Emotional indifference in Alzheimer's disease

Journal of Neuropsychiatry and Clinical Neurosciences

Volumn 22, Issue 2, 2010, Pages 236-242

  Drago, Valeria ^a,b,c   Foster, P S ^a,d   Chanei, L ^a   Rembisz, J ^a   Meador, K ^a   Finney, G ^a   Heilman, K M ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF BOLOGNA   (Italy)

^c OASI RESEARCH INSTITUTE IRCCS   (Italy)

^d Middle Tennessee State University   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; ARTICLE; CLINICAL ARTICLE; COMPREHENSION; CONTROLLED STUDY; DECISION MAKING; EMOTION; FEMALE; HUMAN; MALE; MINI MENTAL STATE EXAMINATION; PRIORITY JOURNAL;

EID: 77952395113     PISSN: 08950172     EISSN: None     Source Type: Journal    
DOI: 10.1176/jnp.2010.22.2.236     Document Type: Article

References (30)

1. McKhann G, Drachman D, Folstein M, et al: Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA work group under the auspices of the Department of Health and Human Service Task Force on Alzheimer's Disease. Neurology 1984; 34:939-944 (Pubitemid 14076461)
2. Oppenheim G: The earliest sign of Alzheimer's disease. J Am Geriatr Soc 1994; 37:511-514
3. Patterson MB, Mack JL, Mackell JA, et al: A longitudinal study of behavioral pathology across five levels of dementia severity in Alzheimer's disease: the Cerad Behavior Rating Scale for Dementia. The Alzheimer's Disease Cooperative Study. Alzheimer Dis Assoc Disord 1997; 11(suppl 2):S40-S44
4. Heilman KM, Valenstein E: Emotional disorders associated with neurological disease, in Clinical Neuropsychology. Edited by Heilman KM, Valenstein E. New York, Oxford University Press, 2003, pp 447-478
5. Levy ML, Cummings LA, Fairbanks D, et al: Apathy is not depression. J Neuropsychiatry Clin Neurosci 1998; 10:314-319
6. Marshall GA, Monserratt L, Harwood D, et al: Positron emission tomography metabolic correlates of apathy in Alzheimer disease. Arch Neurol 2007; 64:1015-1020 (Pubitemid 47048003)
7. Marin RS: Apathy: a neuropsychiatric syndrome. J Neuropsychiatry Clin Neurosci 1991; 3:243-254
8. Cummings JL: The Neuropsychiatric Inventory: assessing psychopathology in dementia patients. Neurology 1997; 48: S10-16
9. Testa JA, Beatty WW, Gleason AC, et al: Impaired affective prosody in AD: relationship to aphasic deficits and emotional behaviors. Neurology 2001; 57:1474-1481 (Pubitemid 32995731)
10. Brosgole L, Kuruez J, Plahovinsak TJ, et al: On the mechanism underlying facial-affective agnosia in senile demented patients. Int J Neurosci 1981; 15:207-215 (Pubitemid 12251850)
11. Allender J, Kaszniak AW: Processing of emotional cues in patients with dementia of the Alzheimer's type. Int J Neurosci 1989; 46:147-155
12. Lang JP, Bradley MM, Cuthbert BN: The International Affective Picture System [photographic slides]. Gainesville, Fla: The Center for Research in Psychophysiology, University of Florida, 2001
13. Grühn D, Scheibe S: Age-related differences in valence and arousal ratings of pictures from the International Affective Picture System (IAPS): do ratings become more extreme with age? Behav Res Methods 2008; 40:512-521
14. Dunn BD, Dalgleish T, Lawrence AD, et al: Categorical and dimensional reports of experienced affect to emotion inducing pictures in depression. J Abnorm Psychol 2004; 113:654-660 (Pubitemid 39431119)
15. Sloan DM, Strauss ME, Quirk SW, et al: Subjective and expressive emotional responses in depression. J Affect Disord 1997; 46:135-141
16. Sloan DM, Strauss ME, Wisner KL: Diminished response to pleasant stimuli by depressed women. J Abnorm Psychol 2001; 110:488-493
17. Blonder LX, Bowers D, Heilman KM: The role of the right hemisphere in emotional communication. Brain 1991; 114:1115-1127
18. Bradley MM, Sabatinelli D, Lang PJ, et al: Activation of the visual cortex in motivated attention. Behav Neurosci 2003; 117:369-380 (Pubitemid 36384255)
19. Albert MS, Cohen C, Koff E: Perception of affect in patients with dementia of the Alzheimer type. Arch Neurol 1991; 48:791-795
20. Lehtovirta M, Laakso MP, Frisoni GB, et al: How does the apolipoprotein E genotype modulate the brain in aging and in Alzheimer's disease? A review of neuroimaging studies. Neurobiol Aging 2000; 21:293-300 (Pubitemid 30387088)
21. Reiman EM, Caselli RJ, Chen K, et al: Declining brain activity in cognitively normal apolipoprotein E epsilon 4 heterozygotes: a foundation for using positron emission tomography to efficiently test treatments to prevent Alzheimer's disease. Proc Natl Acad Sci USA 2001; 98:3334-3339 (Pubitemid 32220846)
22. Stark R, Schienle A, Walter B, et al: Hemodynamic responses to fear and disgust-inducing pictures: an fMRI study. Int J Psychophysiol 2003; 50:225-234 (Pubitemid 37329731)
23. Stark R, Schienle A, Walter B, et al: Hemodinamic effects of negative emotional pictures: a test-retest analysis. Neuropsychobiology 2004; 50:108-118 (Pubitemid 38721177)
24. Hamann S, Monarch ES, Goldstein FC: Impaired fear conditioning in Alzheimer's disease. Neuropsychologia 2002; 40:1187-1195 (Pubitemid 34249830)
25. Britton JC, Taylor SF, Sudheimer KD, et al: Facial expression and complex IAPS pictures: common and differential networks. Neuroimage 2006; 31:906-919
26. LeDoux JE: Emotion circuits in the brain. Annu Rev Neurosci 2000; 23:155-184
27. Marshall GA, Fairbanks LA, Tekin S, et al: Neuropathologic correlates of apathy in Alzheimer's disease. Dement Geriatr Cogn Disord 2006; 21:144-147 (Pubitemid 43201323)
28. Tales A, Snowden RJ, Brown M, et al: Alerting and orienting in Alzheimer's disease. Neuropsychology 2006; 20:752-756
29. Festa EK, Ott BR, Heindel WC: Considering phasing alerting in Alzheimer's disease: comment on Tales et al. (2006). Neuropsychology 2006; 20:757-760
30. Van Stegeren AH, Goekoop R, Everaerd W, et al: Noradrenaline mediates amygdale activation in men and women during encoding of emotional material. Neuroimage 2005; 24:898-909 (Pubitemid 40094571)