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Volumn 88, Issue 1, 1999, Pages 109-116

Cerebrospinal fluid and plasma concentrations of morphine, morphine-3- glucuronide, and morphine-6-glucuronide in patients before and after initiation of intracerebroventricular morphine for cancer pain management

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; MORPHINE; MORPHINE 3 GLUCURONIDE; MORPHINE 6 GLUCURONIDE;

EID: 0032958695     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000539-199901000-00021     Document Type: Article
Times cited : (37)

References (28)
  • 1
    • 0023197399 scopus 로고
    • Intraventricular morphine administration for control of chronic cancer pain
    • Obbens EA, Hill CS, Leavens ME, et al. Intraventricular morphine administration for control of chronic cancer pain. Pain 1987;28:61-8.
    • (1987) Pain , vol.28 , pp. 61-68
    • Obbens, E.A.1    Hill, C.S.2    Leavens, M.E.3
  • 2
    • 0023680628 scopus 로고
    • Intracerebroventricular administration of morphine for control of irreducible cancer pain
    • Lazorthes Y. Intracerebroventricular administration of morphine for control of irreducible cancer pain. Ann N Y Acad Sci 1988;531:123-32.
    • (1988) Ann N Y Acad Sci , vol.531 , pp. 123-132
    • Lazorthes, Y.1
  • 3
    • 0027426759 scopus 로고
    • Intraventricular morphine for intractable pain of advanced cancer
    • Cramond T, Stuart G. Intraventricular morphine for intractable pain of advanced cancer. J Pain Symptom Manage 1993;8: 465-73.
    • (1993) J Pain Symptom Manage , vol.8 , pp. 465-473
    • Cramond, T.1    Stuart, G.2
  • 4
    • 0029957094 scopus 로고    scopus 로고
    • Intraventricular administration of morphine for control of intractable cancer pain in 90 patients
    • Karavelis A, Foroglou G, Selviaridis P, Fountzilas G. Intraventricular administration of morphine for control of intractable cancer pain in 90 patients. Neurosurgery 1996;39:57-61.
    • (1996) Neurosurgery , vol.39 , pp. 57-61
    • Karavelis, A.1    Foroglou, G.2    Selviaridis, P.3    Fountzilas, G.4
  • 5
    • 0029845433 scopus 로고    scopus 로고
    • Comparative efficacy of epidural, subarachnoid, and intracerebroventricular opioids in patients with pain due to cancer
    • Ballantyne JC, Carr DB, Berkey CS, et al. Comparative efficacy of epidural, subarachnoid, and intracerebroventricular opioids in patients with pain due to cancer. Reg Anesth 1996,21:514-6.
    • (1996) Reg Anesth , vol.21 , pp. 514-516
    • Ballantyne, J.C.1    Carr, D.B.2    Berkey, C.S.3
  • 6
    • 0029738663 scopus 로고    scopus 로고
    • The disposition of morphine and its 3- and 6-glucuronide metabolites in humans and animals, and the importance of the metabolites to the pharmacological effects of morphine
    • Milne RW, Nation RL, Somogyi AA. The disposition of morphine and its 3- and 6-glucuronide metabolites in humans and animals, and the importance of the metabolites to the pharmacological effects of morphine. Drug Metab Rev 1996;28:345-472.
    • (1996) Drug Metab Rev , vol.28 , pp. 345-472
    • Milne, R.W.1    Nation, R.L.2    Somogyi, A.A.3
  • 7
    • 0018367544 scopus 로고
    • Morphine derivatives with diminished opiate receptor potency show enhanced central excitatory activity
    • Labella FS, Pinsky C, Havlicek V. Morphine derivatives with diminished opiate receptor potency show enhanced central excitatory activity. Brain Res 1979;174:263-71.
    • (1979) Brain Res , vol.174 , pp. 263-271
    • Labella, F.S.1    Pinsky, C.2    Havlicek, V.3
  • 8
    • 0025006485 scopus 로고
    • Morphine-3-glucuronide: A potent antagonist of morphine analgesia
    • Smith MT, Watt JA, Cramond T. Morphine-3-glucuronide: a potent antagonist of morphine analgesia. Life Sci 1990;47: 579-85.
    • (1990) Life Sci , vol.47 , pp. 579-585
    • Smith, M.T.1    Watt, J.A.2    Cramond, T.3
  • 10
    • 0027527448 scopus 로고
    • Hyperalgesia and myoclonus in terminal cancer patients treated with continuous intravenous morphine
    • Sjogren P, Jonsson T, Jensen NH, et al. Hyperalgesia and myoclonus in terminal cancer patients treated with continuous intravenous morphine. Pain 1993;55:93-7.
