A prospective study of the impact of subthreshold mixed states on the 24-month clinical outcomes of bipolar I disorder or schizoaffective disorder

Journal of Affective Disorders

Volumn 124, Issue 1-2, 2010, Pages 22-28

  Dodd, S ^a   Kulkarni, J ^b   Berk, L ^a   Ng, F ^a   Fitzgerald, P B ^b   de Castella, A R ^b   Filia, S ^b   Filia, K ^b   Montgomery, W ^c   Kelin, K ^c   Smith, M ^d   Brnabic, A ^c   Berk, M ^a,e,f  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c ELI LILLY AUSTRALIA PTY LTD   (Australia)

^d UNIVERSITY OF WESTERN SYDNEY   (Australia)

^e THE NATIONAL CENTRE OF EXCELLENCE IN YOUTH MENTAL HEALTH   (Australia)

^f FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH   (Australia)

Author keywords

Bipolar disorder; Mixed states; Outcomes; Schizoaffective disorder

Indexed keywords

ADULT; AGED; ARTICLE; BIPOLAR I DISORDER; CLINICAL FEATURE; COMPARATIVE STUDY; CONTROLLED STUDY; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DISEASE ASSOCIATION; FEMALE; HEALTH; HUMAN; HYPOMANIA; INTERVIEW; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; MANIA; MENTAL HEALTH; MIXED MANIA AND DEPRESSION; OBSERVATIONAL STUDY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUALITY OF LIFE; SCHIZOAFFECTIVE PSYCHOSIS; SYMPTOMATOLOGY; TREATMENT OUTCOME;

ADULT; BIPOLAR DISORDER; COMORBIDITY; DEPRESSIVE DISORDER, MAJOR; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; PSYCHOTIC DISORDERS; QUALITY OF LIFE;

EID: 77952293216     PISSN: 01650327     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jad.2009.10.027     Document Type: Article

References (27)

