Prostate-regenerating capacity of cultured human adult prostate epithelial cells

Cells Tissues Organs

Volumn 191, Issue 3, 2010, Pages 203-212

  Yao, M ^a   Taylor, R A ^b   Richards, M G ^b   Sved, P ^a   Wong, J ^a   Eisinger, D ^a   Xie, C ^a   Salomon, R ^a   Risbridger, G P ^b   Dong, Q ^a,c  

^a ROYAL PRINCE ALFRED HOSPITAL   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Adult; Prostate; Stem cell differentiation; Stem cell research; Stromal cells; Tissue culture; Urology

Indexed keywords

ALDEHYDE DEHYDROGENASE; CD133 ANTIGEN; ANDROSTANOLONE; GLYCOPROTEIN; LEUKOCYTE ANTIGEN; PEPTIDE;

ARTICLE; CANCER PATIENT; CELL CULTURE; CELL DIFFERENTIATION; CELL ISOLATION; CONTROLLED STUDY; ENZYME ACTIVITY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INFORMED CONSENT; PRIORITY JOURNAL; PROSTATE EPITHELIUM; PROSTATE HYPERTROPHY; STEM CELL; STROMA CELL; TISSUE CULTURE; TISSUE REGENERATION; ADULT; ADULT STEM CELL; BIOSYNTHESIS; CELL LINEAGE; CELL SEPARATION; CHEMISTRY; COCULTURE; CULTURE MEDIUM; CYTOLOGY; EPITHELIUM CELL; MALE; METABOLISM; METHODOLOGY; ORGAN CULTURE TECHNIQUE; PHYSIOLOGY; PROSTATE; REGENERATION;

ADULT; ADULT STEM CELLS; ALDEHYDE DEHYDROGENASE; ANTIGENS, CD; CELL DIFFERENTIATION; CELL LINEAGE; CELL SEPARATION; CELLS, CULTURED; COCULTURE TECHNIQUES; CULTURE MEDIA; DIHYDROTESTOSTERONE; EPITHELIAL CELLS; GLYCOPROTEINS; HUMANS; MALE; ORGAN CULTURE TECHNIQUES; PEPTIDES; PROSTATE; REGENERATION; STROMAL CELLS;

EID: 77952293814     PISSN: 14226405     EISSN: None     Source Type: Journal    
DOI: 10.1159/000240244     Document Type: Article

References (22)

