Natural surfactant-based topical vehicles for two model drugs: Influence of different lipophilic excipients on in vitro/in vivo skin performance

International Journal of Pharmaceutics

Volumn 381, Issue 2, 2009, Pages 220-230

  Savić, Snežana ^a   Weber, Christian ^b   Savić, Miroslav M ^a   Müller Goymann, Christel ^b  

^a Faculty of Pharmacy   (Serbia)

^b TECHNICAL UNIVERSITY OF BRAUNSCHWEIG   (Germany)

Author keywords

Alkylpolyglucoside; Caffeine; Cytotoxicity assay; Decyl oleate; Diclofenac sodium; In vitro permeation; In vivo skin performance; Isopropyl myristate; Medium chain triglycerides; Mixed emulsifier; Natural surfactant based topical vehicles

Indexed keywords

CAFFEINE; CETOSTEARYLIC ALCOHOL; DICLOFENAC; MYRISTIC ACID ISOPROPYL ESTER; TRIACYLGLYCEROL;

ARTICLE; BIOSAFETY; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; EMULSION; EXCIPIENT COMPATIBILITY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIPOPHILICITY; MEMBRANE PERMEABILITY; NEWBORN; PRIORITY JOURNAL; SKIN IRRITATION; SKIN TEST;

ADMINISTRATION, CUTANEOUS; ADULT; CAFFEINE; CELL LINE; CELL SURVIVAL; CELLS, CULTURED; COLLOIDS; DICLOFENAC; DRUG COMPOUNDING; EXCIPIENTS; FATTY ALCOHOLS; FEMALE; FIBROBLASTS; GLYCOLIPIDS; HUMANS; HYDROGEN-ION CONCENTRATION; KERATINOCYTES; LIPIDS; PERMEABILITY; SKIN IRRITANCY TESTS; SKIN, ARTIFICIAL; SOLUBILITY; SURFACE-ACTIVE AGENTS; YOUNG ADULT;

EID: 70349400006     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2009.07.007     Document Type: Article

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