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Volumn 6, Issue 2, 2010, Pages 87-94

Correlation between myoclonus and the 3-glucuronide metabolites in patients treated with morphine or hydromorphone: A pilot study

Author keywords

Hydromorphone; Hydromorphone 3 glucuronide; Morphine; Morphine 3 glucuronide; Myoclonus; Opioid neurotoxicity

Indexed keywords

GLUCURONIDE; HYDROMORPHONE; HYDROMORPHONE 3 GLUCURONIDE; MORPHINE; MORPHINE 3 GLUCURONIDE; UNCLASSIFIED DRUG;

EID: 77952417619     PISSN: 15517489     EISSN: None     Source Type: Journal    
DOI: 10.5055/jom.2010.0008     Document Type: Article
Times cited : (14)

References (45)
  • 1
    • 0034851101 scopus 로고    scopus 로고
    • Myoclonus and its disorders
    • viii
    • Blindauer K: Myoclonus and its disorders. Neurol Clin. 2001; 19(3): 723-734, viii.
    • (2001) Neurol Clin , vol.19 , Issue.3 , pp. 723-734
    • Blindauer, K.1
  • 2
    • 0013678678 scopus 로고    scopus 로고
    • Board INC: USA: University of Wisconsin Pain & Policies Study Group/WHO Collaborating Center
    • Board INC: Global Consumption of Morphine. USA: University of Wisconsin Pain & Policies Study Group/WHO Collaborating Center, 1997.
    • (1997) Global Consumption of Morphine
  • 3
    • 0036365673 scopus 로고    scopus 로고
    • Toxin and drug-induced myoclonus
    • Gordon MF: Toxin and drug-induced myoclonus. Adv Neurol. 2002; 89: 49-76.
    • (2002) Adv Neurol , vol.89 , pp. 49-76
    • Gordon, M.F.1
  • 4
    • 33646281664 scopus 로고
    • Convulsions as a manifestation of acute dextro propoxyphene intoxication
    • Cann HM, Verhulst HL: Convulsions as a manifestation of acute dextro propoxyphene intoxication. Am J Dis Child. 1960; 99: 380-382.
    • (1960) Am J Dis Child , vol.99 , pp. 380-382
    • Cann, H.M.1    Verhulst, H.L.2
  • 5
    • 0014287575 scopus 로고
    • Acute propoxyphene hydrochloride intoxication
    • Gary NE, Maher JF, DeMyttenaere MH, et al.: Acute propoxyphene hydrochloride intoxication. Arch Intern Med. 1968; 121(5): 453-457.
    • (1968) Arch Intern Med , vol.121 , Issue.5 , pp. 453-457
    • Gary, N.E.1    Maher, J.F.2    DeMyttenaere, M.H.3
  • 6
    • 0038067901 scopus 로고
    • Propoxyphene hydrochloride poisoning
    • Qureshi EH: Propoxyphene hydrochloride poisoning. JAMA. 1964; 188: 470-471.
    • (1964) JAMA , vol.188 , pp. 470-471
    • Qureshi, E.H.1
  • 7
    • 0020675827 scopus 로고
    • Central nervous system excitatory effects of meperidine in cancer patients
    • Kaiko RF, Foley KM, Grabinski PY, et al.: Central nervous system excitatory effects of meperidine in cancer patients. Ann Neurol. 1983; 13(2): 180-185.
    • (1983) Ann Neurol , vol.13 , Issue.2 , pp. 180-185
    • Kaiko, R.F.1    Foley, K.M.2    Grabinski, P.Y.3
  • 8
    • 0033303206 scopus 로고    scopus 로고
    • Hiccup and apparent myoclonus after hydrocodone: Review of the opiate-related hiccup and myoclonus literature
    • Lauterbach EC: Hiccup and apparent myoclonus after hydrocodone: Review of the opiate-related hiccup and myoclonus literature. Clin Neuropharmacol. 1999; 22(2): 87-92.
    • (1999) Clin Neuropharmacol , vol.22 , Issue.2 , pp. 87-92
    • Lauterbach, E.C.1
  • 10
    • 0028829011 scopus 로고
    • Dantrolene treatment of opioid-induced myoclonus
    • Mercadante S: Dantrolene treatment of opioid-induced myoclonus. Anesth Analg. 1995; 81(6): 1307-1308.