1. Barclay, W.W., L.S. Axanova, W. Chen, L. Romero, S.L. Maund, S. Soker, C.J. Lees, S.D. Cramer (2008) Characterization of adult prostatic progenitor/stem cells exhibiting self-renewal and multilineage differentiation. Stem Cells 26: 600-610.
2. Betschinger, J., K. Mechtler, J. Knoblich (2006) Asymmetric segregation of the tumor suppressor brat regulates self-renewal in drosophila neural stem cells. Cell 124: 1241-1253.
3. Collins, A.T., P.A. Berry, C. Hyde, M.J. Stower, N.J. Maitland (2005) Prospective identification of tumorigenic prostate cancer stem cells. Cancer Res 65: 10946-10951.
4. 1-integrin expression. J Cell Sci 114: 3865-3872.
5. Corti, S., F. Locatelli, D. Papadimitriou, C. Donadoni, R. Del Bo, M. Crimi, A. Bordoni, F. Fortunato, S. Strazzer, G. Menozzi, S. Salani, N. Bresolin, G.P. Comi (2006) Transplanted ALDHhiSSClo neural stem cells generate motor neurons and delay disease progression of nmd mice, an animal model of SMARD1. Hum Mol Genet 15: 167-187.
6. Gudjonsson, T., M.K. Magnusson (2005) Stem cell biology and the cellular pathways of carcinogenesis. APMIS 113: 922-929.
7. Hess, D.A., T.E. Meyerrose, L. Wirthlin, T.P. Craft, P.E. Herrbrich, M.H. Creer, J.A. Nolta (2004) Functional characterization of highly purified human hematopoietic repopulating cells isolated according to aldehyde dehydrogenase activity. Blood 104: 1648-1655.
8. Hudson, D.L., M. O'Hare, F.M. Watt, J.R. Masters (2000) Proliferative heterogeneity in the human prostate: evidence for epithelial stem cells. Lab Invest 80: 1243-1250.
9. Isaacs, J.T., D.S. Coffey (1989) Etiology and disease process of benign prostatic hyperplasia. Prostate 2(suppl): 33-50.
10. Jones, R.J., J.P. Barber, M.S. Vala, M.I. Collector, S.H. Kaufmann, S.M. Ludeman, O.M. Colvin, J. Hilton (1995) Assessment of aldehyde dehydrogenase in viable cells. Blood 85: 2742-2746.
11. Kim, C.F., E.L. Jackson, A.E. Woolfenden, S. Lawrence, I. Babar, S. Vogel, D. Crowley, R.T. Bronson, T. Jacks (2005) Identification of bronchioalveolar stem cells in normal lung and lung cancer. Cell 121: 823-835.
12. Leong, K.G., B.E. Wang, L. Johnson, W.Q. Gao, K.G. Leong, B.-E. Wang, L. Johnson, W.-Q. Gao (2008) Generation of a prostate from a single adult stem cell. Nature 456: 804-808.
13. Litvinov, I.V., D.J. Vander Griend, Y. Xu, L. Antony, S.L. Dalrymple, J.T. Isaacs (2006) Low-calcium serum-free defined medium selects for growth of normal prostatic epithelial stem cells. Cancer Res 66: 8598-8607.
14. Miki, J., B. Furusato, H. Li, Y. Gu, H. Takahashi, S. Egawa, I.A. Sesterhenn, D.G. McLeod, S. Srivastava, J.S. Rhim (2007) Identification of putative stem cell markers, CD133 and CXCR4, in hTERT-immortalized primary nonmalignant and malignant tumor-derived human prostate epithelial cell lines and in prostate cancer specimens. Cancer Res 67: 3153-3161.
15. Miki, J., J.S. Rhim (2008) Prostate cell cultures as in vitro models for the study of normal stem cells and cancer stem cells. Prostate Cancer Prostatic Dis 11: 32-39.
16. Peehl, D.M. (2005) Primary cell cultures as models of prostate cancer development. Endocr Relat Cancer 12: 19-47.
17. Peehl, D.M., T.A. Stamey (1986) Serum-free growth of adult human prostatic epithelial cells. In Vitro Cell Dev Biol 22: 82-90.
18. Pileri, S.A., G. Roncador, C. Ceccarelli, M. Piccioli, A. Briskomatis, E. Sabattini, S. Ascani, D. Santini, P.P. Piccaluga, O. Leone, S. Damiani, C. Ercolessi, F. Sandri, F. Pieri, L. Leoncini, B. Falini (1997) Antigen retrieval techniques in immunohistochemistry: comparison of different methods. J Pathol 183: 116-123.
19. Richardson, G.D., C.N. Robson, S.H. Lang, D.E. Neal, N.J. Maitland, A.T. Collins (2004) CD133, a novel marker for human prostatic epithelial stem cells. J Cell Sci 117: 3539-3545.
20. Roth, C.C., C.H. Bell, B. Woodson, A.D. Schultz, B.W. Palmer, D. Frimberger, K.M. Fung, H. K. Lin, B.P. Kropp, C.C. Roth, C.H. Bell, B. Woodson, A.D. Schultz, B.W. Palmer, D. Frimberger, K.-M. Fung, H.-K. Lin, B.P. Kropp (2009) Temporal differentiation and maturation of regenerated rat urothelium. BJU Int 103: 836-841.
21. Storms, R.W., P.D. Green, K.M. Safford, D. Niedzwiecki, C.R. Cogle, O.M. Colvin, N.J. Chao, H.E. Rice, C.A. Smith (2005) Distinct hematopoietic progenitor compartments are delineated by the expression of aldehyde dehydrogenase and CD34. Blood 106: 95-102.
22. Xin, L., H. Ide, Y. Kim, P. Dubey, O.N. Witte (2003) In vivo regeneration of murine prostate from dissociated cell populations of postnatal epithelia and urogenital sinus mesenchyme. Proc Natl Acad Sci USA 100(suppl 1): 11896-11903.