Hepatic adiponectin receptor R2 expression is up-regulated in normal adult male mice by chronic exogenous growth hormone levels

Molecular Medicine Reports

Volumn 3, Issue 3, 2010, Pages 525-530

  Ying, Qin ^a   Tian, Y A Ping ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Adiponectin; Adiponectin receptors R1 and R2; Growth hormone

Indexed keywords

ADIPONECTIN; ADIPONECTIN RECEPTOR 1; ADIPONECTIN RECEPTOR 2; GLUCOSE; GROWTH HORMONE; INSULIN; MESSENGER RNA; PARVOVIRUS VECTOR; PLACEBO; RECOMBINANT GROWTH HORMONE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CYTOMEGALOVIRUS; DRUG DELIVERY SYSTEM; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; GROWTH HORMONE BLOOD LEVEL; HOMEOSTASIS; INJECTION; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIVER; MALE; MOLECULAR WEIGHT; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR UPREGULATION; RISK FACTOR; SINGLE DRUG DOSE; SKELETAL MUSCLE; VIRUS PARTICLE; WESTERN BLOTTING;

MUS;

EID: 77952342836     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr-00000292     Document Type: Article

References (38)

1. Berg AH, Combs TP and Scherer PE: ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism. Trends Endocrinol Metab 13: 84-89, 2002.
2. Berg AH, Combs TP, DU X, Brownlee M and Scherer PE: The adipocyte-secreted protein Acrp30 enhances hepatic insulin action. Nat Med 7: 947-953, 2001. (Pubitemid 32756433)
3. Arita Y, Kihara S, Ouchi N, et al: Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun 257: 79-83, 1999.
4. Yamamoto Y, Hirose H, Saito I, et al: Correlation of the adipocyte derived protein adiponectin with insulin resistance index and serum high-density lipoprotein cholesterol, independent of body mass index, in the Japanese population. Clin Sci 103: 137-142, 2002.
5. Yildiz Bo, Suchard Ma, Wong ML, McCann SM and Licinio J: Alterations in the dynamics of circulating ghrelin, adiponectin, and leptin in human obesity. Proc Natl Acad Sci USA 101: 10434-10439, 2004.
6. Trujillo ME and Scherer PE: Adiponectin-journey from an adipocyte secretory protein to biomarker of the metabolic syndrome. J Intern Med 257: 167-175, 2005.
7. Yamamoto N, Oshima T, Yoshihara K, et al: Reduced expression of the AdipoR1 gene is correlated with venous invasion in colorectal cancer. Mol Med rep 2: 555-559, 2009.
8. ceddia RB, Somwar R, Maida A, Fang X, Bikopoulos G and Sweeney G: Globular adiponectin increases GLUT4 translocation and glucose uptake but reduces glycogen synthesis in rat skeletal muscle cells. Diabetologia 48: 132-139, 2005.
9. Fang X, Palanivel R, Zhou X, et al: Hyperglycemia- and hyperinsulinemia-induced alteration of adiponectin receptor expression and adiponectin effects in L6 myoblasts. J Mol Endocrinol 35: 465-476, 2005.
10. Tomas E, Tsao TS, Saha aK, et al: Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP activated protein kinase activation. Proc Natl Acad Sci USA 99: 16309-16313, 2002.
11. Fruebis J, Tsao TS, Javorschi S, et al: Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice. Proc Natl Acad Sci USA 98: 2005-2010, 2001.
12. Onay-Besikci A, Altarejos JY and Lopaschuk GD: gAd-globular head domain of adiponectin increases fatty acid oxidation in newborn rabbit hearts. J Biol chem 279: 44320-44326, 2004.
13. Wu X, Motoshima H, Mahadev K, Stalker TJ, Scalia R and Goldstein BJ: Involvement of AMP-activated protein kinase in glucose uptake stimulated by the globular domain of adiponectin in primary rat adipocytes. Diabetes 52: 1355-1363, 2003.
14. Palanivel R, Fang X, Park M, et al: Globular and full-length forms of adiponectin mediate specific changes in glucose and fatty acid uptake and metabolism in cardiomyocytes. Cardiovasc Res 75: 148-157, 2007. (Pubitemid 46873521)
15. Waki H, Yamauchi T, Kamon J, Ito Y, Uchida S and Kita S: Impaired multimerization of human adiponectin mutants associated with diabetes. Molecular structure and multimer formation of adiponectin. J Biol Chem 278: 40352-40363, 2003.
