Surviving childhood and reproductive-age malignancy: Effects on fertility and future parenthood

The Lancet Oncology

Volumn 11, Issue 5, 2010, Pages 490-498

  Knopman, Jaime M ^a   Papadopoulos, Esperenza B ^b   Grifo, James A ^a   Fino, M Elizabeth ^a   Noyes, Nicole ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN; CHLORMETHINE; CYCLOPHOSPHAMIDE; DACARBAZINE; DOXORUBICIN; IMATINIB; PREDNISONE; PROCARBAZINE; TAMOXIFEN; VINBLASTINE; VINCRISTINE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADJUVANT THERAPY; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER SURVIVAL; CHILDHOOD CANCER; CHRONIC MYELOID LEUKEMIA; CONGENITAL MALFORMATION; ENDOCRINE DISEASE; FERTILITY; FERTILIZATION IN VITRO; GENETIC RISK; HODGKIN DISEASE; HUMAN; HYPOGONADISM; HYPOTHALAMUS HYPOPHYSIS GONAD SYSTEM; HYSTERECTOMY; INFERTILITY; NONHODGKIN LYMPHOMA; NONHUMAN; OVARY INSUFFICIENCY; OVARY TUMOR; PARENTHOOD; PREGNANCY OUTCOME; PRIORITY JOURNAL; PROGNOSIS; RADIATION SICKNESS; REPRODUCTION; REVIEW; RISK FACTOR; SKULL IRRADIATION; SPERMATOGENESIS; UTERINE CERVIX CANCER; ADOLESCENT; ADULT; CHILD; FEMALE; INFERTILITY THERAPY; MALE; MORTALITY; NEOPLASM; PARENT; SURVIVOR;

ADOLESCENT; ADULT; CHILD; FEMALE; FERTILITY; HUMANS; INFERTILITY; MALE; NEOPLASMS; PARENTS; REPRODUCTIVE TECHNIQUES, ASSISTED; SURVIVORS; YOUNG ADULT;

EID: 77952307861     PISSN: 14702045     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1470-2045(09)70317-1     Document Type: Review

References (78)

