메뉴 건너뛰기




Volumn 635, Issue 1-3, 2010, Pages 177-183

Effect of cyclic AMP-elevating agents on airway ciliary beat frequency in central and lateral airways in rat precision-cut lung slices

Author keywords

Ciliary beat frequency; COPD; PDE4; Roflumilast

Indexed keywords

CYCLIC AMP; FORSKOLIN; ROFLUMILAST; ROLIPRAM; TERBUTALINE;

EID: 77952304047     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2010.03.005     Document Type: Article
Times cited : (13)

References (41)
  • 4
    • 0032159905 scopus 로고    scopus 로고
    • PKA induces Ca2+ release and enhances ciliary beat frequency in a Ca2+-dependent and -independent manner
    • Braiman A., Zagoory O., Priel Z. PKA induces Ca2+ release and enhances ciliary beat frequency in a Ca2+-dependent and -independent manner. Am. J. Physiol. 1998, 275:C790-C797.
    • (1998) Am. J. Physiol. , vol.275
    • Braiman, A.1    Zagoory, O.2    Priel, Z.3
  • 6
    • 69149103642 scopus 로고    scopus 로고
    • Roflumilast in symptomatic chronic obstructive pulmonary disease: two randomised clinical trials
    • Calverley P.M., Rabe K.F., Goehring U.-M., Kristiansen S., Fabbri L.M., Martinez F.J. Roflumilast in symptomatic chronic obstructive pulmonary disease: two randomised clinical trials. Lancet 2009, 374:685-694.
    • (2009) Lancet , vol.374 , pp. 685-694
    • Calverley, P.M.1    Rabe, K.F.2    Goehring, U.-M.3    Kristiansen, S.4    Fabbri, L.M.5    Martinez, F.J.6
  • 7
    • 33745593777 scopus 로고    scopus 로고
    • Ciliary beat frequency is maintained at a maximal rate in the small airways of mouse lung slices
    • Delmotte P., Sanderson M.J. Ciliary beat frequency is maintained at a maximal rate in the small airways of mouse lung slices. Am. J. Respir. Cell Mol. Biol. 2006, 35:110-117.
    • (2006) Am. J. Respir. Cell Mol. Biol. , vol.35 , pp. 110-117
    • Delmotte, P.1    Sanderson, M.J.2
  • 8
    • 0027080197 scopus 로고
    • The effects of salmeterol and salbutamol on ciliary beat frequency of cultured human bronchial epithelial cells, in vitro
    • Devalia J.L., Sapsford R.J., Rusznak C., Toumbis M.J., Davies R.J. The effects of salmeterol and salbutamol on ciliary beat frequency of cultured human bronchial epithelial cells, in vitro. Pulm. Pharmacol. 1992, 5:257-263.
    • (1992) Pulm. Pharmacol. , vol.5 , pp. 257-263
    • Devalia, J.L.1    Sapsford, R.J.2    Rusznak, C.3    Toumbis, M.J.4    Davies, R.J.5
  • 10
    • 69149098943 scopus 로고    scopus 로고
    • Roflumilast in moderate-to-severe chronic obstructive pulmonary disease treated with longacting bronchodilators: two randomised clinical trials
    • Fabbri L.M., Calverley P.M., Izquierdo-Alonso J.L., Bundschuh D.S., Brose M., Martinez F.J., Rabe K.F. Roflumilast in moderate-to-severe chronic obstructive pulmonary disease treated with longacting bronchodilators: two randomised clinical trials. Lancet 2009, 374:695-703.
    • (2009) Lancet , vol.374 , pp. 695-703
    • Fabbri, L.M.1    Calverley, P.M.2    Izquierdo-Alonso, J.L.3    Bundschuh, D.S.4    Brose, M.5    Martinez, F.J.6    Rabe, K.F.7
  • 11
    • 0019823136 scopus 로고
    • Effect of inhaled salbutamol on mucociliary clearance in patients with chronic bronchitis
    • Fazio F., Lafortuna C. Effect of inhaled salbutamol on mucociliary clearance in patients with chronic bronchitis. Chest 1981, 80:827-830.
