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Volumn 333, Issue 3, 2010, Pages 816-821

Novel anticytomegalovirus activity of immunosuppressant mizoribine and its synergism with ganciclovir

Author keywords

[No Author keywords available]

Indexed keywords

BENZIMIDAVIR; DEOXYGUANOSINE; FOSCARNET; GANCICLOVIR; GUANOSINE; INOSINATE DEHYDROGENASE; MIZORIBINE;

EID: 77952330764     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.109.160630     Document Type: Article
Times cited : (42)

References (38)
  • 1
    • 17844383984 scopus 로고    scopus 로고
    • Mizoribine in combination therapy with tacrolimus for living donor renal transplantation: Analysis of a nationwide study in Japan
    • DOI 10.1016/j.transproceed.2004.12.288
    • Akiyama T, Okazaki H, Takahashi K, Hasegawa A, Tanabe K, Uchida K, Takahara S, and Toma H (2005) Mizoribine in combination therapy with tacrolimus for living donor renal transplantation: analysis of a nationwide study in Japan. Transplant Proc 37:843-845. (Pubitemid 40590720)
    • (2005) Transplantation Proceedings , vol.37 , Issue.2 , pp. 843-845
    • Akiyama, T.1    Okazaki, H.2    Takahashi, K.3    Hasegawa, A.4    Tanabe, K.5    Uchida, K.6    Takahara, S.7    Toma, H.8
  • 2
    • 0034098326 scopus 로고    scopus 로고
    • Immunosuppressive drugs: The first 50 years and a glance forward
    • Allison AC (2000) Immunosuppressive drugs: the first 50 years and a glance forward. Immunopharmacology 47:63-83.
    • (2000) Immunopharmacology , vol.47 , pp. 63-83
    • Allison, A.C.1
  • 3
    • 0028998724 scopus 로고
    • GTP depletion induced by IMP dehydrogenase inhibitors blocks RNA-primed DNA synthesis
    • Catapano CV, Dayton JS, Mitchell BS, and Fernandes DJ (1995) GTP depletion induced by IMP dehydrogenase inhibitors blocks RNA-primed DNA synthesis. Mol Pharmacol 47:948-955.
    • (1995) Mol Pharmacol , vol.47 , pp. 948-955
    • Catapano, C.V.1    Dayton, J.S.2    Mitchell, B.S.3    Fernandes, D.J.4
  • 4
    • 0023928264 scopus 로고
    • A human cytomegalovirus function inhibits replication of herpes simplex virus
    • Cockley KD, Shiraki K, and Rapp F (1988) A human cytomegalovirus function inhibits replication of herpes simplex virus. J Virol 62:188-195. (Pubitemid 18050808)
    • (1988) Journal of Virology , vol.62 , Issue.1 , pp. 188-195
    • Cockley, K.D.1    Shiraki, K.2    Rapp, F.3
  • 5
    • 0027094084 scopus 로고
    • Comparison of the effects of mizoribine with those of azathioprine, 6-mercaptopurine, and mycophenolic acid on T lymphocyte proliferation and purine ribonucleotide metabolism
    • Dayton JS, Turka LA, Thompson CB, and Mitchell BS (1992) Comparison of the effects of mizoribine with those of azathioprine, 6-mercaptopurine, and mycophenolic acid on T lymphocyte proliferation and purine ribonucleotide metabolism. Mol Pharmacol 41:671-676.
    • (1992) Mol Pharmacol , vol.41 , pp. 671-676
    • Dayton, J.S.1    Turka, L.A.2    Thompson, C.B.3    Mitchell, B.S.4
  • 7
    • 0029006409 scopus 로고
    • Placebo-controlled study of mycophenolate mofetil combined with cyclosporin and cortico-steroids for prevention of acute rejection
    • European Mycophenolate Mofetil Cooperative Study Group European Mycophenolate Mofetil Cooperative Study Group
    • European Mycophenolate Mofetil Cooperative Study Group (1995) Placebo-controlled study of mycophenolate mofetil combined with cyclosporin and cortico-steroids for prevention of acute rejection. European Mycophenolate Mofetil Cooperative Study Group. Lancet 345:1321-1325.