1. Schover LR, Rybicki LA, Martin BA, Bringelsen KA Having children after cancer: a pilot survey of survivors' attitudes and experiences. Cancer 1999, 86:530-535.
2. SEER Cancer Statistics Review National Cancer Institute, (accessed April 15, 2009). http://seer.cancer.gov/csr/1975_2006/index.html.
3. Maltaris T, Koelbl H, Seufert R, et al. Gonadal damage and options for fertility preservation in female and male cancer survivors. Asian J Androl 2006, 8:515-533.
4. Childhood Cancer Survivorship. Improving Care and Quality of Life 2003, The National Academies Press, Washington, DC. M. Hewitt, S.L. Weiner, J.V. Simone (Eds.).
5. Jemal A, Murray T, Samuels A, Ghafoor A, Ward E, Thun MJ Cancer statistics, 2003. CA Cancer J Clin 2003, 53:5-26.
6. Lee SJ, Schover LR, Partridge AH, et al. American Society of Clinical Oncology recommendations on fertility preservation in cancer patients. J Clin Oncol 2006, 24:1-16.
7. Gurgan T, Salman C, Demirol A Pregnancy and assisted reproduction techniques in men and women after cancer treatment. Placenta 2008, 29:152-159.
8. Rebar RW Premature ovarian failure. Obstet Gynecol 2009, 113:1355-1363.
9. Goodwin PJ, Ennis M, Pritchard KI, Trudeau M, Hood N Risk of menopause during the first year after breast cancer diagnosis. J Clin Oncol 1999, 17:2365-2370.
10. Wallace WH, Thomson AB, Kelsey TW The radiosensitivity of the human oocyte. Hum Reprod 2003, 18:117-121.
11. Hawkins MM, Smith RA Pregnancy outcomes in childhood cancer survivors: probable effects of abdominal irradiation. Int J Cancer 1989, 43:399-402.
12. Critchley HO, Bath LE, Wallace WH Radiation damage to the uterus-review of the effects of treatment of childhood cancer. Hum Fertil (Camb) 2002, 5:61-66.
13. Wo JY, Viswanathan AK Impact of radiotherapy on fertility, pregnancy, and neonatal outcomes in female cancer patients. Int J Radiat Oncol Biol Phys 2009, 5:1304-1312.
14. Skakkebaek NE, Rajpert-De Meyts E, Main KM Testicular dysgenesis syndrome: an increasingly common development disorder with environmental aspects. Hum Reprod 2001, 16:972-978.
15. Magelseen H, Brydoy M, Fossa SD The effects of cancer and cancer treatments on male reproductive function. Nat Clin Pract Urol 2006, 3:312-322.
16. Rueffer U, Breuer K, Josting A, et al. Male gonadal dysfunction in patients with Hodgkin's disease prior to treatment. Ann Oncol 2001, 12:1307-1311.
17. Mitchell RT, Saunders PTK, Sharpe RM, Kelnar CJH, Wallace WHB Male fertility and strategies for fertility preservation following childhood cancer treatment. Endocr Dev 2009, 15:101-134.
18. Thomson AB, Campbell AJ, Irvine DC, Anderson RA, Kelnar CJ, Wallace WH Semen quality and spermatozoal DNA integrity in survivors of childhood cancer: a case control study. Lancet 2002, 360:361-367.
19. Socie G, Salooja N, Cohen A, et al. Nonmalignant late effects after allogenic stem cell transplantation. Blood 2003, 101:3373-3385.
20. Martin RH, Hildebrand K, Yamamoto J, et al. An increased frequency of human sperm chromosomal abnormalities after radiotherapy. Mutat Res 1986, 174:219-225.
21. Green DM, Whitton JA, Stovall M, et al. Pregnancy outcome of partners of male survivors of childhood cancer: a report from the Childhood Cancer Survivor Study. J Clin Oncol 2003, 21:716-721.
22. Green DM, Whitton JA, Stovall M, et al. Pregnancy outcome of female survivors of childhood cancer: a report from the Childhood Cancer Survivor Study. Am J Obstet Gyencol 2002, 187:1070-1080.
23. Magelseen H, Melve KK, Skjaerven R, Fossa SD Parenthood probability and pregnancy outcome in patients with a cancer diagnosis during adolescence and young adulthood. Hum Reprod 2008, 23:178-189.
24. Madanat L-MS, Maliala N, Dyba T, et al. Probability of parenthood after early onset cancer: a population based study. Int J Cancer 2008, 123:2891-2898.
25. Cvancarova M, Samuelsen SO, Magelssen H, Fossa SD Reproduction rates after cancer treatment: experience from the Norwegian Radium Hospital. J Clin Oncol 2008, 27:334-343.
26. Plante M, Renaud MC, Hoskins IA, Roy M Vaginal radical trachelectomy: a valuable fertility-preserving option in the management of early-stage cervical cancer. A series of 50 pregnancies and review of the literature. Gynecol Oncol 2005, 98:3-10.
27. Noyes N, Abu-Rustum N, Ramirez PT, Plante M Options in the management of fertility-related issues after radical trachelectomy in patients with early cervical cancer. Gynecol Oncol 2009, 114:117-120.