    • (1981) Chest , vol.80 , pp. 827-830
    • Fazio, F.1    Lafortuna, C.2
  • 12
    • 0019781801 scopus 로고
    • Respiratory drugs influence lung mucociliary clearance in central and peripheral ciliated airways
    • Foster W.M., Langenback E.G., Bergofsky E.H. Respiratory drugs influence lung mucociliary clearance in central and peripheral ciliated airways. Chest 1981, 80:877-880.
    • (1981) Chest , vol.80 , pp. 877-880
    • Foster, W.M.1    Langenback, E.G.2    Bergofsky, E.H.3
  • 13
    • 27644589238 scopus 로고    scopus 로고
    • Phosphodiesterase-4: selective and dual-specificity inhibitors for the therapy of chronic obstructive pulmonary disease
    • Giembycz M.A. Phosphodiesterase-4: selective and dual-specificity inhibitors for the therapy of chronic obstructive pulmonary disease. Proc. Am. Thorac. Soc. 2005, 2:326-333.
    • (2005) Proc. Am. Thorac. Soc. , vol.2 , pp. 326-333
    • Giembycz, M.A.1
  • 14
    • 0035084103 scopus 로고    scopus 로고
    • Anti-inflammatory and immunomodulatory potential of the novel PDE4 inhibitor roflumilast in vitro
    • Hatzelmann A., Schudt C. Anti-inflammatory and immunomodulatory potential of the novel PDE4 inhibitor roflumilast in vitro. J. Pharmacol. Exp. Ther. 2001, 297:267-279.
    • (2001) J. Pharmacol. Exp. Ther. , vol.297 , pp. 267-279
    • Hatzelmann, A.1    Schudt, C.2
  • 15
    • 0034919019 scopus 로고    scopus 로고
    • Prostaglandin E2 activates the ciliary beat frequency of cultured human nasal mucosa via the second messenger cyclic adenosine monophosphate
    • Haxel B.R., Schafer D., Klimek L., Mann W.J. Prostaglandin E2 activates the ciliary beat frequency of cultured human nasal mucosa via the second messenger cyclic adenosine monophosphate. Eur. Arch. Otorhinolaryngol. 2001, 258:230-235.
    • (2001) Eur. Arch. Otorhinolaryngol. , vol.258 , pp. 230-235
    • Haxel, B.R.1    Schafer, D.2    Klimek, L.3    Mann, W.J.4
  • 17
    • 0028030876 scopus 로고
    • Ciliary beat frequency at six levels of the respiratory tract in cow, dog, guinea-pig, pig, rabbit and rat
    • Joki S., Saano V. Ciliary beat frequency at six levels of the respiratory tract in cow, dog, guinea-pig, pig, rabbit and rat. Clin. Exp. Pharmacol. Physiol 1994, 21:427-434.
    • (1994) Clin. Exp. Pharmacol. Physiol , vol.21 , pp. 427-434
    • Joki, S.1    Saano, V.2
  • 18
    • 0036194724 scopus 로고    scopus 로고
    • Mucus clearance as a primary innate defense mechanism for mammalian airways
    • Knowles M.R., Boucher R.C. Mucus clearance as a primary innate defense mechanism for mammalian airways. J. Clin. Invest. 2002, 109:571-577.
    • (2002) J. Clin. Invest. , vol.109 , pp. 571-577
    • Knowles, M.R.1    Boucher, R.C.2
  • 19
    • 1842854486 scopus 로고    scopus 로고
    • Characterization of an A-kinase anchoring protein in human ciliary axonemes
    • Kultgen P.L., Byrd S.K., Ostrowski L.E., Milgram S.L. Characterization of an A-kinase anchoring protein in human ciliary axonemes. Mol. Biol. Cell 2002, 13:4156-4166.
    • (2002) Mol. Biol. Cell , vol.13 , pp. 4156-4166
    • Kultgen, P.L.1    Byrd, S.K.2    Ostrowski, L.E.3    Milgram, S.L.4
  • 20
    • 0021324792 scopus 로고
    • Acute effect of inhaled salbutamol on mucociliary clearance in health and chronic bronchitis