16. Wang Y, lam KS, Xu JY, Cooper GJ and Xu A: Adiponectin inhibits cell proliferation by interacting with several growth factors in an oligomerization dependent manner. J Biol Chem 280: 18341-18347, 2005.
17. Yamauchi T, Kamon J, Ito Y, et al: Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature 423: 762-769, 2003.
18. Kadowaki T and Yamauchi T: Adiponectin and adiponectin receptors. Endocr Rev 26: 439-451, 2005.
19. Kadowaki T, Yamauchi T, Kubota N, Hara K, Ueki K and Tobe K: Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome. J Clin Invest 116: 1784-1792, 2006. (Pubitemid 44033298)
20. Fasshauer M, Klein J, Kralisch S, Klier M, Lössner U, Blüher M and Paschke R: Growth hormone is a positive regulator of adiponectin receptor 2 in 3T3-L1 adipocytes. FEBS lett 558: 27-32, 2004.
21. Xu A, Wong LC, Wang Y, Xu JY, Cooper GJ and Lam KS: Chronic treatment with growth hormone stimulates adiponectin gene expression in 3T3-L1 adipocytes. FEBS Lett 572: 129-134, 2004. (Pubitemid 39092524)
22. Nilsson L, Binart Bohlooly-YM, et al: Prolactin and growth hormone regulate adiponectin secretion and receptor expression in adipose tissue. Biochem Biophys Res Commun 331: 1120-1126, 2005.
23. Qin Y and Tian YP: Microarray gene analysis of peripheral whole blood in normal adult male rats after chronic GH gene therapy. Cell Mol Biol Lett (In press).
24. Yan H, Guo YH, Zhang P, et al: Superior neovascularization and muscle regeneration in ischemic skeletal muscles following VEGF gene transfer by rAAV1 pseudotyped vectors. Biochem Biophys Res Commun 336: 278-287, 2005.
25. Snyder R, Xiao X and Samulski RJ: Production of recombinant adenoassociated viral vectors. In: Current Protocols in Human Genetics. Smith D (ed). Wiley, New York, pp12.1.1-12.2.23, 1996.
26. Kusano K, Tsutsumi Y, Dean J, et al: Long-term stable expression of human growth hormone by rAAV promotes myocardial protection post-myocardial infarction. J Mol Cell Cardiol 42: 390-399, 2007. (Pubitemid 46135607)
27. -ΔΔCT method. Methods 25: 402-408, 2001.
28. Mazaki-Tovi S, Romero R, Kusanovic JP, et al: Adiponectin multimers in normal pregnancy. J Matern Fetal Neonatal Med 21: 796-815, 2008.
29. Sasaki TM and Sonnae A: Effect of acetic acid concentration on the color reaction in the otoluidine-boric acid method for blood glucose estimation. Rinsho Kagaku 1: 346-353, 1972.
30. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF and Turner RC: Homeostasis model assessment: insulin resistance and b-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28: 412-419, 1985.
31. Haffner SM, Kennedy E, Gonzalez C, Stern MP and Miettinen H: A prospective analysis of the HOMA model: the Mexico City Diabetes Study. Diabetes Care 19: 1138-1146, 1996.
32. Duncan MH, Singh BM, Wise PH, Carter G and Alaghband-Zadeh J: A single measure of insulin resistance in human disease. Lancet 346: 120-121, 1995.
33. Araki S, Dobashi K, Kubo K, Asayama K and Shirahata A: High molecular weight, rather than total, adiponectin levels better reflect metabolic abnormalities associated with childhood obesity. J Clin Endocrinol Metab 91: 5113-5116, 2006.
34. Katsuki A, Suematsu M, Gabazza EC, et al: Decreased high-molecular weight adiponectin-to-total adiponectin ratio in sera is associated with insulin resistance in Japanese metabolically obese, normal-weight men with normal glucose tolerance. Diabetes Care 29: 2327-2328, 2006. (Pubitemid 44899878)
35. Yamauchi T, Kamon J, Waki H, et al: The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med 7: 941-946, 2001.
36. Yamauchi T, Kamon J, Minokoshi Y, et al: Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat Med 8: 1288-1295, 2002. (Pubitemid 35373562)
37. Tomas E, Tsao TS, Saha AK, et al: Enhanced muscle fat oxidation and glucose transport by globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation. Proc Natl Sci USA 99: 16309-16313, 2002. (Pubitemid 35462791)
38. Melmed S: Medical progress: acromegaly. N Engl J Med 355: 2558-2573, 2006.