Association between apoliprotein E gene polymorphism and hypercholesterolemic phenotype in maracaibo, Zulia State, Venezuela

American Journal of Therapeutics

Volumn 17, Issue 3, 2010, Pages 330-336

  Arráiz, Nailet ^a   Bermúdez, Valmore ^a   Prieto, Carem ^a   Sánchez, Maria Patricia ^a   Escalona, Carolina ^a   Sanz, Eileen ^a   Rondón, Netxibeth ^a   Reyes, Francia ^a   Velasco, Manuel ^b  

^a UNIVERSIDAD DEL ZULIA   (Venezuela)

^b UNIVERSIDAD CENTRAL DE VENEZUELA   (Venezuela)

Author keywords

ApoE; Cardiovascular disease; Hypercholesterolemia; Lipids profile; Polymorphisms

Indexed keywords

APOLIPOPROTEIN E; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN; LIPID;

ADOLESCENT; ADULT; AGED; ARTICLE; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; DYSLIPIDEMIA; ENZYME CHEMISTRY; FEMALE; GENE FREQUENCY; GENOTYPE; HETEROZYGOTE; HOMOZYGOTE; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTRIGLYCERIDEMIA; LIPID BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN POLYMORPHISM; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; UNIVERSITY; VARIANCE; VENEZUELA;

ADOLESCENT; ADULT; AGED; ALLELES; APOLIPOPROTEIN E2; APOLIPOPROTEIN E3; APOLIPOPROTEIN E4; CHILD; CROSS-SECTIONAL STUDIES; FEMALE; GENE FREQUENCY; HUMANS; HYPERCHOLESTEROLEMIA; MALE; MIDDLE AGED; PHENOTYPE; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; VENEZUELA; YOUNG ADULT;

EID: 77952477692     PISSN: 10752765     EISSN: None     Source Type: Journal    
DOI: 10.1097/MJT.0b013e3181c1235d     Document Type: Article

References (35)

