The effect of 2,5-hexanedione on permeability of blood-nerve barrier in rats

Human and Experimental Toxicology

Volumn 29, Issue 6, 2010, Pages 497-506

  Liu, Qingjun ^a   Duan, Huawei ^a   Dai, Yufei ^a   Niu, Yong ^a   Chen, Hong ^a   Liu, Qiing ^a   Bin, Ping ^a   Zheng, Yuxin ^a  

^a CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

Author keywords

25 hexanedione; Blood nerve barrier; Neuropathy; Permeability

Indexed keywords

ACETONYLACETONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD NERVE BARRIER; BODY WEIGHT; CONTROLLED STUDY; FEMORAL VEIN; FLUORESCENCE ANALYSIS; GAIT; HISTOPATHOLOGY; MALE; NERVE FIBER DEGENERATION; NONHUMAN; PERIPHERAL NERVE INJURY; PERIPHERAL NEUROPATHY; PERMEABILITY; POPLITEAL VEIN; PRIORITY JOURNAL; RAT; SCIATIC NERVE; WEIGHT CHANGE; WEIGHT REDUCTION;

ANIMALS; BLOOD-NERVE BARRIER; BODY WEIGHT; DISEASE MODELS, ANIMAL; EVANS BLUE; FLUORESCENT DYES; GAIT; HEXANES; HEXANONES; MALE; ORGAN SPECIFICITY; PERIPHERAL NERVOUS SYSTEM AGENTS; PERIPHERAL NERVOUS SYSTEM DISEASES; PERMEABILITY; RANDOM ALLOCATION; RATS; RATS, WISTAR; SCIATIC NERVE; SEVERITY OF ILLNESS INDEX; TIBIAL NERVE; TIME FACTORS;

ANIMALIA; RATTUS; RATTUS NORVEGICUS;

EID: 77952284683     PISSN: 09603271     EISSN: 14770903     Source Type: Journal    
DOI: 10.1177/0960327109357213     Document Type: Article

References (47)