    • Lafortuna C.L., Fazio F. Acute effect of inhaled salbutamol on mucociliary clearance in health and chronic bronchitis. Respiration 1984, 45:111-123.
    • (1984) Respiration , vol.45 , pp. 111-123
    • Lafortuna, C.L.1    Fazio, F.2
  • 21
    • 0032975045 scopus 로고    scopus 로고
    • Regulation of airway ciliary activity by Ca2+: simultaneous measurement of beat frequency and intracellular Ca2+
    • Lansley A.B., Sanderson M.J. Regulation of airway ciliary activity by Ca2+: simultaneous measurement of beat frequency and intracellular Ca2+. Biophys. J. 1999, 77:629-638.
    • (1999) Biophys. J. , vol.77 , pp. 629-638
    • Lansley, A.B.1    Sanderson, M.J.2
  • 22
    • 0026768788 scopus 로고
    • Control of the beat cycle of respiratory tract cilia by Ca2+ and cAMP
    • Lansley A.B., Sanderson M.J., Dirksen E.R. Control of the beat cycle of respiratory tract cilia by Ca2+ and cAMP. Am. J. Physiol. 1992, 263:L232-L242.
    • (1992) Am. J. Physiol. , vol.263
    • Lansley, A.B.1    Sanderson, M.J.2    Dirksen, E.R.3
  • 23
    • 11844267183 scopus 로고    scopus 로고
    • Phosphodiesterase-4 inhibitors for asthma and chronic obstructive pulmonary disease
    • Lipworth B.J. Phosphodiesterase-4 inhibitors for asthma and chronic obstructive pulmonary disease. Lancet 2005, 365:167-175.
    • (2005) Lancet , vol.365 , pp. 167-175
    • Lipworth, B.J.1
  • 24
    • 0029855117 scopus 로고    scopus 로고
    • Videomicroscopy of methacholine-induced contraction of individual airways in precision-cut lung slices
    • Martin C., Uhlig S., Ullrich V. Videomicroscopy of methacholine-induced contraction of individual airways in precision-cut lung slices. Eur. Respir. J. 1996, 9:2479-2487.
    • (1996) Eur. Respir. J. , vol.9 , pp. 2479-2487
    • Martin, C.1    Uhlig, S.2    Ullrich, V.3
  • 25
    • 0034988651 scopus 로고    scopus 로고
    • Differential effects of UTP, ATP, and adenosine on ciliary activity of human nasal epithelial cells
    • Morse D.M., Smullen J.L., Davis C.W. Differential effects of UTP, ATP, and adenosine on ciliary activity of human nasal epithelial cells. Am. J. Physiol. Cell Physiol. 2001, 280:C1485-C1497.
    • (2001) Am. J. Physiol. Cell Physiol. , vol.280
    • Morse, D.M.1    Smullen, J.L.2    Davis, C.W.3
  • 26
    • 69149095164 scopus 로고    scopus 로고
    • Phosphodiesterase-4 inhibition in COPD
    • O'Byrne P.M., Gauvreau G. Phosphodiesterase-4 inhibition in COPD. Lancet 2009, 374:665-667.
    • (2009) Lancet , vol.374 , pp. 665-667
    • O'Byrne, P.M.1    Gauvreau, G.2
  • 27
    • 0020501931 scopus 로고
    • Tracheobronchial airway structure as revealed by casting techniques
    • Phalen R.F., Oldham M.J. Tracheobronchial airway structure as revealed by casting techniques. Am. Rev. Respir. Dis. 1983, 128:S1-S4.
    • (1983) Am. Rev. Respir. Dis. , vol.128
    • Phalen, R.F.1    Oldham, M.J.2
  • 28
    • 23744451716 scopus 로고    scopus 로고
    • Roflumilast-an oral anti-inflammatory treatment for chronic obstructive pulmonary disease: a randomised controlled trial
    • Rabe K.F., Bateman E.D., O'Donnell D., Witte S., Bredenbroker D., Bethke T.D. Roflumilast-an oral anti-inflammatory treatment for chronic obstructive pulmonary disease: a randomised controlled trial. Lancet 2005, 366:563-571.
