Characterization of graded multicenter animal spinal cord injury study contusion spinal cord injury using somatosensory-evoked potentials

Spine

Volumn 35, Issue 11, 2010, Pages 1122-1127

  Agrawal, Gracee ^a   Kerr, Candace ^a   Thakor, Nitish V ^a   All, Angelo H ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

BBB locomotor scale; Contusion; NYU MASCIS impactor; Rat; Somatosensory evoked potential (SEP); Spinal cord injury

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR; CONTROLLED STUDY; CONTUSION; ELECTROPHYSIOLOGY; EVOKED SOMATOSENSORY RESPONSE; FEMALE; HINDLIMB; INJURY SCALE; LAMINECTOMY; NONHUMAN; PRIORITY JOURNAL; RAT; SENSITIVITY ANALYSIS; SPINAL CORD INJURY; SPINE;

ANALYSIS OF VARIANCE; ANIMALS; CEREBRAL CORTEX; CONTUSIONS; ELECTRODES, IMPLANTED; EVOKED POTENTIALS, SOMATOSENSORY; FEMALE; HINDLIMB; MOTOR ACTIVITY; RATS; RATS, INBRED F344; RECOVERY OF FUNCTION; SEVERITY OF ILLNESS INDEX; SPINAL CORD INJURIES; THORACIC VERTEBRAE;

EID: 77952423619     PISSN: 03622436     EISSN: 15281159     Source Type: Journal    
DOI: 10.1097/BRS.0b013e3181be5fa7     Document Type: Article

References (27)

1. Fehlings MG, Tator CH, Linden RD. The relationships among the severity of spinal cord injury, motor and somatosensory evoked potentials and spinal cord blood flow. Electroencephalogr Clin Neurophysiol 1989;74:241-59.
2. Sköld C, Levi R, Seiger Å. Spasticity after traumatic spinal cord injury: nature, severity, and location. Arch Phys Med Rehabil 1999;80:1548-57.
3. Bunge RP, Puckett WR, Becerra JL, et al. Observations on the pathology of human spinal cord injury: a review and classification of 22 new cases with details from a case of chronic cord compression with extensive focal demyelination. Adv Neurol 1993;59:75-89.
4. Kakulas BA. A review of the neuropathology of human spinal cord injury with emphasis on special features. J Spinal Cord Med 1999;22:119-24.
5. Fawcett J. Repair of spinal cord injuries: where are we, where are we going? Spinal Cord 2002;40:615-23.
6. Kakulas BA. Neuropathology: the foundation for new treatments in spinal cord injury. Spinal Cord 2004;42:549-63.
7. Holoday JW, Faden AI. Spinal shock and injury: experimental therapeutic approaches. Adv Shock Res 1983;10:95-8.
8. Pearse DD, Marcillo AE, Oudega M, et al. Transplantation of Schwann cells and olfactory ensheathing glia after spinal cord injury: does pretreatment with methylprednisolone and interleukin-10 enhance recovery? J Neurotrauma 2004;21:1223-39.
9. Berrocal Y, Pearse DD, Singh A, et al. Social and environmental enrichment improves sensory and motor recovery after severe contusive spinal cord injury in the rat. J Neurotrauma 2007;24:1761-72.
10. Brösamle C, Huber AB. Cracking the black box - and putting it back together again: animal models of spinal cord injury. Drug Discov Today 2006;3:341-7.
11. Gruner JA. A monitored contusion model of spinal cord injury in the rat. J Neurotrauma 1992;9:123-8.
12. Metz GA, Curt A, van de Meent H, et al. Validation of the weight-drop contusion model in rats: a comparative study of human spinal cord injury. J Neurotrauma 2000;17:1-17.
13. Young W. Spinal cord contusion models. Prog Brain Res 2002;137:231-55.
14. Kearney PA, Ridella SA, Viano DC, et al. Interaction of contact velocity and cord compression in determining the severity of spinal cord injury. J Neurotrauma 1988;5:187-208.
15. Basso DM, Beattie MS, Bresnahan JC. A sensitive and reliable locomotors rating scale for open field testing in rats. J Neurotrauma 1995;12:1-21.
16. Basso DM, Beattie MS, Bresnahan JC. Graded histological and locomotor outcomes after spinal cord contusion using the NYU weight-drop device versus transaction. Exp Neurol 1996;139:244-56.
17. Eidelberg E, Woolf B, Kreinick CJ, et al. Role of the dorsal funiculi in movement control. Brain Res 1976;114:427-38.
18. Loy DN, Magnuson DS, Zhang YP, et al. Both dorsal and ventral spinal cord pathways contribute to overground locomotion in the adult rat. Exp Neurol 2002;177:575-80.
19. Magnuson DS, Trinder TC, Zhang YP, et al. Comparing deficits following excitotoxic and contusion injuries in the thoracic and lumbar spinal cord of the adult rat. Exp Neurol 1999;156:191-204.
20. Dawson GD. Cerebral response to electrical stimulation of peripheral nerve in man. J Neurol Neurosurg Psychiatry 1947;10:137-40.
21. Blight AR, Young W. Central axons in injured cat spinal cord recover electrophysiological function following remyelination by Schwann cells. J Neurol Sci 1989;91:15-34.
22. Grundy BL. Intraoperative monitoring of sensory evoked potentials. In: Nodar RH, Barber C, eds. Evoked Potentials II. Boston, MA: Butterworth; 1984:624.
23. Nuwer MR. Spinal cord monitoring with somatosensory techniques. J Clin Neurophysiol 1998;15:183-93.
24. Merton PA, Morton HB. Stimulation of the cerebral cortex in the intact human subject. Nature 1980;285:227.
25. de Haan P, Kalkman CJ. Spinal cord monitoring: somatosensory- and motor-evoked potentials. Anesthesiol Clin North America 2001;19:923-45.
26. Sherman DL, Atit MK, Geocadin RG, et al. Diagnostic instrumentation for neurological injury. IEEE Instru Meas Mag 2002;5:28-35.
27. Ditunno JF, Little JW, Tessler A, et al. Spinal shock revisited: a four-phase model. Spinal Cord 2004;42:383-95.