Lawsonia intracellularis infection in the horse -a problem in Germany? First safety data on a vaccine in foals;Lawsonia-intracellularis-Erkrankungen beim Pferd -auch in Deutschland ein Problem? Erste Verträglichkeitsdaten eines Impfstoffes bei Fohlen

Praktische Tierarzt

Volumn 91, Issue 4, 2010, Pages 316-325

  Westhoff, Doris ^a   Kissel, Carola ^b   Schuon, Carolin ^b  

^a Boehringer Ingelheim Vetmedica GmbH ^*  (United States)

^b BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

Equine proliferative enteropathy; Foal vaccination; Lawsonia intracellulars

Indexed keywords

DESULFOVIBRIONACEAE; EQUIDAE; LAWSONIA (BACTERIA); LAWSONIA INTRACELLULARIS; SUIDAE; SUS;

EID: 77952375085     PISSN: 0032681X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (45)

1. Atherton O, McKenzie HC (2006): Alternative Antimicrobial Agents in the Treatment of Proliferative Enteropathy in Horses. J Equine Vet Sci 26: 535-541.
2. Beckler D, Amonsin A, Kapur V, Gebhart C (2004): Multiple-Locus variable number tandem repeat analysis for the differentiation of Lawsonia intracellularis isolates. Proceedings of the Annual Meeting of the American Association of Swine Veterinarians, 41-43.
3. Bihr TP (2003): Protein-losing enteropathy caused by Lawsonia intracellularis in a weaning foal. Can Vet J 44: 65-66.
4. Boesen HT, Jensen TK, Møller K, Nielsen LH, Jungersen G (2005): Evaluation of a novel enzyme-linked immunosorbant assay for serological diagnosis of porcine. Vet Microbiol 109: 105-112.
5. Brees DJ, Sondhoff AH, Kluge JP, Andreasen CB, Brown CM (1999): Lawsonia intracellulars - like organism infection in a miniature foal. J Am Vet Med Assoc 215: 511-514.
6. Butler CM, Nijhof A, Klarenbeek S, Meeus P, v. Niieuwstadt RA, Sloet van Oldruittenborgh-Oosterbaan MM (2006): Lawsonia intracellulars infection in friesian foals. Scientific Proceedings Voorjaarsdagen, Amsterdam 3, 73.
7. Collins A, Love R, Pozo J, Love RJ (2000): Studies on an ex vivo survival of Lawsonia intracellularis. Swine Health Prod 8: 211-215.
8. Cooper DM, Swanson DL, Gebhart CJ (1996): Diagnosis of proliferative enteritis in frozen and formalin-fixed, paraffin-embedded tissues from a hamster, horse, deer and ostrich using a Lawsonia intracellulars specific multiplex PCR assay. Vet Microbiol 54: 47-62.
9. Dauvillier J, Picandet V, Harel J, Gottschalk M, Desrosiers R, Jean D, Lavoie JP (2006): Diagnostic and epidemiological features of Lawsonia intracellulars enteropathy in 2 foals. Can Vet J 47: 689-691.
10. Deprez P, Chiers K, Gebhart CJ, Ducatelle R, Lefère L, Vanschandevijl K, van Loon G (2005): Lawsonia intracellulars infection in a 12-month-old colt in Belgium. Vet Rec 157: 774-776.
11. Dezorova-Tomanova K, Smola J, Trcka I, Laka J, Pavlik I (2006): Detection of Lawsonia intracellulars in Wild Boar and Fallow Deer Bred in One Game Enclosure in the Czech Republic. J Vet Med B56: 42-44.
12. Duhamel GE, Wheeldon EB (1982): Intestinal adenomatosis in a foal. Vet Pathol 19: 447-450.
13. Epstein K, Short D, Parente V, South wood L (2008): Gastrointestinal ultrasonsgraphy in normal adult ponies. Vet Radiol Ultrasound 49 (3): 282-286. (Pubitemid 351629898)
14. Feary DJ, Gebhart CJ, Pusterla N (2006): Lawsonia intracellularis proliferative enteropathy in a foal. Schweiz Arch Tierheilkd 149: 129-133.
15. Frank N, Fishman CE, Gebhart CJ, Levy M (1998): Lawsonia intracellularis proliferative enteropathy in a weanling foal. Equine Vet J 30: 549-552.
16. th meeting of the ACVIM, Seattle WA, 168-170.
17. Frazer ML (2008): Lawsonia intracellularis Infection: 2005-2007. J Vet Intern Med 22: 1243-1248.
18. Guedes RMC, Gebhart CJ, Deen J, Winkelmann NL (2002): Validation of an immunoperoxidase monolayer assay as a serologic test for porcine proliferative enteropathy. J Vet Diagn Invest 14: 528-530. (Pubitemid 135747524)
19. Herbst W, Hertrampf B, Schmitt T, Baljer G (2003): Diagnostic of Lawsonia intracellulars in pigs with and without diarrhoea and other animal species using polymerase chain reaction (PCR). Dtsch Tierärztl Wschr 110: 361-364.
20. Horín P, Smola J, Matiasovic J, Vyskocil M, Lukeszová L, Tomanová K, Králík P, Glasnák V, Schröffelová D, Knoll A, Sedlinská M, Krenková L, Jahn P (2004): Polymorphismus in equine immune response genes and their associations with infections Mamm Genome 15, 843-850.