28. Noyes N, Borini A, Porcu E Over 900 oocyte cryopreservation babies born with no apparent increase in congenital anomalies. Reprod Biomed Online 2009, 18:769-776.
29. Canellos GP, Anderson JR, Propert KJ, et al. Chemotherapy of advanced Hodgkin's disease with MOPP, ABVD or MOPP alternating with ABVD. N Engl J Med 1992, 327:1478-1484.
30. Hodgson D, Pintilie M, Gitterman L, et al. Fertility among female Hodgkin lymphoma survivors attempting pregnancy following ABVD chemotherapy. Hematol Oncol 2007, 25:11-15.
31. Viviani S, Santoro A, Ragni G, Bonfante V, Bestetti O, Bonadonna G Gonadal toxicity after combination chemotherapy for Hodgkin's disease. Comparative results of MOPP vs. ABVD. Eur J Cancer Clin Oncol 1985, 21:601-605.
32. Kiserud CE, Fossa A, Holte H, Fossa SD Post-treatment parenthood in Hodgkin's lymphoma survivors. Br J Cancer 2007, 9:1442-1449.
33. Clark ST, Radford JA, Crowther D, Swindell R, Shalet SM Gonadal function following chemotherapy for Hodgkin's disease: a comparative study of MVPP and a seven-drug hybrid regimen. J Clin Oncol 1995, 13:134-139.
34. Meirow D Ovarian injury and modern options to preserve fertility in female cancer patients treated with high dose radio-chemotherapy for hemato-oncological neoplasias and other cancers. Leuk Lymphoma 1999, 33:66-76.
35. Blumenfeld Z, von Wolff M GnRH-analogues and oral contraceptives for fertility preservation in women during chemotherapy. Hum Reprod Update 2008, 14:543-552.
36. Socie G, Salooja N, Cohen A, et al. Nonmalignant late affects after allogeneic stem cell transplantation. Blood 2003, 101:3373-3385.
37. Waring AB, Wallace WH Subfertility following treatment for childhood cancer. Hosp Med 2000, 61:550-557.
38. Bath LE, Anderson RA, Critchley HOD, Kelnar CJH, Wallace WHB Hypothalamic-pituitary-ovarian dysfunction after prepubertal chemotherapy and cranial irradiation for acute leukemia. Hum Reprod 2001, 16:1838-1844.
39. Nygaard R, Clausen N, Siimes MA, et al. Reproduction following treatment for childhood leukemia: a population based prospective cohort study of fertility and offspring. Med Pediatr Oncol 1991, 19:459-466.
40. Kromen N, Jensen MB, Wohlfahrt J, Ejlertsen B Pregnancy after treatment of breast cancer-a population-based study on behalf of Danish Breast Cancer Cooperative Group. Acta Oncologica 2008, 47:545-549.
41. Darzy KH Radiation-induced hypopituitarism after cancer therapy: who, how and when to test. Nature 2009, 5:88-99.
42. Rappaport R, Brauner R, Czernichow P, et al. Effect of hypothalamic and pituitary irradiation on pubertal development in children with cranial tumours. J Clin Endocrinol Metab 1982, 54:1164-1168.
43. Mansky P, Arai A, Stratton P, et al. Treatment late effects in long-term survivors of pediatric sarcoma. Pediatr Blood Cancer 2007, 48:192-199.
44. Hosalkar HS, Henderson KM, Weiss A, Donthineni R, Lackman RD Chemotherapy for bone sarcoma does not affect fertility rates or childbirth. Clin Orthop Relat Res 2004, 428:256-260.
45. Schover LR Rates of postcancer parenthood. J Clin Oncol 2009, 27:321-322.
46. Byrne J, Rasmussen SA, Steinhorn SC, et al. Genetic disease in offspring of long-term survivors of childhood and adolescent cancer. Am J Hum Genet 1998, 62:45-52.
47. Li FP, Fine W, Jaffe N, Holmes GE, Holmes FF Offspring of patients treated for cancer in childhood. J Natl Cancer Inst 1979, 62:1193-1197.
48. Boice JD, Tawn EJ, Winther JF, et al. Genetic effects of radiotherapy for childhood cancer. Health Phys 2003, 85:65-80.
49. Winther JF, Boice JD, Thomsen BL, Schull WJ, Stovall M, Olsen JH Sex ratio among offspring of childhood cancer survivors treated with radiotherapy. Br J Cancer 2003, 88:382-387.
50. Green DM, Peabody EM, Nan B, Peterson S, Kalapurakal JA, Breslow N Pregnancy outcome after treatment for Wilms tumour: a report from the National Wilms tumour study group. J Clin Oncol 2002, 20:2506-2513.
51. Diaz J, Sonoda Y, Leitao M, et al. Oncologic outcome of fertility-sparing radical trachelectomy vs. radical hysterectomy for stage 1B1 cervical carcinoma. Gynecol Oncol 2008, 111:255-260.
52. Wang CB, Wang CJ, Huang HJ, et al. Fertility-preserving treatment in young patients with endometrial adenocarcinoma. Cancer 2002, 94:2192-2198.
53. Chiva L, Lapuente F, Gonzalez-Cortijo L, et al. Sparing fertility in young patients with endometrial cancer. Gynecol Oncol 2008, 111:S101-S104.