    • (1993) Pain , vol.55 , pp. 93-97
    • Sjogren, P.1    Jonsson, T.2    Jensen, N.H.3
  • 11
    • 0026501373 scopus 로고
    • Morphine-3-glucuronide may functionally antagonise morphine-6-glucuronide induced antinociception and ventilatory depression in the rat
    • Gong QL, Hedner J, Bjorkman R, Hedner T. Morphine-3-glucuronide may functionally antagonise morphine-6-glucuronide induced antinociception and ventilatory depression in the rat. Pain 1992;48:249-55.
    • (1992) Pain , vol.48 , pp. 249-255
    • Gong, Q.L.1    Hedner, J.2    Bjorkman, R.3    Hedner, T.4
  • 12
    • 0030131066 scopus 로고    scopus 로고
    • Lack of morphine-6-glucuronide antinociception after morphine treatment: Is morphine-3-glucuronide involved?
    • Faura CC, Olaso MJ, Garcia-Cabanes C, Horga JF. Lack of morphine-6-glucuronide antinociception after morphine treatment: is morphine-3-glucuronide involved? Pain 1996;65: 25-30.
    • (1996) Pain , vol.65 , pp. 25-30
    • Faura, C.C.1    Olaso, M.J.2    Garcia-Cabanes, C.3    Horga, J.F.4
  • 13
    • 0027212338 scopus 로고
    • Lack of effect of morphine-3-glucuronide on the spinal antinociceptive actions of morphine in the rat: An electrophysiological study
    • Hewett K, Dickenson AH, McQuay HJ. Lack of effect of morphine-3-glucuronide on the spinal antinociceptive actions of morphine in the rat: an electrophysiological study. Pain 1993; 53:59-63.
    • (1993) Pain , vol.53 , pp. 59-63
    • Hewett, K.1    Dickenson, A.H.2    McQuay, H.J.3
  • 14
    • 0027374701 scopus 로고
    • Intrathecal morphine-3-glucuronide does not antagonize spinal antinociception by morphine or morphine-6-glucuronide in rats
    • Suzuki N, Kalso E, Rosenberg PJ. Intrathecal morphine-3-glucuronide does not antagonize spinal antinociception by morphine or morphine-6-glucuronide in rats. Eur J Pharmacol 1993; 249:247-50.
    • (1993) Eur J Pharmacol , vol.249 , pp. 247-250
    • Suzuki, N.1    Kalso, E.2    Rosenberg, P.J.3
  • 15
    • 0345521194 scopus 로고    scopus 로고
    • Invasive techniques for neuropathic pain
    • Portenoy RK, Bruera E, eds. New York: Oxford University Press
    • Cramond T. Invasive techniques for neuropathic pain. In: Portenoy RK, Bruera E, eds. Topics in palliative care. vol. 2. New York: Oxford University Press, 1998:63-86.
    • (1998) Topics in Palliative Care , vol.2 , pp. 63-86
    • Cramond, T.1
  • 16
    • 0028230116 scopus 로고
    • Quantitation of morphine, morphine-3-glucuronide and morphine-6-glucuronide in plasma and cerebrospinal fluid using solid-phase extraction and high-performance liquid chromatography with electrochemical detection
    • Wright AWE, Watt JA, Kennedy M, et al. Quantitation of morphine, morphine-3-glucuronide and morphine-6-glucuronide in plasma and cerebrospinal fluid using solid-phase extraction and high-performance liquid chromatography with electrochemical detection. Ther Drug Monit 1994;6:200-8.
    • (1994) Ther Drug Monit , vol.6 , pp. 200-208
    • Wright, A.W.E.1    Watt, J.A.2    Kennedy, M.3
  • 17
    • 0028158255 scopus 로고
    • Concentrations of morphine, morphine-6-glucuronide and morphine-3-glucuronide in serum and cerebrospinal fluid after morphine administration to patients with morphine-resistant pain
    • Goucke CR, Hackett LP, Ilett KF. Concentrations of morphine, morphine-6-glucuronide and morphine-3-glucuronide in serum and cerebrospinal fluid after morphine administration to patients with morphine-resistant pain. Pain 1994;56:145-9.
    • (1994) Pain , vol.56 , pp. 145-149
    • Goucke, C.R.1    Hackett, L.P.2    Ilett, K.F.3
  • 18
    • 0024341553 scopus 로고
    • Dual opioid modulation of the action potential duration of mouse dorsal root ganglion neurons in culture
    • Shen KF, Crain SM, Dual opioid modulation of the action potential duration of mouse dorsal root ganglion neurons in culture. Brain Res 1989;491:227-42.
    • (1989) Brain Res , vol.491 , pp. 227-242
    • Shen, K.F.1    Crain, S.M.2
  • 19
    • 0025086815 scopus 로고
    • Analgesic synergy and improved motor function produced by combinations of mu-delta and mu-kappa opioids
    • Sutters KA, Miaskowski C, Taiwo YO, Levine JD. Analgesic synergy and improved motor function produced by combinations of mu-delta and mu-kappa opioids. Brain Res 1990;530: 290-4.
