Vagus nerve stimulation regulates hemostasis in swine

Shock

Volumn 33, Issue 6, 2010, Pages 608-613

  Czura, Christopher J ^a,b   Schultz, Arthur ^c   Kaipel, Martin ^c   Khadem, Anna ^c   Huston, Jared M ^a   Pavlov, Valentin A ^a   Redl, Heinz ^c   Tracey, Kevin J ^a,b  

^a FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

^b STONY BROOK UNIVERSITY   (United States)

^c LUDWIG BOLTZMANN INSTITUTE FOR EXPERIMENTAL AND CLINICAL TRAUMATOLOGY   (Austria)

Author keywords

7 nAChR; Hemorrhage; Hemostasis; Inflammatory reflex; Thrombin antithrombin complex

Indexed keywords

ANTITHROMBIN III; BLOOD CLOTTING FACTOR; THROMBIN;

ANIMAL EXPERIMENT; ARTICLE; BLEEDING; BLEEDING TIME; BLOOD CLOTTING; BLOOD PRESSURE; CONTROLLED STUDY; EAR SURGERY; ELECTROSTIMULATION; FEMALE; HEART RATE; HEMOSTASIS; MALE; NONHUMAN; SOFT TISSUE INJURY; SWINE; VAGUS NERVE STIMULATION;

ANIMALS; BLOOD COAGULATION; BLOOD PRESSURE; EAR; ELECTRIC STIMULATION; SWINE; VAGUS NERVE;

EID: 77952370532     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/SHK.0b013e3181cc0183     Document Type: Article

References (25)

1. Tracey KJ: The inflammatory reflex. Nature 420(6917):853-859, 2002.
2. Czura CJ, Tracey KJ: Autonomic neural regulation of immunity. J Intern Med 257(2):156-166, 2005.
3. Borovikova LV, Ivanova S, Zhang M, Yang H, Botchkina GI, Watkins LR, Wang H, Abumrad N, Eaton JW, Tracey KJ: Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin. Nature 405(6785): 458-462, 2000.
4. Wang H, Yu M, Ochani M, Amella CA, Tanovic M, Susarla S, Li JH, Wang H, Yang H, Ulloa L, et al.: Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation. Nature 421(6921):384-388, 2003.
5. Lawson JH, Kalafatis M, Stram S, Mann KG: A model for the tissue factor pathway to thrombin. I. An empirical study. J Biol Chem 269(37): 23357-23366, 1994.
6. Rand MD, Lock JB, van't Veer C, Gaffney DP, Mann KG: Blood clotting in minimally altered whole blood. Blood 88(9):3432-3445, 1996.
7. Butenas S, van 't Veer C, Mann KG: Evaluation of the initiation phase of blood coagulation using ultrasensitive assays for serine proteases. J Biol Chem 272(34):21527-21533, 1997.
8. Brummel KE, Butenas S, Mann KG: An integrated study of fibrinogen during blood coagulation. J Biol Chem 274(32):22862-22870, 1999.
9. Cawthern KM, van 't Veer C, Lock JB, DiLorenzo ME, Branda RF, Mann KG: Blood coagulation in hemophilia A and hemophilia C. Blood 91(12): 4581-4592, 1998.
10. van 't Veer C, Mann KG: Regulation of tissue factor initiated thrombin generation by the stoichiometric inhibitors tissue factor pathway inhibitor, antithrombin-III, and heparin cofactor-II. J Biol Chem 272(7):4367-4377, 1997.
11. Olson ST, Björk I, Shore JD: Kinetic characterization of heparin-catalyzed and uncatalyzed inhibition of blood coagulation proteinases by antithrombin. Methods Enzymol 222:525-559, 1993.
12. Girard TJ, Warren LA, Novotny WF, Likert KM, Brown SG, Miletich JP, Broze GJ Jr: Functional significance of the Kunitz-type inhibitory domains of lipoprotein-associated coagulation inhibitor. Nature 338(6215):518-520, 1989.
13. Rapaport SI: The extrinsic pathway inhibitor: a regulator of tissue factorY dependent blood coagulation. Thromb Haemost 66(1):6-15, 1991.
14. Broze GJ Jr, Warren LA, Novotny WF, Higuchi DA, Girard JJ, Miletich JP: The lipoprotein-associated coagulation inhibitor that inhibits the factor VII-tissue factor complex also inhibits factor Xa: insight into its possible mechanism of action. Blood 71(2):335-343, 1988.
15. Walker FJ, Sexton PW, Esmon CT: The inhibition of blood coagulation by activated Protein C through the selective inactivation of activated factor V. Biochim Biophys Acta 571(2):333-342, 1979.
16. Suzuki K, Stenflo J, Dahlbäck B, Teodorsson B: Inactivation of human coagulation factor V by activated protein C. J Biol Chem 258(3):1914-1920, 1983.
17. Hockin MF, Kalafatis M, Shatos M, Mann KG: Protein C activation and factor Va inactivation on human umbilical vein endothelial cells. Arterioscler Thromb Vasc Biol 17(11):2765-2775, 1997.
18. Eaton D, Rodriguez H, Vehar GA: Proteolytic processing of human factor VIII. Correlation of specific cleavages by thrombin, factor Xa, and activated protein C with activation and inactivation of factor VIII coagulant activity. Biochemistry 25(2):505-512, 1986.
19. Esmon CT: The regulation of natural anticoagulant pathways. Science 235(4794):1348-1352, 1987.
20. Esmon CT: Thrombomodulin as a model of molecular mechanisms that modulate protease specificity and function at the vessel surface. FASEB J 9(10):946-955, 1995.
21. Collen D, Schetz J, de Cock F, Holmer E, Verstraete M: Metabolism of antithrombin III (heparin cofactor) in man: effects of venous thrombosis and of heparin administration. Eur J Clin Invest 7(1):27-35, 1977.
22. Persson E, Bak H, Olsen OH: Substitution of valine for leucine 305 in factor VIIa increases the intrinsic enzymatic activity. J Biol Chem 276(31): 29195-29199, 2001.
23. Tracey KJ: Reflex control of immunity. Nat Rev Immunol 9(6):418-428, 2009.
24. Daban C, Martinez-Aran A, Cruz N, Vieta E: Safety and efficacy of vagus nerve stimulation in treatment-resistant depression. A systematic review. J Affect Disord 110(1-2):1-15, 2008.
25. Ramani R: Vagus nerve stimulation therapy for seizures. J Neurosurg Anesthesiol 20(1):29-35, 2008.