CASP8 polymorphisms contribute to cancer susceptibility: Evidence from a meta-analysis of 23 publications with 55 individual studies

Carcinogenesis

Volumn 31, Issue 5, 2010, Pages 850-857

  Yin, Ming ^a   Yan, Jingrong ^b   Wei, Sheng ^a   Wei, Qingyi ^a  

^a UNIVERSITY OF TEXAS   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 8; CASP8 PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; BLADDER CANCER; BRAIN TUMOR; BREAST CANCER; CANCER RISK; CANCER SUSCEPTIBILITY; CAUCASIAN; COLORECTAL CANCER; CONTROLLED STUDY; DNA POLYMORPHISM; DOMINANT GENE; ETHNICITY; EXON; GENE DELETION; GENOTYPE; HEAD AND NECK CANCER; HOMOZYGOSITY; HUMAN; LEUKEMIA; LUNG CANCER; LYMPHOMA; MAJOR CLINICAL STUDY; MENINGIOMA; MULTIPLE CANCER; MULTIPLE MYELOMA; OVARY CANCER; PANCREAS CANCER; PRIORITY JOURNAL; RECESSIVE GENE; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETICS; META ANALYSIS; NEOPLASM;

CASPASE 8; GENE DELETION; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; NEOPLASMS; POLYMORPHISM, GENETIC;

EID: 77952315915     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgq047     Document Type: Article

References (49)

