Age-dependent changes in dopaminergic neuron firing patterns in substantia nigra pars compacta

Journal of Neural Transmission, Supplementa

Volumn , Issue 73, 2009, Pages 129-133

  Ishida, Yoshiyuki ^a   Kozaki, Tatsuya ^b   Isomura, Yoshikazu ^c   Ito, Sachiko ^b   Isobe, Ken Ichi ^a,b  

^a NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

^b NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

Author keywords

Aging; Electrophysiology; F344 rat; Firing pattern; Substantia nigra pars compacta

Indexed keywords

AGING; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; MALE; MOTOR CONTROL; MOTOR PERFORMANCE; NERVOUS SYSTEM ELECTROPHYSIOLOGY; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; PRIORITY JOURNAL; RAT; SINGLE UNIT ACTIVITY; SPIKE WAVE; SUBSTANTIA NIGRA; ACTION POTENTIAL; ANIMAL; BIOLOGICAL MODEL; CYTOLOGY; ELECTROENCEPHALOGRAPHY; FISCHER 344 RAT; METABOLISM; METHODOLOGY; NERVE CELL; NONLINEAR SYSTEM; PHYSIOLOGY;

DOPAMINE;

ACTION POTENTIALS; AGING; ANIMALS; DOPAMINE; ELECTROENCEPHALOGRAPHY; MALE; MODELS, NEUROLOGICAL; NEURONS; NONLINEAR DYNAMICS; RATS; RATS, INBRED F344; SUBSTANTIA NIGRA;

EID: 77952310336     PISSN: 03036995     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-211-92660-4_10     Document Type: Article

References (18)

1. Bilbao G, Ruiz-Ortega JA, Miguens N, Ulibarri I, Linazasoro G, Gómez-Urquijo S, Garibi J, Ugedo L (2006) Electrophysiological characterizaion of substantia nigra dopaminergic neurons in partially lesioned rats: Effect of subthalamotomy and levodopa treatment. Brain Res 1084(1):175-184
2. Campbell A, Baldessarini RJ, Stoll A, Teicher MH, Maynard P (1984) Effect of age on behavioral responses and tissue levels of apomorphine in the rat. Neuropharmacology 23 (7 A): 725-730
3. Chergui K, Suaud-Chagny MF, Gonon F (1994) Nonlinear relationship between impulse flow, dopamine release and dopamine elimination in the rat brain in vivo. Neuroscience 62(3):641-645
4. Deniau JM, Hammond C, Riszk A, Feger J (1978) Electrophysiological properties of identified output neurons of the rat substantia nigra (pars compacta and pars reticulata): evidences for the existence of branched neurons. Exp Brain Res 32:409-422
5. Freeman AS, Kelland MD, Rouillard C, Chiodo LA (1989) Electrophysiological characteristics and pharmacological responsiveness of midbrain dopaminergic neurons of the aged rat. J Pharmacol Exp Ther 249(3):790-797
6. Freeman AS, Meltzer LT, Bunny BS (1985) Firing properties of substantia nigra dopaminergic neurons in freely moving rats. Life Sci. 36(20):1983-1994
7. Gonon FG (1988) Nonlinear relationship between impulse flow and dopamine released by rat midbrain dopaminergic neurons as studied by in vivo electrochemistry. Neuroscience 24(1):19-28
8. Grace AA, Bunney BS (1984) The control of firing pattern in nigral dopamine neurons: burst firing. J Neurosci 4(11):2877-2890
9. Guyenet PG, Aghajanian GK (1978) Antidromic identification of dopaminergic and other output neurons of the rat substantia nigra. Brain Res 150:69-84
10. Hebert MA, Gerhardt GA (1998) Normal and drug-induced locomotor behavior in aging: comparison to evoked DA release and tissue content in fischer 344 rats. Brain Res 797(1):42-54
11. Hyland BI, Reynolds JN, Hay J, Perk CG, Miller R (2002) Firing modes of midbrain dopamine cells in the freely moving rat. Neuroscience 114:475-492
12. Ishida Y, Okawa Y, Ito S, Shirokawa T, Isobe K (2007) Age-dependent changes in dopaminergic projections from the substantia nigra pars compacta to the neostriatum. Neurosci Lett 418(3):257-261
13. Payne AP, Campbell JM, Russell D, Favor G, Sutcliffe RG, Bennett NK, Davies RW, Stone TW (2000) The AS/AGU rat: a spontaneous model of disruption and degeneration in the nigrostriatal dopaminergic system. J Anat 196:629-633
14. Sakata M, Farooqui SM, Prasad C (1992) Post-transcriptional regulation of loss of rat striatal D2 dopamine receptor during aging. Brain Res 575(2):309-314
15. Schultz W, Dayan P, Montague PR (1997) A neural substrate of prediction and reward. Science 275(5306):1593-1599
16. Suzuki M, Hatano K, Sakiyama Y, Kawasumi Y, Kato T, Ito K (2001) Age-related changes of dopamine D1-like and D2-like receptor binding in the F344/N rat striatum revealed by positron emission tomography and in vitro receptor autoradiography. Synapse 41(4):285-293
17. Tepper JM, Martin LP, Anderson DR (1995) GABAA receptormediated inhibition of rat substantia nigra dopaminergic neurons by pars reticulata projection neurons. J Neurosci 15(4):3092-3103
18. Wilson CJ, Young SJ, Groves PM (1977) Statistical properties of neuronal spike trains in the substantia nigra: cell types and their interactions. Brain Res 136(2):243-260