The effect of simvastatin on the proteome of detergent-resistant membrane domains: Decreases of specific proteins previously related to cytoskeleton regulation, calcium homeostasis and cell fate

Proteomics

Volumn 10, Issue 10, 2010, Pages 1954-1965

  Ponce, Jovita ^a   Brea, David ^b   Carrascal, Montserrat ^c   Guirao, Verónica ^a   DeGregorio Rocasolano, Nuria ^a   Sobrino, Tomás ^b   Castillo, José ^b   Dávalos, Antonio ^a   Gasull, Teresa ^a  

^a FUNDACIÓ INSTITUT D INVESTIGACIÓ EN CIÈNCIES DE LA SALUT GERMANS TRIAS I PUJOL   (Spain)

^b Instituto de Salud Carlos III   (Spain)

^c CSIC   (Spain)

Author keywords

Cell biology; Detergent resistant membranes; Excitotoxicity; Lipid rafts; Neuroprotection; Statins

Indexed keywords

CALRETININ; ENOLASE; F ACTIN; F ACTIN CAPPING PROTEIN ALPHA1; F ACTIN CAPPING PROTEIN ALPHA2; HEAT SHOCK COGNATE PROTEIN 71; HEAT SHOCK PROTEIN; KHELLIN; MALATE DEHYDROGENASE; MEMBRANE PROTEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N MYC DOWNREGULATED GENE 1; PROHIBITIN; PROHIBITIN 2; RAB PROTEIN; SIMVASTATIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; CALCIUM HOMEOSTASIS; CELL FATE; CONTROLLED STUDY; DRUG EFFECT; EMBRYO; FETUS; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN LOCALIZATION; RAT;

ANIMALS; CALCIUM; CELL MEMBRANE; CELLS, CULTURED; CYTOSKELETON; HOMEOSTASIS; PROTEOME; RATS; RATS, SPRAGUE-DAWLEY; SIMVASTATIN;

EID: 77952382228     PISSN: 16159853     EISSN: 16159861     Source Type: Journal    
DOI: 10.1002/pmic.200900055     Document Type: Article

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