1. Krelin, Y. et al. (2008) Caspase-8 deficiency facilitates cellular transformation in vitro. Cell Death Differ., 15, 1350-1355.
2. Podgorski, I. et al. (2006) Loss of caspase-8 in tumor cells: mechanism to overcome integrin-mediated death? Mol. Interv., 6, 132-136.
3. Lamkanfi, M. et al. (2007) Caspases in cell survival, proliferation and differentiation. Cell Death Differ., 14, 44-55.
4. Grenet, J. et al. (1999) Structure and chromosome localization of the human CASP8 gene. Gene, 226, 225-232.
5. MacPherson, G. et al. (2004) Association of a common variant of the CASP8 gene with reduced risk of breast cancer. J. Natl Cancer Inst., 96, 1866-1869.
6. Sun, T. et al. (2007) A six-nucleotide insertion-deletion polymorphism in the CASP8 promoter is associated with susceptibility to multiple cancers. Nat. Genet., 39, 605-613.
7. Kuersten, S. et al. (2003) The power of the 3′ UTR: translational control and development. Nat. Rev. Genet., 4, 626-637.
8. Rajaraman, P. et al. (2007) Polymorphisms in apoptosis and cell cycle control genes and risk of brain tumors in adults. Cancer Epidemiol. Biomarkers Prev., 16, 1655-1661.
9. Haiman, C.A. et al. (2008) A promoter polymorphism in the CASP8 gene is not associated with cancer risk. Nat. Genet., 40, 259-260; (author reply 260-261).
10. Sergentanis, T.N. et al. (2009) Association of two CASP8 polymorphisms with breast cancer risk: a meta-analysis. Breast Cancer Res. Treat, 120, 229-234.
11. Bethke, L. et al. (2009) CASP8 D302H and meningioma risk: an analysis of five case-control series. Cancer Lett., 273, 312-315.
12. Cox, A. et al. (2007) A common coding variant in CASP8 is associated with breast cancer risk. Nat. Genet., 39, 352-358.
13. Bethke, L. et al. (2008) The common D302H variant of CASP8 is associated with risk of glioma. Cancer Epidemiol. Biomarkers Prev., 17, 987-989.
14. Qiu, D. et al. (2005) Overview of the epidemiology of pancreatic cancer focusing on the JACC Study. J Epidemiol, 15 (suppl. 2), S157-S67.
15. Wei, Q. et al. (2000) Repair of tobacco carcinogen-induced DNA adducts and lung cancer risk: a molecular epidemiologic study. J. Natl Cancer Inst., 92, 1764-1772.
16. Cohen, S.M. et al. (2000) Epidemiology and etiology of premalignant and malignant urothelial changes. Scand. J. Urol. Nephrol. Suppl., 205, 105-115.
17. Blot, W.J. et al. (1988) Smoking and drinking in relation to oral and pharyngeal cancer. Cancer Res., 48, 3282-3287.
18. Au, W.W. et al. (2007) Environmental risk factors for prevention and molecular intervention of cervical cancer. Int. J. Hyg. Environ. Health, 210, 671-678.
19. Persson, I. (2000) Estrogens in the causation of breast, endometrial and ovarian cancers-evidence and hypotheses from epidemiological findings. J. Steroid Biochem. Mol. Biol., 74, 357-364.
20. DerSimonian, R. et al. (1986) Meta-analysis in clinical trials. Control Clin. Trials, 7, 177-188.
21. Egger, M. et al. (1997) Bias in meta-analysis detected by a simple, graphical test. BMJ, 315, 629-634.
22. Xu, H.L. et al. (2009) Polymorphisms and haplotypes in the caspase-3, caspase-7, and caspase-8 genes and risk for endometrial cancer: a population-based, case-control study in a Chinese population. Cancer Epidemiol. Biomarkers Prev., 18, 2114-2122.
23. De Vecchi, G. et al. (2009) Evidences for association of the CASP8 -652 6N del promoter polymorphism with age at diagnosis in familial breast cancer cases. Breast Cancer Res. Treat., 113, 607-608.
24. Ulybina, Y.M. et al. (2009) Coding polymorphisms in Casp5, Casp8 and DR4 genes may play a role in predisposition to lung cancer. Cancer Lett., 278, 183-191.
25. Shephard, N.D. et al. (2009) A breast cancer risk haplotype in the caspase-8 gene. Cancer Res., 69, 2724-2728.
26. Li, C. et al. (2010) The six-nucleotide deletion/insertion variant in the CASP8 promoter region is inversely associated with risk of squamous cell carcinoma of the head and neck. Cancer Prev. Res., 3, 246-253.
27. Frank, B. et al. (2005) Re: association of a common variant of the CASP8 gene with reduced risk of breast cancer. J. Natl Cancer Inst., 97, 1012L; (author reply 1012-1013).
28. Son, J.W. et al. (2006) Polymorphisms in the caspase-8 gene and the risk of lung cancer. Cancer Genet. Cytogenet., 169, 121-7.
29. Lan, Q. et al. (2007) Genetic variants in caspase genes and susceptibility to non-Hodgkin lymphoma. Carcinogenesis, 28, 823-827.
30. Sigurdson, A.J. et al. (2007) Polymorphisms in apoptosis-and proliferation-related genes, ionizing radiation exposure, and risk of breast cancer among U.S. Radiologic Technologists. Cancer Epidemiol. Biomarkers Prev., 16, 2000-2007.
31. Li, C. et al. (2008) Genetic variants and haplotypes of the caspase-8 and caspase-10 genes contribute to susceptibility to cutaneous melanoma. Hum. Mutat., 29, 1443-1451.
32. Cybulski, C. et al. (2008) A six-nucleotide deletion in the CASP8 promoter is not associated with a susceptibility to breast and prostate cancers in the Polish population. Breast Cancer Res. Treat., 112, 367-368.
33. Enjuanes, A. et al. (2008) Genetic variants in apoptosis and immuno-regulation-related genes are associated with risk of chronic lymphocytic leukemia. Cancer Res., 68, 10178-10186.
34. Frank, B. et al. (2008) The CASP8 -652 6N del promoter polymorphism and breast cancer risk: a multicenter study. Breast Cancer Res. Treat., 111, 139-144.
35. Pittman, A.M. et al. (2008) CASP8 variants D302H and -652 6N ins/del do not influence the risk of colorectal cancer in the United Kingdom population. Br. J. Cancer, 98, 1434-1436.
36. Hosgood, H.D.3rd et al. (2008) Caspase polymorphisms and genetic susceptibility to multiple myeloma. Hematol. Oncol., 26, 148-151.
37. Yang, M. et al. (2008) Functional variants in cell death pathway genes and risk of pancreatic cancer. Clin. Cancer Res., 14, 3230-3236.
38. Ramus, S.J. et al. (2008) Consortium analysis of 7 candidate SNPs for ovarian cancer. Int. J. Cancer, 123, 380-388.
39. Wang, M. et al. (2009) A six-nucleotide insertion-deletion polymorphism in the CASP8 promoter associated with risk and progression of bladder cancer. Clin. Cancer Res., 15, 2567-2572.
40. Gangwar, R. et al. (2009) Caspase 9 and caspase 8 gene polymorphisms and susceptibility to bladder cancer in north Indian population. Ann. Surg. Oncol., 16, 2028-2034.
41. Lan, Q. et al. (2009) Genetic variation in caspase genes and risk of non-Hodgkin lymphoma: a pooled analysis of 3 population-based case-control studies. Blood, 114, 264-267.
42. Gilot, D. et al. (2005) A role for caspase-8 and c-FLIPL in proliferation and cell-cycle progression of primary hepatocytes. Carcinogenesis, 26, 2086-2094.
43. Martinez, R. et al. (2007) CpG island promoter hypermethylation of the proapoptotic gene caspase-8 is a common hallmark of relapsed glioblastoma multiforme. Carcinogenesis, 28, 1264-1268.
44. Fulda, S. et al. (2001) Sensitization for death receptoror drug-induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer. Oncogene, 20, 5865-5877.
45. Sasco, A.J. et al. (2004) Tobacco smoking and cancer: a brief review of recent epidemiological evidence. Lung Cancer, 45 (suppl. 2), S3-S9.
46. Song, R.X. et al. (2003) Apoptotic action of estrogen. Apoptosis, 8, 55-60.
47. Zhong, C.Y. et al. (2008) NF-kappaB inhibition is involved in tobacco smoke-induced apoptosis in the lungs of rats. Toxicol. Appl. Pharmacol., 230, 150-158.
48. Lobanova, Y.S. et al. (2007) Mechanism of estrogen-induced apoptosis in breast cancer cells: role of the NF-kappaB signaling pathway. Biochemistry (Mosc), 72, 320-327.
49. Hirschhorn, J.N. et al. (2002) A comprehensive review of genetic association studies. Genet. Med., 4, 45-61.