Activation of the mitogen-activated protein kinase, Slt2p, at bud tips blocks a late stage of endoplasmic reticulum inheritance in Saccharomyces cerevisiae

Molecular Biology of the Cell

Volumn 21, Issue 10, 2010, Pages 1772-1782

  Li, Xia ^b   Du, Yunrui ^a,b,c   Siegel, Steven ^a,b   Ferro Novick, Susan ^b   Novick, Peter ^b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Transtec Global Group   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; MSS4 PROTEIN; PROTEIN KINASE; PROTEIN PATCHED 1; SLT2 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BUD; CELL CYCLE; CELL NUCLEUS; CELL WALL; CONTROLLED STUDY; DAUGHTER CELL; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; ENZYME INACTIVATION; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SACCHAROMYCES CEREVISIAE;

CELL WALL; ENDOPLASMIC RETICULUM; MITOGEN-ACTIVATED PROTEIN KINASES; MUTATION; PHOSPHOPROTEIN PHOSPHATASES; PHOSPHORYLATION; SACCHAROMYCES CEREVISIAE;

SACCHAROMYCES CEREVISIAE;

EID: 77952396452     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E09-06-0532     Document Type: Article

References (27)

1. Audhya, A., and Emr, S. D. (2002). Stt4 PI 4-kinase localizes to the plasma membrane and functions in the Pkc1-mediated MAP kinase cascade. Dev. Cell 2, 593-605. (Pubitemid 34538140)
2. Baetz, K., Moffat, J., Haynes, J., Chang, M., and Andrews, B. (2001). Transcriptional coregulation by the cell integrity mitogen-activated protein kinase Slt2 and the cell cycle regulator Swi4. Mol. Cell. Biol. 21, 6515-6528.
3. Du, Y., Ferro-Novick, S., and Novick, P. (2004). Dynamics and inheritance of the endoplasmic reticulum. J. Cell Sci. 117, 2871-2878.
4. Du, Y., Walker, L., Novick, P., and Ferro-Novick, S. (2006). Ptc1p regulates cortical ER inheritance via Slt2p. EMBO J. 25, 4413-4422. (Pubitemid 44498116)
5. Estrada, P., Kim, J., Coleman, J., Walker, L., Dunn, B., Takizawa, P., Novick, P., and Ferro-Novick, S. (2003). Myo4p and She3p are required for cortical ER inheritance in Saccharomyces cerevisiae. J. Cell Biol. 163, 1255-1266.
6. Fehrenbacher, K. L., Davis, D., Wu, M., Boldogh, I., and Pon, L. A. (2002). Endoplasmic reticulum dynamics, inheritance, and cytoskeletal interactions in budding yeast. Mol. Biol. Cell 13, 854-865.
7. Harrison, J. C., Bardes, E. S., Ohya, Y., and Lew, D. J. (2001). A role for the Pkc1p/Mpk1p kinase cascade in the morphogenesis checkpoint. Nat. Cell Biol. 3, 417-420.
8. Huang, K. N., and Symington, L. S. (1995). Suppressors of a Saccharomyces cerevisiae pkc1 mutation identify alleles of the phosphatase gene PTC1 and of a novel gene encoding a putative basic leucine zipper protein. Genetics 141, 1275-1285.
9. Jin, Y., Taylor Eves, P., Tang, F., and Weisman, L. S. (2009). PTC1 is required for vacuole inheritance and promotes the association of the myosin-V vacuole-specific receptor complex. Mol. Biol. Cell 20, 1312-1323.
10. Jung, U. S., and Levin, D. E. (1999). Genome-wide analysis of gene expression regulated by the yeast cell wall integrity signalling pathway. Mol. Microbiol. 34, 1049-1057.
11. Kamada, Y., Qadota, H., Python, C. P., Anraku, Y., Ohya, Y., and Levin, D. E. (1996). Activation of yeast protein kinase C by Rho1 GTPase. J. Biol. Chem. 271, 9193-9196.
