Effects of astragalosides and Panax notoginseng saponins combination on oxidative stress of cerebral ischemic reperfusion injury in mice

Journal of Chinese Integrative Medicine

Volumn 8, Issue 5, 2010, Pages 448-452

  Tan, Hua ^a   Huang, Xiao Ping ^a   Deng, Chang Qing ^a  

^a HUNAN UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Astragalosides; C57BL 6 mice; Cerebral ischemia; Oxidative stress; Panax notoginseng saponins; Reperfusion injury

Indexed keywords

ASTRAGALOSIDE; GLUTATHIONE; MALONALDEHYDE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NORPHENAZONE; PANAX NOTOGINSENG EXTRACT; PLANT MEDICINAL PRODUCT; SAPONIN; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN HOMOGENATE; BRAIN ISCHEMIA; CAROTID ARTERY LIGATION; COMMON CAROTID ARTERY; CONTROLLED STUDY; DRUG EFFECT; DRUG MEGADOSE; DRUG POTENTIATION; LIPID PEROXIDATION; LOW DRUG DOSE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PANAX NOTOGINSENG; REPERFUSION INJURY; ANIMAL; BRAIN; C57BL MOUSE; CHEMISTRY; MALE; METABOLISM;

ANIMALS; BRAIN; BRAIN ISCHEMIA; MALE; MICE; MICE, INBRED C57BL; OXIDATIVE STRESS; PANAX NOTOGINSENG; REPERFUSION INJURY; SAPONINS;

EID: 77952382686     PISSN: 16721977     EISSN: None     Source Type: Journal    
DOI: 10.3736/jcim20100508     Document Type: Article

References (10)

1. Li H, Chen G, Deng CQ. Effects of plasma containing Buyang Huanwu Decoction and its effective components and total Panax notoginseng saponins on vascular smooth muscle cell proliferation induced by platelet-derived growth factor. J Chin Integr Med. 2009; 7 (11): 1078-1085. Chinese with abstract in English. 2009; 7(11): 1078-1085.
2. Yang G, Kitagawa K, Matsushita K, Mabuchi T, Yagita Y, Yanagihara T, Matsumoto M. C57BL/6 strain is most susceptible to cerebral ischemia following bilateral common carotid occlusion among seven mouse strains: selective neuronal death in the murine transient forebrain ischemia. Brain Res. 1997; 752(1-2): 209-218.
3. Wellons JC 3rd, Sheng H, Laskowitz DT, Burkhard Mackensen G, Pearlstein RD, Warner DS. A comparison of strain-related susceptibility in two murine recovery models of global cerebral ischemia. Brain Res. 2000; 868(1): 14-21.
4. Rodrigo J, Fernandez AP, Serrano J, Peinado MA, Martinez A. The role of free radicals in cerebral hypoxia and ischemia. Free Radic Biol Med. 2005; 39(1): 26-50.
5. Chen X. Cardiovascular pharmacology. Beijing: People's Medical Publishing House. 2003: 237-242. Chinese. 2003: 237-242.
6. Liu PK, Grossman RG, Hsu CY, Robertson CS. Ischemic injury and faulty gene transcripts in the brain. Trends Neurosci. 2001; 24(10): 581-588.
7. Ikeda Y, Long DM. The molecular basis of brain injury and brain edema: the role of oxygen free radicals. Neurosurgery. 1990; 27(1): 1-11.
8. Nishi T, Maier CM, Hayashi T, Saito A, Chan PH. Superoxide dismutase 1 overexpression reduces MCP-1 and MIP-1 alpha expression after transient focal cerebral ischemia. J Cereb Blood Flow Metab. 2005; 25(10): 1312-1324.
9. Tokime T, Nozaki K, Sugino T, Kikuchi H, Hashimoto N, Ueda K. Enhanced poly (ADP-ribosyl) ation after focal ischemia in rat brain. J Cereb Blood Flow Metab. 1998; 18(9): 991-997.
10. Chen CM, Yang WZ. The role of nitric oxide and nitric oxide synthase in cerebral ischemic reperfusion injury. Yi Xue Zong Shu. 2005; 11(12): 1057-1059. Chinese. 2005; 11(12): 1057-1059.