Effect of emulsifiers and their liquid crystalline structures in emulsions on dermal and transdermal delivery of hydroquinone, salicylic acid and octadecenedioic acid

Skin Pharmacology and Physiology

Volumn 23, Issue 5, 2010, Pages 273-282

  Otto, A ^a   Wiechers, J W ^b,d   Kelly, C L ^c   Dederen, J C ^e   Hadgraft, J ^a,d   Du Plessis, J ^a  

^a NORTH WEST UNIVERSITY   (South Africa)

^b JW Solutions   (Netherlands)

^c Uniqema Applied Research   (United Kingdom)

^d UNIVERSITY OF LONDON   (United Kingdom)

^e Uniqema Applied Research   (Belgium)

Author keywords

Dermal delivery; Emulsifier; Emulsion; Flux; Liquid crystalline phase; Transdermal delivery

Indexed keywords

ARLATONE; EMULSIFYING AGENT; ESSENTIAL FATTY ACID; HYDROQUINONE; OCTADECENEDIOIC ACID; OLEIC ACID; PHOSPHATIDYLCHOLINE; SALICYLIC ACID; UNCLASSIFIED DRUG; DICARBOXYLIC ACID; EMULSION; EXCIPIENT; HYDROQUINONE DERIVATIVE;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DERMATOME; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG EFFECT; DRUG FORMULATION; DRUG SOLUBILITY; DRUG STRUCTURE; EMULSION; FEMALE; HUMAN; HUMAN TISSUE; INTRADERMAL DRUG ADMINISTRATION; LIQUID CRYSTAL; PARTITION COEFFICIENT; PRIORITY JOURNAL; SKIN; SKIN ABSORPTION; SKIN PENETRATION; SKIN PERMEABILITY; THICKNESS; TRANSDERMAL DRUG ADMINISTRATION; CHEMISTRY; CRYSTALLIZATION; IN VITRO STUDY; PERMEABILITY; SOLUBILITY;

ADMINISTRATION, CUTANEOUS; CRYSTALLIZATION; DICARBOXYLIC ACIDS; EMULSIONS; EXCIPIENTS; FEMALE; HUMANS; HYDROQUINONES; PERMEABILITY; SALICYLIC ACID; SKIN ABSORPTION; SOLUBILITY; IN VITRO TECHNIQUES;

EID: 77952308598     PISSN: 16605527     EISSN: None     Source Type: Journal    
DOI: 10.1159/000314702     Document Type: Article

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