Paradoxical potentiation of exercise hyperpnea in congestive heart failure contradicts sherrington chemoreflex model and supports a respiratory optimization model

Advances in Experimental Medicine and Biology

Volumn 669, Issue , 2010, Pages 69-72

  Tin, Chung ^a   Wasserman, Karlman ^b   Cherniack, Neil S ^c   Poon, Chi Sang ^a  

^a Massachusetts Institute of Technology   (United States)

^b HARBOR UCLA MEDICAL CENTER   (United States)

^c RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANALYTICAL PARAMETERS; ARTERIAL CARBON DIOXIDE TENSION; BREATHING MECHANICS; CONFERENCE PAPER; CONGESTIVE HEART FAILURE; CONTROLLED STUDY; EXERCISE; EXERCISE TOLERANCE; HUMAN; HYPERCAPNIA; HYPERPNEA; INSPIRATORY CAPACITY; LUNG ALVEOLUS CARBON DIOXIDE TENSION; LUNG DEAD SPACE; LUNG GAS EXCHANGE; LUNG VOLUME; PRIORITY JOURNAL; PROCESS OPTIMIZATION; RESPIRATION CONTROL; RESPIRATORY AIRFLOW; RESPIRATORY FUNCTION; SHERRINGTON CHEMOREFLEX MODEL; TIDAL VOLUME; ARTICLE; BIOLOGICAL MODEL; BREATHING; HEART FAILURE; PATHOPHYSIOLOGY;

EXERCISE; HEART FAILURE; HUMANS; MODELS, BIOLOGICAL; RESPIRATION; RESPIRATORY DEAD SPACE;

EID: 77952296901     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4419-5692-7_15     Document Type: Conference Paper

References (6)

1. Johnson, R.L., Jr. (2001) Gas exchange efficiency in congestive heart failure II. Circulation 103(7), 916-918.
2. Poon, C.S. (1983) Optimal control of ventilation in hypoxia, hypercapnia and exercise. In B.J. Whipp and D.W. Wiberg (Eds.), Modelling and control of breathing (pp. 189-196). New York: Elsevier.
3. Poon, C.S. (2001) Possible mechanism of augmented exercise hyperpnea in congestive heart failure. Circulation 104(22), E131.
4. Poon, C.S., Lin, S.L., et al. (1992) Optimization character of inspiratory neural drive. J. Appl. Physiol. 72(5), 2005-2017.
5. Poon, C.S., Tin, C., et al. (2007) Homeostasis of exercise hyperpnea and optimal sensorimotor integration: The internal model paradigm. Respir. Physiol. Neurobiol. 159(1), 1-13; discussion 14-20. (Pubitemid 47451862)
6. Wasserman, K., Hansen, J.E., et al. (2005) Principles of exercise testing and interpretation. Philadelphia, PA: Lippincott Williams & Wilkins.