    • (1995) Anesth Analg , vol.81 , Issue.6 , pp. 1307-1308
    • Mercadante, S.1
  • 11
    • 0031044734 scopus 로고    scopus 로고
    • Acute neuropsychiatric findings in a patient receiving fentanyl for cancer pain
    • DOI 10.1016/S0304-3959(96)03238-1, PII S0304395996032381
    • Bruera E, Pereira J: Acute neuropsychiatric findings in a patient receiving fentanyl for cancer pain. Pain. 1997; 69(1-2): 199-201. (Pubitemid 27081426)
    • (1997) Pain , vol.69 , Issue.1-2 , pp. 199-201
    • Bruera, E.1    Pereira, J.2
  • 12
    • 0014874531 scopus 로고
    • Electrographic effects of diacetylmorphine (heroin) and naloxone in man*1
    • Volavka J, Zaks A, Roubicek J, et al.: Electrographic effects of diacetylmorphine (heroin) and naloxone in man*1. Neuropharmacology. 1970; 9(6): 587-593.
    • (1970) Neuropharmacology , vol.9 , Issue.6 , pp. 587-593
    • Volavka, J.1    Zaks, A.2    Roubicek, J.3
  • 14
    • 0027423331 scopus 로고
    • Myoclonic spasms during treatment with high doses of intravenous morphine in renal failure
    • Sjogren P, Dragsted L, Christensen CB: Myoclonic spasms during treatment with high doses of intravenous morphine in renal failure. Acta Anaesthesiol Scand. 1993; 37(8): 780-782. (Pubitemid 23345800)
    • (1993) Acta Anaesthesiologica Scandinavica , vol.37 , Issue.8 , pp. 780-782
    • Sjogren, P.1    Dragsted, L.2    Christensen, C.B.3
  • 15
    • 0025209851 scopus 로고
    • Myoclonic seizure activity with chronic high-dose spinal opioid administration
    • Parkinson SK, Bailey SL, Little WL, et al.: Myoclonic seizure activity with chronic high-dose spinal opioid administration. Anesthesiology. 1990; 72(4): 743-745.
    • (1990) Anesthesiology , vol.72 , Issue.4 , pp. 743-745
    • Parkinson, S.K.1    Bailey, S.L.2    Little, W.L.3
  • 16
    • 0032958695 scopus 로고    scopus 로고
    • Cerebrospinal fluid and plasma concentrations of morphine, morphine-3-glucuronide, and morphine-6-glucuronide in patients before and after initiation of intracerebroventricular morphine for cancer pain management
    • Miscellaneous Article.
    • Smith MTP, Wright AWEM, Williams BEF, et al.: Cerebrospinal fluid and plasma concentrations of morphine, morphine-3-glucuronide, and morphine-6-glucuronide in patients before and after initiation of intracerebroventricular morphine for cancer pain management. [Miscellaneous Article]. Anesth Analg. 1999; 88(1): 109-116.
    • (1999) Anesth Analg , vol.88 , Issue.1 , pp. 109-116
    • Smith, M.T.P.1    Awem, W.2    Williams, B.E.F.3
  • 17
    • 0027527448 scopus 로고
    • Hyperalgesia and myoclonus in terminal cancer patients treated with continuous intravenous morphine
    • DOI 10.1016/0304-3959(93)90188-U
    • Sjogren P, Jonsson T, Jensen NH, et al.: Hyperalgesia and myoclonus in terminal cancer patients treated with continuous intravenous morphine. Pain. 1993; 55(1): 93-97 (Pubitemid 23300820)
    • (1993) Pain , vol.55 , Issue.1 , pp. 93-97
    • Sjogren, P.1    Jonsson, T.2    Jensen, N.-H.3    Drenck, N.-E.4    Staehelin Jensen, T.5
  • 18
    • 0024970939 scopus 로고
    • Myoclonus associated with treatment with high doses of morphine: The role of supplemental drugs
    • Potter JM, Reid DB, Shaw RJ, et al.: Myoclonus associated with treatment with high doses of morphine: The role of supplemental drugs. BMJ. 1989; 299(6692): 150-153.
    • (1989) BMJ , vol.299 , Issue.6692 , pp. 150-153
    • Potter, J.M.1    Reid, D.B.2    Shaw, R.J.3
  • 19
    • 0027311289 scopus 로고
    • Opioid hyperexcitability: The application of alternate opioid therapy
    • MacDonald N, Der L, Allan S, et al.: Opioid hyperexcitability: The application of alternate opioid therapy. Pain. 1993; 53(3): 353-355.