12. La Cour, T., Gupta, R., Rapacki, K., Skriver, K., Poulsen, F. M., and Brunak, S. (2003). NESbase version 1.0, a database of nuclear export signals. Nuclear Acids Res. 31, 393-396. (Pubitemid 36150410)
13. Levin, D. E. (2005). Cell wall integrity signaling in Saccharomyces cerevisiae. Microbiol. Mol. Biol. Rev. 69, 262-291.
14. Madden, K., Sheu, Y. J., Baetz, K., Andrews, B., and Snyder, M. (1997). SBF cell cycle regulator as a target of the yeast PKC-MAP kinase pathway. Science 275, 1781-1784. (Pubitemid 27136713)
15. Manning, B. D., Padmanabha, R., and Snyder, M. (1997). The Rho-GEF Rom2p localizes to sites of polarized cell growth and participates in cytoskeletal functions in Saccharomyces cerevisiae. Mol. Biol. Cell 8, 1829-1844. (Pubitemid 27451105)
16. Martin, H., Flandez, M., Nombela, C., and Molina, M. (2005). Protein phosphatases in MAPK signalling: we keep learning from yeast. Mol. Microbiol. 58, 6-16.
17. Martin, H., Rodriguez-Pachon, J. M., Ruiz, C., Nombela, C., and Molina, M. (2000). Regulatory mechanisms for modulation of signaling through the cell integrity Slt2-mediated pathway in Saccharomyces cerevisiae. J. Biol. Chem. 275, 1511-1519. (Pubitemid 30051213)
18. Rajavel, M., Philip, B., Buehrer, B. M., Errede, B., and Levin, D. E. (1999). Mid2 is a putative sensor for cell integrity signaling in Saccharomyces cerevisiae. Mol. Cell. Biol. 19, 3969-3976.
19. Reinke, C. A., Kozik, P., and Glick, B. S. (2004). Golgi inheritance in small buds of Saccharomyces cerevisiae is linked to endoplasmic reticulum inheritance. Proc. Natl. Acad. Sci. USA 101, 18018-18023.
20. Roeder, A. D., Hermann, G. J., Keegan, B. R., Thatcher, S. A., and Shaw, J. M. (1998). Mitochondrial inheritance is delayed in Saccharomyces cerevisiae cells lacking the serine/threonine phosphatase PTC1. Mol. Biol. Cell 9, 917-930.
21. Sheu, Y. J., Santos, B., Fortin, N., Costigan, C., and Snyder, M. (1998). Spa2p interacts with cell polarity proteins and signaling components involved in yeast cell morphogenesis. Mol. Cell. Biol. 18, 4053-4069.
22. van Drogen, F., and Peter, M. (2002). Spa2p functions as a scaffold-like protein to recruit the Mpk1p MAP kinase module to sites of polarized growth. Curr. Biol. 12, 1698-1703.
23. Voeltz, G. K., Rolls, M. M., and Rapoport, T. A. (2002). Structural organization of the endoplasmic reticulum. EMBO Rep. 3, 944-950.
24. Watanabe, Y., Irie, K., and Matsumoto, K. (1995). Yeast RLM1 encodes a serum response factor-like protein that may function downstream of the Mpk1 (Slt2) mitogen-activated protein kinase pathway. Mol. Cell. Biol. 15, 5740-5749.
25. Wiederkehr, A., Du, Y., Pypaert, M., Ferro-Novick, S., and Novick, P. (2003). Sec3p is needed for the spatial regulation of secretion and for the inheritance of the cortical endoplasmic reticulum. Mol. Biol. Cell 14, 4770-4782.
26. Yoshida, S., Ohya, Y., Goebl, M., Nakano, A., and Anraku, Y. (1994). A novel gene, STT4, encodes a phosphatidylinositol 4-kinase in the PKC1 protein kinase pathway of Saccharomyces cerevisiae. J. Biol. Chem. 269, 1166-1172.
27. Zarzov, P., Mazzoni, C., and Mann, C. (1996). The SLT2(MPK1) MAP kinase is activated during periods of polarized cell growth in yeast. EMBO J. 15, 83-91. (Pubitemid 26020391)