1. Rosamond WD, Chambless LE, Folsom AR, et al. Trends in the incidence of myocardial infarction and in mortality due to coronary heart disease, 1987 to 1994. N Engl J Med. 1998;339:861-867.
2. Guthrie RM. Rising to the challenge of treating high-risk patients. Am J Manag Care. 2006;12(11 suppl): S318-S24.
3. Wood D, De Backer G, Faergeman O, et al. Prevention of coronary heart disease in clinical practice: recommendations of the second joint task force of European and other societies on coronary prevention. Eur Heart J. 1998;19:1434-1503. (Pubitemid 28470470)
4. Karter AJ, Gazzaniga JM, Cohen RD, et al. Ischemic heart disease and stroke mortality in African-American, Hispanic, and non-Hispanic white men and women, 1985 to 1991. West J Med. 1998;169:139-145.
5. Dobson AJ, Evans A, Ferrario M, et al. Changes in estimated coronary risk in the 1980s: data from 38 populations in the WHO MONICA Project. World Health Organization. Monitoring trends and determinants in cardiovascular diseases. Ann Med. 1998;30:199-205.
6. Marenberg ME, Risch N, Berkman LF, et al. Genetic susceptibility to death from coronary heart disease in a study of twins. N Engl J Med. 1994;330:1041-1046.
7. Boer JM, Feskens EJ, Verschuren WM, et al. The joint impact of family history of myocardial infarction and other risk factors on 12-year coronary heart disease mortality. Epidemiology. 1999;10:767-770.
8. Davignon J, Gregg RE, Sing CF Apolipoprotein E polymorphism and atherosclerosis. Arteriosclerosis. 1988;8:1-21.
9. Wilson PW, Schaefer EJ, Larson MG, et al. Apolipoprotein E alleles and risk of coronary disease. A meta-analysis. Arterioscler Thromb Vasc Biol. 1996;16:1250-1255.
10. Cumming AM, Robertson FW. Polymorphism at the apoprotein-E locus in relation to risk of coronary disease. Clin Genet. 1984;25:310-313.
11. ™: online Mendelian inheritance in man. National Center for Biotechnology Information. Available at: http://www.ncbi.nlm.nih.gov.
12. Emi M, Wu LL, Robertson MA, et al. Genotyping and sequence analysis of apolipoprotein E isoforms. Genomics. 1988;3:373-379. Accesed July 20, 2008.
13. Walden CC, Hegele RA. Apolipoprotein E in hyperlip-idemia. Ann Intern Med. 1994;120:1026-1036.
14. Glickman ME, Kao MF Apo-E genotypes and cardiovascular diseases: a sensitivity study using cross-validatory criteria. Biomed J. 2005;47:541-553.
15. Eto M, Watanabe K, Ishii K. A racial difference in apolipoprotein E allele frequencies between the Japanese and Caucasian populations. Clin Genet. 1986;30:422-427.
16. De Knijff P, van den Maagdenberg AM, Frants RR, et al. Genetic heterogeneity of apolipoprotein E and its influence on plasma lipid and lipoprotein levels. Hum Mutat. 1994;4:178-194.
17. *4 frequencies in western Europe. Hum Biol. 1997;69:253-262.
18. *4 a 'thrifty' allele? Ann Hum Genet. 1999;63:301-310.
19. Fernández-Mestre MT, Yehirobi C, Montagnani S, et al. Genetic variability of apolipoprotein E in different populations from Venezuela. Dis Markers. 2005;21:15-19.
20. Grundy SM, Pasternak R, Greenland P, et al. Assessment of cardiovascular risk by use of multiple-risk-factor assessment equations: a statement for healthcare professionals from the American Heart Association and the American College of Cardiology. Circulation. 1999;100:1481-1492. (Pubitemid 29451714)
21. Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucl Acids Res. 1988;16:1215.
22. Hixson JE, Vernier DT. Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI. J Lipid Res. 1990;31:545-548.
23. Kamboh MI, Aston CE, Ferrell RE, et al. Impact of apolipoprotein E polymorphism in determining interin-dividual variation in total cholesterol and low density lipoprotein cholesterol in Hispanics and non-Hispanic whites. Atherosclerosis. 1993;98:201-211.
24. Eichner JE, Dunn ST, Perveen G, et al. Apolipoprotein E polymorphism and cardiovascular disease: a HuGE review. Am J Epidemiol. 2002;155:487-495.
25. Haddy N, De Bacquer D, Chemaly MM, et al. The importance of plasma apolipoprotein E concentration in addition to its common polymorphism on inter-individual variation in lipid levels: results from Apo Europe. Eur J Hum Genet. 2002:10:841-850.
26. Mendes-Lana, A, Pena GG, Freitas SN, et al. Apolipopro-tein E polymorphism in Brazilian dyslipidemic individuals: Ouro Preto Study. Braz J Med Biol Res. 2007;40:49-56.
27. Souza DR, Nakachima L, Biagioni RB, et al. Relevance of apolipoprotein E4 for the lipid profile of Brazilian patients with coronary artery disease. Braz J Med Biol Res. 2007;40:189-197.
28. Volcik KA, Barkley RA, Hutchinson RG, et al. Apolipo-protein E polymorphisms predict low density lipoprotein cholesterol levels and carotid artery wall thickness but not incident coronary heart disease in 12, 491 ARIC study participants. Am J Epidemiol. 2006;164:342-348.
29. Cullen P, Cignarella A, Brennhausen B, et al. Phenotype-dependent differences in apolipoprotein E metabolism and in cholesterol homeostasis in human monocyte-derived macrophages. J Clin Invest. 1998;101:1670-1677.
30. Tan CE, Tai ES, Tan CS, et al. APOE polymorphism and lipid profile in three ethnic groups in the Singapore population. Atherosclerosis. 2003;170:253-260.
31. Frikke-Schmidt R, Nordestgaard BG, Agerholm-Larsen B, et al. Context-dependent and invariant associations between lipids, lipoproteins, and apolipoproteins and apolipoprotein E genotype. J Lipid Res. 2000;41:1812-1822.
32. Shin MH, Kim HN, Cui L, et al. The effect of apolipoprotein E polymorphism on lipid levels in Korean adults. J Korean Med Sci. 2005;20:361-366.
33. Corbo RM, Vilardo T, Ruggeri M, et al. Apolipoprotein E genotype and plasma levels in coronary artery disease. A case-control study in the Italian population. Clin Biochem. 1999;32:217-222.
34. Lussier-Cacan S, Bolduc A, Xhignesse M, et al. Impact of alcohol intake on measures of lipid metabolism depends on context defined by gender, body mass index, cigarette smoking, and apolipoprotein E genotype. Arterioscler Thromb Vasc Biol. 2002;22:824-831.
35. Nicklas BJ, Ferrell RE, Bunyard LB, et al. Effects of apolipoprotein E genotype on dietary-induced changes in high-density lipoprotein cholesterol in obese postmeno-pausal women. Metabolism. 2002;51:853-858.