    • (1993) Pain , vol.53 , Issue.3 , pp. 353-355
    • MacDonald, N.1    Der, L.2    Allan, S.3
  • 20
    • 0035876325 scopus 로고    scopus 로고
    • Hydromorphone-3-glucuronide: A more potent neuro-excitant than its structural analogue, morphine-3-glucuronide
    • Wright AW, Mather LE, Smith MT: Hydromorphone-3-glucuronide: A more potent neuro-excitant than its structural analogue, morphine-3-glucuronide. Life Sci. 2001; 69(4): 409-420.
    • (2001) Life Sci , vol.69 , Issue.4 , pp. 409-420
    • Wright, A.W.1    Mather, L.E.2    Smith, M.T.3
  • 21
    • 0016637598 scopus 로고
    • Antagonism of the convulsant effects of heroin, d-propoxyphene, meperidine, normeperidine and thebaine by naloxone in mice
    • Gilbert PE, Martin WR: Antagonism of the convulsant effects of heroin, d-propoxyphene, meperidine, normeperidine and thebaine by naloxone in mice. J Pharmacol Exp Ther. 1975; 192(3): 538-541.
    • (1975) J Pharmacol Exp Ther , vol.192 , Issue.3 , pp. 538-541
    • Gilbert, P.E.1    Martin, W.R.2
  • 22
    • 0034053670 scopus 로고    scopus 로고
    • Neuroexcitatory effects of morphine and hydromorphone: Evidence implicating the 3-glucuronide metabolites
    • Smith MT: Neuroexcitatory effects of morphine and hydromorphone: Evidence implicating the 3-glucuronide metabolites. Clin Exp Pharmacol Physiol. 2000; 27(7): 524-528.
    • (2000) Clin Exp Pharmacol Physiol , vol.27 , Issue.7 , pp. 524-528
    • Smith, M.T.1
  • 23
    • 0035340444 scopus 로고    scopus 로고
    • Strategies to manage the adverse effects of oral morphine: An evidence-based report
    • Cherny N, Ripamonti C, Pereira J, et al: Strategies to manage the adverse effects of oral morphine: An evidence-based report. J Clin Oncol. 2001; 19(9): 2542-2554.
    • (2001) J Clin Oncol , vol.19 , Issue.9 , pp. 2542-2554
    • Cherny, N.1    Ripamonti, C.2    Pereira, J.3
  • 24
    • 4644289902 scopus 로고    scopus 로고
    • Successful treatment of hydromorphone-induced neurotoxicity and hyperalgesia
    • Chung KS, Carson S, Glassman D, et al.: Successful treatment of hydromorphone-induced neurotoxicity and hyperalgesia. Conn Med. 2004; 68(9): 547-549.
    • (2004) Conn Med , vol.68 , Issue.9 , pp. 547-549
    • Chung, K.S.1    Carson, S.2    Glassman, D.3
  • 25
    • 0029020857 scopus 로고
    • Opioid rotation for toxicity reduction in terminal cancer patients
    • de Stoutz ND, Bruera E, Suarez-Almazor M: Opioid rotation for toxicity reduction in terminal cancer patients. J Pain Symptom Manage. 1995; 10(5): 378-384.
    • (1995) J Pain Symptom Manage , vol.10 , Issue.5 , pp. 378-384
    • De Stoutz, N.D.1    Bruera, E.2    Suarez-Almazor, M.3
  • 26
    • 0025752395 scopus 로고
    • High-performance liquid chromatographic determination of morphine and its 3- and 6-glucuronide metabolites: Improvements to the method and application to stability studies
    • Milne RW, Nation RL, Reynolds GD, et al.: High-performance liquid chromatographic determination of morphine and its 3- and 6-glucuronide metabolites: Improvements to the method and application to stability studies. J Chromatogr. 1991; 565(1-2): 457-464.
    • (1991) J Chromatogr , vol.565 , Issue.1-2 , pp. 457-464
    • Milne, R.W.1    Nation, R.L.2    Reynolds, G.D.3
  • 27
    • 0030879284 scopus 로고    scopus 로고
    • Plasma morphine and glucuronide (M3G and M6G) concentrations in hospice inpatients
    • DOI 10.1016/S0885-3924(97)00020-1, PII S0885392497000201
    • Ashby M, Fleming B, Wood M, et al.: Plasma morphine and glucuronide (M3G and M6G) concentrations in hospice inpatients. J Pain Symptom Manage. 1997; 14(3): 157-167. (Pubitemid 27377599)
    • (1997) Journal of Pain and Symptom Management , vol.14 , Issue.3 , pp. 157-167
    • Ashby, M.1    Fleming, B.2    Wood, M.3    Somogyi, A.4
  • 28
    • 0031752972 scopus 로고    scopus 로고
    • Is development of hyperalgesia, allodynia and myoclonus related to morphine metabolism during long-term administration? Six case histories
    • Sjogren P, Thunedborg LP, Christrup L, et al.: Is development of hyperalgesia, allodynia and myoclonus related to morphine metabolism during long-term administration? Six case histories. Acta Anaesthesiol Scand. 1998; 42(9): 1070-1075.