    • (1990) Brain Res , vol.530 , pp. 290-294
    • Sutters, K.A.1    Miaskowski, C.2    Taiwo, Y.O.3    Levine, J.D.4
  • 20
    • 0019132654 scopus 로고
    • Multiplicative interaction between narcotic agonisms expressed at spinal and supraspinal sites of antinociceptive action as revealed by concurrent intrathecal and intracerebroventricular injections of morphine
    • Yeung JC, Rudy TA. Multiplicative interaction between narcotic agonisms expressed at spinal and supraspinal sites of antinociceptive action as revealed by concurrent intrathecal and intracerebroventricular injections of morphine. J Pharmacol Exp Ther 1980;215:633-42.
    • (1980) J Pharmacol Exp Ther , vol.215 , pp. 633-642
    • Yeung, J.C.1    Rudy, T.A.2
  • 21
    • 0023227229 scopus 로고
    • Explanation for potency of repeated oral doses of morphine?
    • Hanks GW, Hoskin PJ, Aherne GW, et al. Explanation for potency of repeated oral doses of morphine? Lancet 1986;2:723-5.
    • (1986) Lancet , vol.2 , pp. 723-725
    • Hanks, G.W.1    Hoskin, P.J.2    Aherne, G.W.3
  • 22
    • 0026059585 scopus 로고
    • Antinociceptive and ventilatory effects of the morphine metabolites: Morphine-6-glucuronide and morphine-3-glucuronide
    • Gong QL, Hedner T, Hedner J, et al. Antinociceptive and ventilatory effects of the morphine metabolites: morphine-6-glucuronide and morphine-3-glucuronide. Eur J Pharmacol 1991;193:47-56.
    • (1991) Eur J Pharmacol , vol.193 , pp. 47-56
    • Gong, Q.L.1    Hedner, T.2    Hedner, J.3
  • 23
    • 0024350701 scopus 로고
    • Ventilatory effects of fourth cerebroventricular infusions of morphine-6-or morphine-3-glucuronide in the awake dog
    • Pelligrino DA, Riegler FX, Albrecht RF. Ventilatory effects of fourth cerebroventricular infusions of morphine-6-or morphine-3-glucuronide in the awake dog. Anesthesiology 1989;71:936-40.
    • (1989) Anesthesiology , vol.71 , pp. 936-940
    • Pelligrino, D.A.1    Riegler, F.X.2    Albrecht, R.F.3
  • 24
    • 0024369341 scopus 로고
    • Pharmacological characterization of morphine-6β-glucuronide, a very potent morphine metabolite
    • Paul D, Standifer KM, Inturrisi CE, Pasternak GW. Pharmacological characterization of morphine-6β-glucuronide, a very potent morphine metabolite. J Pharmacol Exp Ther 1989;251: 477-83.
    • (1989) J Pharmacol Exp Ther , vol.251 , pp. 477-483
    • Paul, D.1    Standifer, K.M.2    Inturrisi, C.E.3    Pasternak, G.W.4
  • 25
    • 0029022563 scopus 로고
    • Morphine-3-glucuronide: Evidence to support its putative role in the development of tolerance to the antinociceptive effects of morphine in the rat
    • Smith GD, Smith MT. Morphine-3-glucuronide: evidence to support its putative role in the development of tolerance to the antinociceptive effects of morphine in the rat. Pain 1995;62: 51-60.
    • (1995) Pain , vol.62 , pp. 51-60
    • Smith, G.D.1    Smith, M.T.2
  • 26
    • 0029589460 scopus 로고
    • Relationship between morphine analgesia and cortical extracellular fluid levels of morphine and its metabolites in the rat: A microdialysis study
    • Barjavel MJ, Scherrmann JM, Bhargava HN. Relationship between morphine analgesia and cortical extracellular fluid levels of morphine and its metabolites in the rat: a microdialysis study. Br J Pharmacol 1995;116:3205-10.
    • (1995) Br J Pharmacol , vol.116 , pp. 3205-3210
    • Barjavel, M.J.1    Scherrmann, J.M.2    Bhargava, H.N.3
  • 27
    • 0028178398 scopus 로고
    • Morphine-3-glucuronide: Silent regulator of morphine actions
    • Lipkowski AW, Carr DB, Langlade A, et al. Morphine-3-glucuronide: silent regulator of morphine actions. Life Sci 1994; 55:149-54.
    • (1994) Life Sci , vol.55 , pp. 149-154
    • Lipkowski, A.W.1    Carr, D.B.2    Langlade, A.3
  • 28
    • 0030739475 scopus 로고    scopus 로고
    • Effect of prior morphine-3-glucuronide exposure on morphine disposition and antinociception
    • Ouellet DM, Pollack GM. Effect of prior morphine-3-glucuronide exposure on morphine disposition and antinociception. Biochem Pharmacol 1997;53:1451-7.
    • (1997) Biochem Pharmacol , vol.53 , pp. 1451-1457
    • Ouellet, D.M.1    Pollack, G.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.