21. Jasni S, McOrist S, Lawson GHK (1994): Experimentally induced proliferation enteritis in hamsters: an ultrastructural study. Res Vet Sci 56: 186-192.
22. Johnston RH, Kamstra LD, Kohler PH (1970): Mares' milk composition as related to "foal heat" scours. J Animal Sci 31: 549-553.
23. Knittel JP, Jordan D, Schwartz K, Janke B, Roof M, McOrist S, Harris D (1998): Evaluation of ante mortem polymerase chain reaction and serological methods for the detection of Lawsonia intracellulars. Am J Vet Res 526: 722-726.
24. th International Pig Veterinary Society Congress, Hamburg, Germany, 307.
25. Kroll JJ, Roof MB, Elbers K, Walter D, Utley P (2004): Evaluation of an avirulent live vaccine of Lawsonia intracellularis. J Vet Res 65: 559-565.
26. Kroll JJ, Roof MB, Hoffman LJ, Dickson JS, Harris DLH (2005a): Proliferative enteropathy: a global enteric disease of pigs caused by Lawsonia intracellulars. Anim Health Res Rev 6: 173-197.
27. Kroll JJ, Eichmeyer MA, Schaeffer ML, McOrist S, Harris DL (2005b): Lipopolysaccaride-based enzyme-linked immunosorbant assay for experimental use in detection of antibodies to Lawsonia intracellulars in pigs. Lab Immunol 12: 693-699.
28. Lavoie JP, Drolet R, Parsons D, Leguillette R, Sauvageau R, Shapiro J, Houle L, Halle G, Gebhart CJ (2000): Equine prolife-rative enteropathy: a cause of weight loss, colic, diarrhoea and hypoproteinemia in foals on three breeding farms in Canada. Equine Vet J 32: 418-425.
29. Lavoie JP, Drolet R (2007): Lawsonia intracellulars. In: Sellon DS, Long MT (Hrsg.), Equine Infectious Diseases. Saunders Elsevier, St. Louis, 313-316.
30. Lawson GHK, Gebhart CJ (2000): Proliferative Enteropathy. J Comp Path 122: 77-100.
31. Masri MD, Merritt AM, Gronwall R, Burrows CF (1986): Faecal composition in foal heat diarrhoea. Equine Vet J 18: 301-306.
32. McClintock SA, Collins AM (2004): Lawsonia intracellulars proliferative enteropathy in a weanling foal in Australia. Austr Vet J 82: 750-752.
33. McOrist S, Barcellos D, Wilson R (2003): Global patterns of porcine Proliferative Enteropathy. Pig J 51: 26-35.
34. McGurrin MKJ, Vengust M, Arroyo LG, Baird JD (2007): An outbreak of Lawsonia intracellulars infection in a standardbred herd in Ontario. Can Vet J 48: 927-930.
35. Pusterla N, Hilton H, Wattanaphansak S, Collier JR, Mapes SM, Stenbaum RM, Gebhart C (2009a): Evaluation of the humoral immune response and fecal shedding in weanling foals following oral and intra-rectal administration of an avirulent live vaccine of Lawsonia intracellulars. Vet J 180, 279-289.
36. Pusterla N, Jackson R, Wilson R, Collie J, Mapes S, Gebhart CL (2009b): Temporal detection of Lawsonia intracellulars using serology and real-time PCR in Thoroughbred horses residing on a farm endemic for equine proliferative enteropathy. Vet Microbiol 136 (1-2): 173-176.
37. Rowland AC, Lawson GHK(1992): Porcine proliferative enteropathies. In: Leman AD., Straw BE, Mengeling WL (Hrsg.), Diseases of Swine. Iowa State University Press, Ames, 560-569.
38. Sampieri FKW Hichcliff, Toribio RE (2006): Tetracycline therapy of Lawsonia intracellulars enteropathy in foals. Equine Vet J 38: 89-92.
39. Schumacher J, Schumacher J, Rolsma M, Brock KV, Gebhart CJ (2000): Surgical and Medical Treatment of an Arabian Filly with Proliferative Enteropathy caused by Lawsonia intracellularis. J Vet Intern Med 14: 630-632.
40. Smith DGE, Lawson GHK (2001): Lawsonia intracellularis: getting inside the pathogenesis of proliferative enteropathy. Vet Microbiol 82: 331-345.
41. Stämpfli H, Olimpo EO (2006): Chronic Diarrhea and Weight Loss in three Horses. Vet Clin Equine 22: e27-e35.
42. Walton MG (2007): Lawsonia intracellularis outbreaks in the Western Cape. Equine Health Update 9: 21-23.
43. Williams NM, Harrsion LR, Gebhart CJ (1996): Proliferative enteropathy in a foal caused by Lawsonia intracellularis like bacterium. J Vet Diagn Invest 8: 254-256.
44. Wong DM, Alcott CJ, Sponseller BA, Young JL, Sonseller BT (2009): Impaired Intestinal Absorption of Glucose in 4 Foals with Lawsonia intracellularis Infection. J Vet Intern Med 23, 940-944.
45. Würsch K, Huessey D, Koch C, Oevermann A (2006): Lawsonia intracellularis Proliferative Enteropathy in a Filly. J Vet Med 53: 17-21.