    • (1995) Lancet , vol.345 , pp. 1321-1325
  • 8
    • 0029919822 scopus 로고    scopus 로고
    • Mycophenolate mofetil for maintenance therapy in kidney transplantation
    • Gonwa TA (1996) Mycophenolate mofetil for maintenance therapy in kidney transplantation. Clin Transplant 10:128-130. (Pubitemid 26076443)
    • (1996) Clinical Transplantation , vol.10 , Issue.1 , pp. 128-130
    • Gonwa, T.A.1
  • 10
    • 0021083308 scopus 로고
    • Genetic and biochemical studies on the activation and cytotoxic mechanism of bredinin, a potent inhibitor of purine biosynthesis in mammalian cells
    • DOI 10.1016/0006-2952(83)90301-5
    • Koyama H and Tsuji M (1983) Genetic and biochemical studies on the activation and cytotoxic mechanism of bredinin, a potent inhibitor of purine biosynthesis in mammalian cells. Biochem Pharmacol 32:3547-3553. (Pubitemid 14205362)
    • (1983) Biochemical Pharmacology , vol.32 , Issue.23 , pp. 3547-3553
    • Koyama, H.1    Tsuji, M.2
  • 12
    • 0348230333 scopus 로고    scopus 로고
    • Synergistic antiherpetic effect of acyclovir and mycophenolate mofetil following keratoplasty in patients with herpetic eye disease: First results of a randomised pilot study
    • DOI 10.1007/s00417-003-0724-7
    • Mayer K, Reinhard T, Reis A, Voiculescu A, and Sundmacher R (2003) Synergistic antiherpetic effect of acyclovir and mycophenolate mofetil following keratoplasty in patients with herpetic eye disease: first results of a randomised pilot study. Graefes Arch Clin Exp Ophthalmol 241:1051-1054. (Pubitemid 38028902)
    • (2003) Graefe's Archive for Clinical and Experimental Ophthalmology , vol.241 , Issue.12 , pp. 1051-1054
    • Mayer, K.1    Reinhard, T.2    Reis, A.3    Voiculescu, A.4    Sundmacher, R.5
  • 13
    • 0034082485 scopus 로고    scopus 로고
    • The use of mycophenolate mofetil in transplant recipients
    • DOI 10.1016/S0162-3109(00)00190-9, PII S0162310900001909
    • Mele TS and Halloran PF (2000) The use of mycophenolate mofetil in transplant recipients. Immunopharmacology 47:215-245. (Pubitemid 30394540)
    • (2000) Immunopharmacology , vol.47 , Issue.2-3 , pp. 215-245
    • Mele, T.S.1    Halloran, P.F.2
  • 14
    • 0030833601 scopus 로고    scopus 로고
    • Inhibition of calcium-induced insulin secretion from intact HIT-T15 or INS-1beta cells by GTP depletion
    • DOI 10.1016/S0006-2952(97)00057-9, PII S0006295297000579
    • Meredith M, Li G, and Metz SA (1997) Inhibition of calcium-induced insulin secretion from intact HIT-T15 or INS-1 beta cells by GTP depletion. Biochem Pharmacol 53:1873-1882. (Pubitemid 27356060)
    • (1997) Biochemical Pharmacology , vol.53 , Issue.12 , pp. 1873-1882
    • Meredith, M.1    Li, G.2    Metz, S.A.3
  • 15
    • 85047684168 scopus 로고    scopus 로고
    • Inosine-5′-monophosphate dehydrogenase is required for mitogenic competence of transformed pancreatic beta cells
    • DOI 10.1210/en.142.1.193
    • Metz S, Holland S, Johnson L, Espling E, Rabaglia M, Segu V, Brockenbrough JS, and Tran PO (2001) Inosine-5′-monophosphate dehydrogenase is required for mitogenic competence of transformed pancreatic beta cells. Endocrinology 142:193-204. (Pubitemid 32183681)
    • (2001) Endocrinology , vol.142 , Issue.1 , pp. 193-204
    • Metz, S.1    Holland, S.2    Johnson, L.3    Espling, E.4    Rabaglia, M.5    Segu, V.6    Scott Brockenbrough, J.7    Tran, P.O.8
  • 16