54. Schilder JM, Thompson AM, DePriest PD, et al. Outcome of reproductive age women with stage IA or IC invasive epithelial ovarian cancer treated with fertility-sparing therapy. Gynecol Oncol 2002, 87:1-7.
55. Maltaris T, Boehm D, Dittrich R, Seufert R, Koebl H Reproduction beyond cancer. A message of hope for young women. Gynecol Oncol 2006, 103:1109-1121.
56. Belva F, Henriet S, Van den Abbeel E, et al. Neonatal outcome of 937 children born after transfer of cryopreserved embryos obtained by ICSI and IVF and comparison with outcome data of fresh ICSI and IVF cycles. Hum Reprod 2008, 23:2227-2238.
57. Grifo JA, Noyes N Delivery rate using cryopreserved oocytes is comparable to conventional in vitro fertilization using fresh oocytes: potential fertility preservation for female cancer patients. Fertil Steril 2009, 93:391-396.
58. Demeestere I, Simon P, Emiliani S, Delbaere A, Englert Y Fertility preservation: successful transplantation of cryopreserved ovarian tissue in a young patient previously treated for Hodgkin's disease. Oncologist 2007, 12:1437-1442.
59. Donnez J, Dolmans MM, Demylle D, et al. Livebirth after orthotopic transplantation of cryopreserved ovarian tissue. Lancet 2004, 364:1405-1410.
60. Meirow D, Levron J, Eldar-Geva T, et al. Pregnancy after transplantation of cryopreserved ovarian tissue in a patient with ovarian failure after chemotherapy. N Engl J Med 2005, 353:318-321.
61. Andersen CY, Rosendahl M, Byskov1 AG, et al. Two successful pregnancies following autotransplantation of frozen/thawed ovarian tissue. Hum Reprod 2008, 23:2266-2272.
62. Chan PT, Palermo GD, Veeck LL, Rosenwaks Z, Schlegal PN Testicular sperm extraction combined with intracytoplasmic sperm injection in the treatment of men with persistent azoospermia postchemotherapy. Cancer 2001, 92:1632-1637.
63. Hourvitz A, Goldschlag DE, Davis OK, Veeck Gosden L, Palermo GD, Rosenwaks Z Intracytoplasmic sperm injection (ICSI) using cryopreserved sperm from men with malignant neoplasm yields high pregnancy rates. Fertil Steril 2008, 90:557-563.
64. Blakely LJ, Buzdar AU, Lozada JA, et al. Effects of pregnancy after treatment for breast carcinoma on survival and risk of recurrence. Cancer 2004, 100:465-469.
65. Maltaris T, Weigel M, Mueller A, et al. Cancer and fertility preservation in breast cancer patients. Breast Cancer Res 2008, 10:206-216.
66. Kroman N, Jensen MB, Melbye M, Wohlfahrt J, Mouridsen HT Should women be advised against pregnancy after breast cancer treatment?. Lancet 1997, 350:319-322.
67. von Schoultz E, Johansson H, Wilking N, Rutqvist LE Influence of prior and subsequent pregnancy on breast cancer prognosis. J Clin Oncol 1995, 13:430-434.
68. Gelber S, Coates AS, Goldhirsch A, et al. Effect of pregnancy on overall survival after the diagnosis of early-stage breast cancer. J Clin Oncol 2001, 19:1671-1675.
69. Sankila R, Heinavaara S, Hakulinen T Survival of breast cancer patients after subsequent term pregnancy: " healthy mother effect." Am J Obstet Gynecol 1994, 170:818-823.
70. Clark RM, Chua T Breast cancer and pregnancy: the ultimate challenge. Clin Oncol 1989, 1:11-18.
71. Barthelmes L, Gateley CA Tamoxifen and pregnancy. The Breast 2004, 13:446-451.
72. Oktay K, Buyuk E, Libertella N, Akar M, Rosenwaks Z fertility preservation in breast cancer patients: a prospective controlled comparison of ovarian stimulation with tamoxifen and letrozole for embryo cryopreservation. J Clin Oncol 2005, 19:4347-4353.
73. Kotsopoulos J, Librach CL, Lubinski J, et al. Infertility, treatment of infertility, and the risk of breast cancer among women with BRCA1 and BRCA2 mutations: a case-control study. Cancer Causes Control 2008, 19:1111-1119.
74. Salooja N, Szydlo RM, Socie G, et al. Pregnancy outcomes after peripheral blood or bone marrow transplantation: a retrospective survey. Lancet 2001, 358:271-276.
75. Ali R, Ozkalemkas F, Kimya Y, Koksal N, Ozkocaman V, Gulten T Imatinib use during pregnancy and breast feeding: a case report and review of the literature. Arch Gynecol Obstet 2009, 280:169-175.
76. Vadaparampil S, Quinn G, King L, Wilson C, Nieder M Barriers to fertility preservation among pediatric oncologists. Patient Educ Couns 2008, 72:402-410.
77. Partridge AH, Gelber S, Peppercorn J, et al. Web-based survey of fertility issues in young women with breast cancer. J Clin Oncol 2004, 22:4174-4183.
78. Burns KC, Bourdreau C, Panepinto Attitudes regarding fertility preservation in female adolescent cancer patients. J Pediatr Hematol Oncol 2006, 28:350-354.