    • (1998) Acta Anaesthesiol Scand , vol.42 , Issue.9 , pp. 1070-1075
    • Sjogren, P.1    Thunedborg, L.P.2    Christrup, L.3
  • 29
    • 0023798630 scopus 로고
    • Hydromorphone levels and pain control in patients with severe chronic pain
    • Reidenberg MM, Goodman H, Erie H, et al.: Hydromorphone levels and pain control in patients with severe chronic pain. Clin Pharmacol Ther. 1988; 44(4): 376-382.
    • (1988) Clin Pharmacol Ther , vol.44 , Issue.4 , pp. 376-382
    • Reidenberg, M.M.1    Goodman, H.2    Erie, H.3
  • 30
    • 13244269855 scopus 로고    scopus 로고
    • Day-to-day variations during clinical drug monitoring of morphine, morphine-3-glucuronide and morphine-6-glucuronide serum concentrations in cancer patients. a prospective observational study
    • Klepstad P, Hilton P, Moen J, et al.: Day-to-day variations during clinical drug monitoring of morphine, morphine-3-glucuronide and morphine-6-glucuronide serum concentrations in cancer patients. A prospective observational study. BMC Clin Pharmacol. 2004; 4(1): 7.
    • (2004) BMC Clin Pharmacol , vol.4 , Issue.1 , pp. 7
    • Klepstad, P.1    Hilton, P.2    Moen, J.3
  • 31
    • 0030471828 scopus 로고    scopus 로고
    • Concentrations of morphine and morphine metabolites in CSF and plasma during continuous subcutaneous morphine administration in cancer pain patients
    • DOI 10.1016/S0304-3959(96)03102-8, PII S0304395996031028
    • Wolff T, Samuelsson H, Hedner T: Concentrations of morphine and morphine metabolites in CSF and plasma during continuous subcutaneous morphine administration in cancer pain patients. Pain. 1996; 68(2-3):209-216. (Pubitemid 27025877)
    • (1996) Pain , vol.68 , Issue.2-3 , pp. 209-216
    • Wolff, T.1    Samuelsson, H.2    Hedner, T.3
  • 32
    • 0028158255 scopus 로고
    • Concentrations of morphine, morphine-6-glucuronide and morphine-3-glucuronide in serum and cerebrospinal fluid following morphine administration to patients with morphine-resistant pain
    • Goucke CR, Hackett LP, Ilett KF: Concentrations of morphine, morphine-6-glucuronide and morphine-3-glucuronide in serum and cerebrospinal fluid following morphine administration to patients with morphine-resistant pain. Pain.1994; 56(2): 145-149.
    • (1994) Pain , vol.56 , Issue.2 , pp. 145-149
    • Goucke, C.R.1    Hackett, L.P.2    Ilett, K.F.3
  • 33
    • 0029129171 scopus 로고
    • Morphine and morphine metabolite concentrations in cerebrospinal fluid and plasma in cancer pain patients after slow-release oral morphine administration
    • Wolff T, Samuelsson H, Hedner T: Morphine and morphine metabolite concentrations in cerebrospinal fluid and plasma in cancer pain patients after slow-release oral morphine administration. Pain. 1995; 62(2): 147-154.
    • (1995) Pain , vol.62 , Issue.2 , pp. 147-154
    • Wolff, T.1    Samuelsson, H.2    Hedner, T.3
  • 36
    • 0031933116 scopus 로고    scopus 로고
    • Systematic review of factors affecting the ratios of morphine and its major metabolites
    • Faura CC, Collins SL, Moore RA, et al.: Systematic review of factors affecting the ratios of morphine and its major metabolites. Pain. 1998; 74(1): 43-53.