    • 0031952851 scopus 로고    scopus 로고
    • The novel immunosuppressive agent mycophenolate mofetil markedly potentiates the antiherpesvirus activities of acyclovir, ganciclovir, and penciclovir in vitro and in vivo
    • Neyts J, Andrei G, and De Clercq E (1998) The novel immunosuppressive agent mycophenolate mofetil markedly potentiates the antiherpesvirus activities of acyclovir, ganciclovir, and penciclovir in vitro and in vivo. Antimicrob Agents Chemother 42:216-222. (Pubitemid 28114421)
    • (1998) Antimicrobial Agents and Chemotherapy , vol.42 , Issue.2 , pp. 216-222
    • Neyts, J.1    Andrei, G.2    De Clercq, E.3
  • 17
    • 0032402248 scopus 로고    scopus 로고
    • Mycophenolate mofetil strongly potentiates the anti-herpesvirus activity of acyclovir
    • DOI 10.1016/S0166-3542(98)00047-3, PII S0166354298000473
    • Neyts J and De Clercq E (1998) Mycophenolate mofetil strongly potentiates the anti-herpesvirus activity of acyclovir. Antiviral Res 40:53-56. (Pubitemid 28535171)
    • (1998) Antiviral Research , vol.40 , Issue.1-2 , pp. 53-56
    • Neyts, J.1    De Clercq, E.2
  • 18
    • 50849144701 scopus 로고    scopus 로고
    • Case report: Persistent cytomegalovirus (CMV) infection after haploidentical hematopoietic stem cell transplantation using in vivo alemtuzumab: emergence of resistant CMV due to mutations in the UL97 and UL54 genes
    • Oshima K, Kanda Y, Kako S, Asano-Mori Y, Watanabe T, Motokura T, Chiba S, Shiraki K, and KurokawaM(2008) Case report: persistent cytomegalovirus (CMV) infection after haploidentical hematopoietic stem cell transplantation using in vivo alemtuzumab: emergence of resistant CMV due to mutations in the UL97 and UL54 genes. J Med Virol 80:1769-1775.
    • (2008) J Med Virol , vol.80 , pp. 1769-1775
    • Oshima, K.1    Kanda, Y.2    Kako, S.3    Asano-Mori, Y.4    Watanabe, T.5    Motokura, T.6    Chiba, S.7    Shiraki, K.8    Kurokawa, M.9
  • 19
    • 0032815361 scopus 로고    scopus 로고
    • Mycophenolic acid as acyclovir partner for combined inhibition of herpes viruses
    • Pancheva S, Roeva I, Dundarova D, and Remichkova M (1999) Mycophenolic acid as acyclovir partner for combined inhibition of herpes viruses. Pharmazie 54:632-633. (Pubitemid 29393230)
    • (1999) Pharmazie , vol.54 , Issue.8 , pp. 632-633
    • Pancheva, S.1    Roeva, I.2    Dundarova, D.3    Remichkova, M.4
  • 20
    • 0031405393 scopus 로고    scopus 로고
    • Antiherpetic activity of acyclovir is potentiated by mycophenolic acid [2]
    • Pancheva SN, Roeva IG, and Remichkova MG (1997) Antiherpetic activity of acyclovir is potentiated by mycophenolic acid. Acta Virol 41:357-358. (Pubitemid 28097335)
    • (1997) Acta Virologica , vol.41 , Issue.6 , pp. 357-358
    • Pancheva, S.N.1    Roeva, I.G.2    Remichkova, M.G.3
  • 22
    • 67650911368 scopus 로고    scopus 로고
    • Function of human cytomegalovirus UL97 kinase in viral infection and its inhibition by maribavir
    • Prichard MN (2009) Function of human cytomegalovirus UL97 kinase in viral infection and its inhibition by maribavir. Rev Med Virol 19:215-229.
    • (2009) Rev Med Virol , vol.19 , pp. 215-229
    • Prichard, M.N.1
  • 23
    • 0026293044 scopus 로고
    • Acyclovir: Mechanism of antiviral action and potentiation by ribonucleotide reductase inhibitors
    • Reardon JE and Spector T (1991) Acyclovir: mechanism of antiviral action and potentiation by ribonucleotide reductase inhibitors. Adv Pharmacol 22:1-27.
    • (1991) Adv Pharmacol , vol.22 , pp. 1-27