1. Akiskal H.S., Hantouche E.G., Bourgeois M.L., Azorin J.M., Sechter D., Allilaire J.F., Lancrenon S., Fraud J.P., and Chatenet-Duchene L. Gender, temperament, and the clinical picture in dysphoric mixed mania: findings from a French national study (EPIMAN). J. Affect. Disord. 50 (1998) 175-186
2. Akiskal H.S., Benazzi F., Perugi G., and Rihmer Z. Agitated "unipolar" depression re-conceptualized as a depressive mixed state: implications for the antidepressant-suicide controversy. J. Affect. Disord. 85 (2005) 245-258
3. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 4th Edition (2000), American Psychiatric Association, Washington, DC Text Revised
4. Balázs J., Benazzi F., Rihmer Z., Rihmer A., Akiskal K.K., and Akiskal H.S. The close link between suicide attempts and mixed (bipolar) depression: implications for suicide prevention. J. Affect. Disord. 91 (2006) 133-138
5. Benazzi F. Which could be a clinically useful definition of depressive mixed state?. Prog. Neuropsychopharmacol. Biol. Psychiatry 26 (2002) 1105-1111
6. Benazzi F. Bipolar II depressive mixed state: finding a useful definition. Compr. Psychiatry 44 (2003) 21-27
7. Benazzi F., and Akiskal H.S. Psychometric delineation of the most discriminant symptoms of depressive mixed states. Psychiatry Res. 141 (2006) 81-88
8. Berk M., Dodd S., Callaly P., Berk L., Fitzgerald P., de Castella A.R., Filia S., Filia K., Tahtalian S., Biffin F., Kelin K., Smith M., Montgomery W., and Kulkarni J. History of illness prior to a diagnosis of bipolar disorder or schizoaffective disorder. J. Affect. Disord. 103 1-3 (2007) 181-186
9. Cassidy F., and Carroll B.J. The clinical epidemiology of pure and mixed manic episodes. Bipolar. Disord. 3 (2001) 35-40
10. Cassidy F., Ahearn E., Murry E., Forest K., and Carroll B.J. Diagnostic depressive symptoms of the mixed bipolar episode. Psychol. Med. 30 (2000) 403-411
11. Dilsaver S.C., Swann A.C., Shoaib A.M., Bowers T.C., and Halle M.T. Depressive mania associated with nonresponse to antimanic agents. Am. J. Psychiatry 150 (1993) 1548-1551
12. Dilsaver S.C., Chen Y.W., Swann A.C., Shoaib A.M., and Krajewski K.J. Suicidality in patients with pure and depressive mania. Am. J. Psychiatry 151 (1994) 1312-1315
13. Dilsaver S.C., Benazzi F., Rihmer Z., Akiskal K.K., and Akiskal H.S. Gender, suicidality and bipolar mixed states in adolescents. J. Affect. Disord. 87 (2005) 11-16
14. First M.B., Spitzer R.L., Gibbon M., and Williams J.B.W. Structured Clinical Interview for Axis I DSM-IV Disorders - Patient Version (SCID-I/P) (1994), New York State Psychiatric Institute Biometrics Research, New York
15. Hantouche E.G., Akiskal H.S., Azorin J.M., Châtenet-Duchêne L., and Lancrenon S. Clinical and psychometric characterization of depression in mixed mania: a report from the French National Cohort of 1090 manic patients. J. Affect. Disord. 96 (2006) 225-232
16. Henry C., M'Bailara K., Desage A., Gard S., Misdrahi D., and Vieta E. Towards a reconceptualization of mixed states, based on an emotional-reactivity dimensional model. J. Affect. Disord. 101 (2007) 35-41
17. Keller M.B., Lavori P.W., Coryell W., Endicott J., and Mueller T.I. Bipolar I: a five-year prospective follow-up. J. Nerv. Ment. Dis. 181 (1993) 238-245
18. Khalsa H.M., Salvatore P., Hennen J., Baethge C., Tohen M., and Baldessarini R.J. Suicidal events and accidents in 216 first-episode bipolar I disorder patients: predictive factors. J. Affect. Disord. 106 1-2 (2008) 179-184
19. Koukopoulos A. Agitated depression as a mixed state and the problem of melancholia. Psychiatr. Clin. North Am. 22 (1999) 547-564
20. Kulkarni J., Berk M., Fitzgerald P.B., de Castella A.R., Montgomery W., Kelin K., Brnabic A., Granger R.E., and Dodd S. The Bipolar Comprehensive Outcomes Study (BCOS): baseline findings of an Australian cohort study. J. Affect. Disord. 107 (2008) 135-144
21. Minnai G.P., Tondo L., Salis P., Ghiani C., Manfredi A., Paluello M.M., Baethge C., and Baldessarini R.J. Secular trends in first hospitalizations for major mood disorders with comorbid substance use. Int. J. Neuropsychopharmacol. 9 (2006) 319-326
22. Perugi G., Akiskal H.S., Micheli C., Toni C., and Madaro D. Clinical characterization of depressive mixed state in bipolar-I patients: Pisa-San Diego collaboration. J. Affect. Disord. 67 (2001) 105-114
23. Prien R.F., Himmelhoch J.M., and Kupfer D.J. Treatment of mixed mania. J. Affect. Disord. 15 (1988) 9-15
24. Röttig D., Röttig S., Brieger P., and Marneros A. Temperament and personality in bipolar I patients with and without mixed episodes. J. Affect. Disord. 104 (2007) 97-102
25. Secunda S.K., Swann A., Katz M.M., Koslow S.H., Croughan J., and Chang S. Diagnosis and treatment of mixed mania. Am. J. Psychiatry 144 (1987) 96-98
26. Suppes T., Mintz J., McElroy S.L., Altshuler L.L., Kupka R.W., Frye M.A., Keck Jr. P.E., Nolen W.A., Leverich G.S., Grunze H., Rush A.J., and Post R.M. Mixed hypomania in 908 patients with bipolar disorder evaluated prospectively in the Stanley Foundation Bipolar Treatment Network: a sex-specific phenomenon. Arch. Gen. Psychiatry 62 (2005) 1089-1096
27. Vieta E. The treatment of mixed states and the risk of switching to depression. Eur. Psychiatr. 20 (2005) 96-100