    • (1998) Pain , vol.74 , Issue.1 , pp. 43-53
    • Faura, C.C.1    Collins, S.L.2    Moore, R.A.3
  • 37
    • 0023903827 scopus 로고
    • Influence of renal function on the elimination of morphine and morphine glucuronides
    • Wolff J, Bigler D, Christensen CB, et al.: Influence of renal function on the elimination of morphine and morphine glucuronides. Eur J Clin Pharmacol. 1988; 34(4): 353-357.
    • (1988) Eur J Clin Pharmacol , vol.34 , Issue.4 , pp. 353-357
    • Wolff, J.1    Bigler, D.2    Christensen, C.B.3
  • 38
    • 0028260984 scopus 로고
    • Plasma and cerebrospinal fluid concentrations of morphine and morphine glucuronides after oral morphine. The influence of renal failure
    • D'Honneur G, Gilton A, Sandouk P, et al.: Plasma and cerebrospinal fluid concentrations of morphine and morphine glucuronides after oral morphine. The influence of renal failure. Anesthesiology. 1994; 81(1): 87-93.
    • (1994) Anesthesiology , vol.81 , Issue.1 , pp. 87-93
    • D'Honneur, G.1    Gilton, A.2    Sandouk, P.3
  • 39
    • 0028843621 scopus 로고
    • Steady-state pharmacokinetics of hydromorphone and hydromorphone-3- glucuronide in cancer patients after immediate and controlled-release hydromorphone
    • Hagen N, Thirlwell MP, Dhaliwal HS, et al.: Steady-state pharmacokinetics of hydromorphone and hydromorphone-3-glucuronide in cancer patients after immediate and controlled-release hydromorphone. J Clin Pharmacol. 1995; 35(1): 37-44.
    • (1995) J Clin Pharmacol , vol.35 , Issue.1 , pp. 37-44
    • Hagen, N.1    Thirlwell, M.P.2    Dhaliwal, H.S.3
  • 40
    • 0029076403 scopus 로고
    • Hydromorphone metabolite accumulation in renal failure
    • Babul N, Darke AC, Hagen N: Hydromorphone metabolite accumulation in renal failure. J Pain Symptom Manage. 1995; 10(3): 184-186.
    • (1995) J Pain Symptom Manage , vol.10 , Issue.3 , pp. 184-186
    • Babul, N.1    Darke, A.C.2    Hagen, N.3
  • 41
    • 0027944339 scopus 로고
    • Disappearance of morphine-induced hyperalgesia after discontinuing or substituting morphine with other opioid agonists
    • DOI 10.1016/0304-3959(94)90084-1
    • Sjogren P, Jensen NH, Jensen TS: Disappearance of morphine-induced hyperalgesia after discontinuing or substituting morphine with other opioid agonists. Pain. 1994; 59(2): 313-316. (Pubitemid 24348916)
    • (1994) Pain , vol.59 , Issue.2 , pp. 313-316
    • Sjogren, P.1    Jensen, N.-H.2    Jensen, T.S.3
  • 42
    • 0029049069 scopus 로고
    • Morphine-induced hyperalgesia, allodynia and myoclonus-new side-effects of morphine?
    • Jacobsen LS, Olsen AK, Sjogren P, et al.: [Morphine-induced hyperalgesia, allodynia and myoclonus-new side-effects of morphine?]. Ugeskr Laeger. 1995; 157(23): 3307-3310.
    • (1995) Ugeskr Laeger , vol.157 , Issue.23 , pp. 3307-3310
    • Jacobsen, L.S.1    Olsen, A.K.2    Sjogren, P.3
  • 43
    • 0024368514 scopus 로고
    • Seizures during opioid anesthetic induction - Are they opioid-induced rigidity?
    • Smith NT, Benthuysen JL, Bickford RG, et al.: Seizures during opioid anesthetic induction - Are they opioid-induced rigidity? Anesthesiology. 1989; 71(6): 852-862.
    • (1989) Anesthesiology , vol.71 , Issue.6 , pp. 852-862
    • Smith, N.T.1    Benthuysen, J.L.2    Bickford, R.G.3
  • 44
  • 45
    • 0028902163 scopus 로고
    • Morphine-6-glucuronide concentrations and opioid-related side effects: A survey in cancer patients
    • Tiseo PJ, Thaler HT, Lapin J, et al.: Morphine-6-glucuronide concentrations and opioid-related side effects: A survey in cancer patients. Pain. 1995; 61(1): 47-54.
    • (1995) Pain , vol.61 , Issue.1 , pp. 47-54
    • Tiseo, P.J.1    Thaler, H.T.2    Lapin, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.