    • Reardon, J.E.1    Spector, T.2
  • 29
    • 0029115531 scopus 로고
    • Mycophenolate mofetil for the prevention of acute rejection in primary cadaveric renal allograft recipients
    • U.S. Renal Transplant Mycophenolate Mofetil Study Group
    • Sollinger HW (1995) Mycophenolate mofetil for the prevention of acute rejection in primary cadaveric renal allograft recipients. U.S. Renal Transplant Mycophenolate Mofetil Study Group. Transplantation 60:225-232.
    • (1995) Transplantation , vol.60 , pp. 225-232
    • Sollinger, H.W.1
  • 32
    • 33748301929 scopus 로고    scopus 로고
    • Synergistic antiviral activity of acyclovir and vidarabine against herpes simplex virus types 1 and 2 and varicella-zoster virus
    • DOI 10.1016/j.antiviral.2006.05.001, PII S0166354206001331
    • Suzuki M, Okuda T, and Shiraki K (2006) Synergistic antiviral activity of acyclovir and vidarabine against herpes simplex virus types 1 and 2 and varicella-zoster virus. Antiviral Res 72:157-161. (Pubitemid 44332567)
    • (2006) Antiviral Research , vol.72 , Issue.2 , pp. 157-161
    • Suzuki, M.1    Okuda, T.2    Shiraki, K.3
  • 33
    • 0028815323 scopus 로고
    • Pilot study of mycophenolate mofetil (RS-61443) in the prevention of acute rejection following renal transplantation in Japanese patients
    • RS-61443 Investigation Committee-Japan
    • Takahashi K, Ochiai T, Uchida K, Yasumura T, Ishibashi M, Suzuki S, Otsubo O, Isono K, Takagi H, and Oka T (1995) Pilot study of mycophenolate mofetil (RS-61443) in the prevention of acute rejection following renal transplantation in Japanese patients. RS-61443 Investigation Committee-Japan. Transplant Proc 27:1421-1424.
    • (1995) Transplant Proc , vol.27 , pp. 1421-1424
    • Takahashi, K.1    Ochiai, T.2    Uchida, K.3    Yasumura, T.4    Ishibashi, M.5    Suzuki, S.6    Otsubo, O.7    Isono, K.8    Takagi, H.9    Oka, T.10
  • 35
    • 0006986048 scopus 로고    scopus 로고
    • A blinded, randomized clinical trial of mycophenolate mofetil for the prevention of acute rejection in cadaveric renal transplantation
    • The Tricontinental Mycophenolate Mofetil Renal Transplantation Study Group. The Tricontinental Mycophenolate Mofetil Renal Transplantation Study Group
    • The Tricontinental Mycophenolate Mofetil Renal Transplantation Study Group. (1996) A blinded, randomized clinical trial of mycophenolate mofetil for the prevention of acute rejection in cadaveric renal transplantation. The Tricontinental Mycophenolate Mofetil Renal Transplantation Study Group. Transplantation 61:1029-1037.
    • (1996) Transplantation , vol.61 , pp. 1029-1037
  • 36
    • 0036119428 scopus 로고    scopus 로고
    • Role of mizoribine in renal transplantation
    • Tsuzuki K (2002) Role of mizoribine in renal transplantation. Pediatr Int 44:224-231.
    • (2002) Pediatr Int , vol.44 , pp. 224-231
    • Tsuzuki, K.1
  • 37
    • 0025821616 scopus 로고
    • Guanine ribonucleotide depletion inhibits T cell activation. Mechanism of action of the immunosuppressive drug mizoribine
    • Turka LA, Dayton J, Sinclair G, Thompson CB, and Mitchell BS (1991) Guanine ribonucleotide depletion inhibits T cell activation. Mechanism of action of the immunosuppressive drug mizoribine. J Clin Invest 87:940-948.
    • (1991) J Clin Invest , vol.87 , pp. 940-948
    • Turka, L.A.1    Dayton, J.2    Sinclair, G.3    Thompson, C.B.4    Mitchell, B.S.5


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