Diagnostic value of procalcitonin, interleukin 8, interleukin 6, and c-reactive protein for detecting bacteremia and fungemia in cancer patients;Valor diagnóstico de la procalcitonina, la interleucina 8, la interleucina 6 y la proteína C reactiva en la deteccin de bacteriemia y fungemia en pacientes con cáncer

Enfermedades Infecciosas y Microbiologia Clinica

Volumn 28, Issue 5, 2010, Pages 273-277

  Aznar Oroval, Eduardo ^a   Sánchez Yepes, Marina ^a   Lorente Alegre, Pablo ^a   San Juan Gadea, Mari Carmen ^a   Ortiz Muñoz, Blanca ^a   Prez Ballestero, Pilar ^a   Picn Roig, Isabel ^a   Maquez Richart, Joaquín ^a  

^a Instituto Valenciano de Oncologa   (Spain)

Author keywords

Bacteremia; C reactive protein; Cancer; Procalcitonin

Indexed keywords

BIOLOGICAL MARKER; C REACTIVE PROTEIN; INTERLEUKIN 6; INTERLEUKIN 8; PROCALCITONIN; CALCITONIN; PROTEIN PRECURSOR;

ADULT; ARTICLE; BACTEREMIA; BACTERIUM DETECTION; CANCER CHEMOTHERAPY; CANCER PATIENT; CANCER RADIOTHERAPY; CANCER SURGERY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC PROCEDURE; DIAGNOSTIC VALUE; DISEASE TRANSMISSION; FEMALE; FEVER; FUNGEMIA; FUNGUS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HOSPITAL INFECTION; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIMODALITY CANCER THERAPY; NEUTROPENIA; SENSITIVITY AND SPECIFICITY; AGED; BLOOD; COMPLICATION; MIDDLE AGED; NEOPLASM; PROSPECTIVE STUDY; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; BACTEREMIA; C-REACTIVE PROTEIN; CALCITONIN; FEMALE; FUNGEMIA; HUMANS; INTERLEUKIN-6; INTERLEUKIN-8; MALE; MIDDLE AGED; NEOPLASMS; PROSPECTIVE STUDIES; PROTEIN PRECURSORS;

EID: 77952287140     PISSN: 0213005X     EISSN: 15781852     Source Type: Journal    
DOI: 10.1016/j.eimc.2009.08.001     Document Type: Article

References (29)

