-344.
22. Xu KP, Ding Y, Ling J, et al. Wound-induced HB-EGF ectodomain shedding and EGFR activation in corneal epithelial cells. Invest Ophthalmol Vis Sci, 2004, 45: 813-820.
23. Schlotzer-Schrehardt U, Kruse FE. Identification and characterization of limbal stem cells. Exp Eye Res, 2005, 81; 247-264.
24. Lu L, Reinach PS, Kao WW. Corneal epithelial wound healing. Exp Biol Med (Maywood), 2001, 226: 653-664.
25. Xu KP, Yin J, Yu FS. SRC-family tyrosine kinases in wound and ligand-induced epidermal growth factor receptor activation in human corneal epithelial cells. Invest Ophthalmol Vis Sci, 2006, 47: 2832-2839.
26. Chandrasekher G, Bazan HE. Corneal epithelial wound healing increases the expression but not long lasting activation of the p85alpha subunit of phosphatidylinositol-3 kinase. Curr Eye Res, 1999, 18: 168-176.
27. Xu KP, Riggs A, Ding Y, et al. Role of ErbB2 in corneal epithelial wound healing. Invest Ophthalmol Vis Sci, 2004, 45: 4277-4283.
28. + waves in epithelial cells. J Cell Sci, 2001, 114; 4185-4195.
29. Yang H, Sun X, Wang Z, et al. EGF stimulates growth by enhancing capacitative calcium entry in corneal epithelial cells. J Membr Biol, 2003, 194; 47-58.
30. Yang H, Mergler S, Sun X, et al. TRPC4 knockdown suppresses epidermal growth factor-induced store-operated channel activation and growth in human corneal epithelial cells. J Biol Chem, 2005, 280: 32230-32237.
31. 1-48 as neonates. Toxicol Sci, 2001, 62: 80-91.
32. Szaflik J, Fryczkowski AW, Liberek I, et al. Corneal wound healing after penetrating keratoplasty with EGF application: experimental studies. Klin Oczna, 1999, 101; 409-416.
33. Kim MJ, Jun RM, Kim WK, et al. Optimal concentration of human epidermal growth factor (hEGF) for epithelial healing in experimental corneal alkali wounds. Curr Eye Res, 2001, 22: 272-279.
34. 2001, 17: 118-121.
35. 2001, 23: 199-201.
36. 2002, 22: 437-438.
37. Kim EY, Gao ZG, Park JS, et al. rhEGF/HP-B-CD complex in poloxamer gel for ophthalmic delivery. Int J Pharm, 2002, 233: 159-167.
38. Klenkler BJ, Griffith M, Becerril C, et al. EGF-grafted PDMS surfaces in artificial cornea applications. Biomaterials, 2005, 26: 7286-7296.