    • (2005) Lancet , vol.366 , pp. 563-571
    • Rabe, K.F.1    Bateman, E.D.2    O'Donnell, D.3    Witte, S.4    Bredenbroker, D.5    Bethke, T.D.6
  • 31
    • 33947367829 scopus 로고    scopus 로고
    • Regulation of mammalian ciliary beating
    • Salathe M. Regulation of mammalian ciliary beating. Annu. Rev. Physiol. 2007, 69:401-422.
    • (2007) Annu. Rev. Physiol. , vol.69 , pp. 401-422
    • Salathe, M.1
  • 32
    • 0033231444 scopus 로고    scopus 로고
    • Mode of Ca2+ action on ciliary beat frequency in single ovine airway epithelial cells
    • Salathe M., Bookman R.J. Mode of Ca2+ action on ciliary beat frequency in single ovine airway epithelial cells. J. Physiol. 1999, 520(Pt 3):851-865.
    • (1999) J. Physiol. , vol.520 , Issue.PART 3 , pp. 851-865
    • Salathe, M.1    Bookman, R.J.2
  • 33
    • 0016365668 scopus 로고
    • Tracheal mucous velocity in normal man and patients with obstructive lung disease: effects of terbutaline
    • Santa C.R., Landa J., Hirsch J., Sackner M.A. Tracheal mucous velocity in normal man and patients with obstructive lung disease: effects of terbutaline. Am. Rev. Respir. Dis. 1974, 109:458-463.
    • (1974) Am. Rev. Respir. Dis. , vol.109 , pp. 458-463
    • Santa, C.R.1    Landa, J.2    Hirsch, J.3    Sackner, M.A.4
  • 35
    • 0023431730 scopus 로고
    • The distribution and surface ultrastructure of airway epithelial cells in the rat lung: a scanning electron microscopic study
    • Souma T. The distribution and surface ultrastructure of airway epithelial cells in the rat lung: a scanning electron microscopic study. Arch. Histol. Jpn. 1987, 50:419-436.
    • (1987) Arch. Histol. Jpn. , vol.50 , pp. 419-436
    • Souma, T.1
  • 36
    • 0031914520 scopus 로고    scopus 로고
    • Phosphodiesterase isozymes: molecular targets for novel antiasthma agents
    • Torphy T.J. Phosphodiesterase isozymes: molecular targets for novel antiasthma agents. Am. J. Respir. Crit. Care Med. 1998, 157:351-370.
    • (1998) Am. J. Respir. Crit. Care Med. , vol.157 , pp. 351-370
    • Torphy, T.J.1
  • 37
    • 0030207033 scopus 로고    scopus 로고
    • Mucolytic and mucokinetic therapy
    • Wills P.J., Cole P.J. Mucolytic and mucokinetic therapy. Pulm. Pharmacol. 1996, 9:197-204.
    • (1996) Pulm. Pharmacol. , vol.9 , pp. 197-204
    • Wills, P.J.1    Cole, P.J.2
  • 40
    • 33745911590 scopus 로고    scopus 로고
    • Inhibition of airway hyperresponsiveness and pulmonary inflammation by roflumilast and other PDE4 inhibitors
    • Wollin L., Bundschuh D.S., Wohlsen A., Marx D., Beume R. Inhibition of airway hyperresponsiveness and pulmonary inflammation by roflumilast and other PDE4 inhibitors. Pulm. Pharmacol. Ther. 2006, 19:343-352.
    • (2006) Pulm. Pharmacol. Ther. , vol.19 , pp. 343-352
    • Wollin, L.1    Bundschuh, D.S.2    Wohlsen, A.3    Marx, D.4    Beume, R.5
  • 41
    • 0018728405 scopus 로고
    • Anatomic models of the tracheobronchial and pulmonary regions of the rat
    • Yeh H.C., Schum G.M., Duggan M.J. Anatomic models of the tracheobronchial and pulmonary regions of the rat. Anat. Rec. 1979, 195:483-492.
    • (1979) Anat. Rec. , vol.195 , pp. 483-492
    • Yeh, H.C.1    Schum, G.M.2    Duggan, M.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.