1. P.A. Pizzo Managament of fever in patients with cancer and treatment induced neutropenia N Engl J Med 328 1993 1323 1332
2. a Edicicin.(3a). Hemocultivos 2003. En: Procedimientos en Microbiologa Clnica. Recomendaciones de la Sociedad Espaola de Enfermedades Infecciosas y Microbiologa Clnica. Editores: Cercenado E y Cantn R. [consultado: 4/2009]. Disponible en: http://www.seimc.org/protocolos/microbiologia
3. H. Wisplinghoff, T. Bischoff, S.M. Tallent, H. Seifert, R.P. Wenzel, and M.B. Edmond Nosocomial bloodstream infections in US hospitals:analysis of 24174 cases from a prospective nationwide surveillance study Clin Infect Dis 39 2004 309 317
4. H. Wisplinghoff, H. Seifert, R.P. Wenzel, and M.B. Edmond Current trends in the epidemiology of nosocomial bloodstream infections in patients with haematological malignancies and solid neoplasms in hospitals in the United States Clin Infect Dis 36 2003 1103 1110
5. J.M. Cisneros-Herreros, J. Cobo-Reinoso, M. Pujol-Rojo, J. Rodrguez-Bano, and M. Salavert-Lleti Gua para el diagnóstico y tratamiento del paciente con bacteriemia. Guas de la SEIMC Enferm Infecc Microbiol Clin 25 2007 111 130
6. G.P. Bodey, M. Buckley, Y.S. Sathe, and E.J. Freireich Quantitative relationships between circulating leukocytes and infection in patients with acute leukemia Ann Intern Med 64 1966 328 340
7. A.C. Fluit1, J.T. van der Bruggen, F.M. Aarestrup, J. Verhoef1, and W.T.M. Jansen Priorities for antibiotic resistance surveillance in Europe Clin Microbiol Infect 12 2006 410 417
8. Kristinsson KG, Monnet DL. Increasing multidrug resistance and limited treatment options: Situation and initiatives in Europe Euro Surveill. 2008;13:pii=19043.
9. P. Dandona, D. Nix, M.F. Wilson, A. Aljada, J. Love, and M. Assicot Procalcitonin increase after endotoxin infection in normal subjets J Clin Endocrinol Metab 93 1994 54 58
10. T. Kishimoto The biology of interleukin-6 Blood 74 1989 1 10
11. D. Rennick, S. Hudak, G. Yang, and J. Jacson Regulation of hemopoietic cell development by interleukins 4, 5 and 6 Immunology Research 8 1989 215 225
12. J.J. Oppenheim, C.O. Zachariac, N. Mukaida, and K. Matsushima Properties of the novel proinflammatory supergene "intercrin" cytokine family Annual Review of Immunology 9 1991 617 648
13. P. Torrabadella de Reynoso, and H. Prez-Molt La protena C reactiva en los tiempos de la medicina molecular Med Clin 125 2005 775 777
14. W.J. John, K.A. Foon, and R.A. Patchell Paraneoplastic sndromes V.T. De Jr S. Hellman, S.A. Rosenberg, Cancer. Principles & Practice of Oncology 1997 Lippincott-Raven publishers Philadelphia 2397 2422
15. a Edicin.
16. L. Marti, C. Cervera, X. Filalla, J.L. Marin, M. Almela, and J.M. Gatell Respuesta inflamatoria en pacientes ancianos con bacteriemia Enferm Infecc Microbiol Clin 26 2008 146 149
17. K. Reinhart, M. Meisner, and F.M. Brunkhorts Markers for sepsisDiagnosis: What is useful? Crit Care Clin 22 2006 503 519
18. H. Aalto, A. Takala, H. Kautiainen, and H. Repo Laboratory markers of systemic inflammation as predictors of bloodstream infection in acutely ill patients admitted to hospital in medical emergency Eur J Clin Microbiol Infect Dis 23 2004 699 704
19. E.S. De Bont, E. Vellenga, J.C. Swaanenburg, V. Fidler, P.J. Visser-van Brummen, and W.A. Kamps Plasma IL-8 and IL-6 levels can be used to define a group with low risk of septicaemia among cancer patients with fever and neutropenia British Journal of Haematology 107 1999 75 80
20. P. Fraunberger, Y. Wang, E. Holler, K.G. Parhofer, D. ngel, and A.K. Walli Prognostic value of interleukin 6, procalcitonin, and C reactive protein levels in intensive care unit patients during first increase of fever Shock 26-1 2006 10 12
21. G. Fleischhack, I. Kambeck, D. Capic, C. Hasan, and U. Bode Procalcitonin in paediatric cancer patients: Its diagnostic relevance is superior to that of C-reactive protein, interleukin 6, interleukin 8, soluble interleukin 2 receptor and soluble tumour necrosis factor receptor II Br J Haematol 111 2000 1093 1102
22. Bernard L, Ferriere F, Casassus P, Malas F, Lvêque S, Guillevin L, Lortholary O. Procalcitonin as an early marker of bacterial infection in severely neutropenic febrile adults. Clin Infect Dis 1998; 27: 9145.
23. A. Engel, G. Steinbach, P. Kern, and W.V. Kern Diagnostic value of procalcitonin serum levels in neutropenic patients with fever: comparison with interleukin-8 Scandinavian Journal of Infectious Diseases 31 1999 185 189
24. B.M.P. Tang, G.D. Eslik, J.C. Craig, and A.S. Malean Accuracy of procalcitonin for sepsis diagnosis in critically ill patients: Systematic review and meta-analysis Lancet Infect Dis 7 2007 210 217
25. A.E. Jones, J.F. Fiechtl, M.D. Brown, J.J. Ballew, and J.A. Kline Procalcitonin test in the diagnosis of bacteremia: A meta-analysis Ann of Emerg Med 50 2007 34 41
26. M.T. Sandri, R. Passerini, M.E. Leon, F.A. Peccatori, L. Zorrino, and M. Salvatici Procalcitonin as a useful marker of infection in hemato-oncological patients with fever Anticancer Res 28 2008 3061 3065
27. A. Uys, B.L. Rapoport, and R. Anderson Febrile neutropenia: A prospective study to validate the Multinational Association of Supportive Care of Cancer (MASCC) risk-index score Support Care Cancer 12 2004 555 560
28. J. Klastersky, L. Ameye, J. Maertens, A. Georgala, F. Muanza, and M. Aoun Bacteraemia in febrile neutropenic cancer patients Int J Antimicrob Agents 30 2007 S51 S59
29. B.H. David Improved diagnostic approaches to infection/sepsis detection Expert Rev Mol Diagn 5 2005 193 207