1. Hadden RD, Gregson NA, Gold R., Smith KJ and Hughes RA Accumulation of immunoglobulin across the ĝ€blood-nerve barrier in spinal roots in adoptive transfer experimental autoimmune neuritis. Neuropathol Appl Neurobiol 2002 ; 28: 489-497.
2. Komoly S. Experimental demyelination caused by primary oligodendrocyte dystrophy. Regional distribution of the lesions in the nervous system of mice [corrected]. Ideggyogy Sz 2005 ; 58: 40-43.
3. Wessig C., Jestaedt L., Sereda MW, Bendszus M. and Stoll G. Gadofluorine M-enhanced magnetic resonance nerve imaging: comparison between acute inflammatory and chronic degenerative demyelination in rats. Exp Neurol 2008 ; 210: 137-143.
4. Boddingius J. Ultrastructural and histophysiological studies on the blood-nerve barrier and perineurial barrier in leprosy neuropathy. Acta Neuropathol 1984 ; 64: 282-296.
5. Seitz RJ, Neuen-Jacob E., Wechsler W. Significance of lymphocytes and blood vessel changes for edema formation in polyradiculoneuritis. Acta Neuropathol 1988 ; 76: 564-573.
6. Giannini C., Dyck PJ Ultrastructural morphometric abnormalities of sural nerve endoneurial microvessels in diabetes mellitus. Ann Neurol 1994 ; 36: 408-415.
7. Uncini A., Di Muzio A., Di Guglielmo G., et al. Effect of rhTNF-alpha injection into rat sciatic nerve. J Neuroimmunol 1999 ; 94: 88-94.
8. Kanda T., Numata Y., Mizusawa H. Chronic inflammatory demyelinating polyneuropathy: decreased claudin-5 and relocated ZO-1. J Neurol Neurosurg Psychiatry 2004 ; 75: 765-769.
9. Jakobsen J., Malmgren L., Olsson Y. Permeability of the blood-nerve barrier in the streptozotocin-diabetic rat. Exp Neurol 1978 ; 60: 277-285.
10. Rechthand E., Smith QR, Latker CH and Rapoport SI Altered blood-nerve barrier permeability to small molecules in experimental diabetes mellitus. J Neuropathol Exp Neurol 1987 ; 46: 302-314.
11. Bradbury MW, Lightman SL, Yuen L. and Pinter GG Permeability of blood-brain and blood-nerve barriers in experimental diabetes mellitus in the anaesthetized rat. Exp Physiol 1991 ; 76: 887-898.
12. Weerasuriya A., Curran GL, Poduslo JF Physiological changes in the sciatic nerve endoneurium of lead-intoxicated rats: a model of endoneurial homeostasis. Brain Res 1990 ; 517: 1-6.
13. Ohi T., Poduslo JF, Curran GL and Dyck PJ Quantitative method for detection of blood-nerve barrier alterations in experimental animal models of neuropathy. Exp Neurol 1985 ; 90: 365-372.
14. Bouldin TW, Earnhardt TS, Goines ND Restoration of blood-nerve barrier in neuropathy is associated with axonal regeneration and remyelination. J Neuropathol Exp Neurol 1991 ; 50: 719-728.
15. Southam E., Thomas PK, King RH, Goss-Sampson MA and Muller DP Experimental vitamin E deficiency in rats. Morphological and functional evidence of abnormal axonal transport secondary to free radical damage. Brain 1991 ; 114: 915-936.
16. Prineas J. Peripheral nerve changes in thiamine-deficient rats. An electron microscope study. Arch Neurol 1970 ; 23: 541-548.
17. Weerasuriya A., Curran GL, Poduslo J.F. Developmental changes in blood-nerve transfer of albumin and endoneurial albumin content in rat sciatic nerve. Brain Res 1990 ; 521: 40-46.
18. Schaumburg HH, Spencer PS Environmental hydrocarbons produce degeneration in cat hypothalamus and optic tract. Science 1978 ; 199: 199-200.
19. Couri D., Abdel-Rahman MS, Hetland LB Biotransformation of n-hexane and methyl n-butyl ketone in guinea pigs and mice. Am Ind Hyg Assoc J 1978 ; 39: 295-300.
20. Spencer PS, Schaumburg HH Ultrastructural studies of the dying-back process. IV. Differential vulnerability of PNS and CNS fibers in experimental central-peripheral distal axonopathies. J Neuropathol Exp Neurol 1977 ; 36: 300-320.
21. LoPachin RM, Ross JF, Reid ML, Das S., Mansukhani S. and Lehning EJ Neurological evaluation of toxic axonopathies in rats: acrylamide and 2,5-hexanedione. Neurotoxicology 2002 ; 23: 95-110.
22. LoPachin RM, DeCaprio AP Gamma-Diketone neuropathy: axon atrophy and the role of cytoskeletal protein adduction. Toxicol Appl Pharmacol 2004 ; 199: 20-34.
23. Saria A., Lundberg JM Evans blue fluorescence: quantitative and morphological evaluation of vascular permeability in animal tissues. J Neurosci Methods 1983 ; 8: 41-49.
24. Rizzuto N., Rizzuto N., De Grandis D., Di Trapani G. and Pasinato E. n-hexane polyneuropathy. An occupational disease of shoemakers. Eur Neurol 1980 ; 19: 308-315.
25. Herskowitz A., Ishii N., Schaumburg H. N-hexane neuropathy. A syndrome occurring as a result of industrial exposure. N Engl J Med 1971 ; 285: 82-85.
26. Graham DI, Adams JH, Nicoll JA, Maxwell WL and Gennarelli TA The nature, distribution and causes of traumatic brain injury. Brain Pathol 1995 ; 5: 397-406.
27. Spencer PS, and Schaumburg HH Recent morphological studies of toxic neuropathy. Dev Toxicol Environ Sci 1980 ; 8: 3-11.
28. Kurimoto N., Nan YS, Chen ZY, et al. Effects of specific signal transduction inhibitors on increased permeability across rat endothelial monolayers induced by neuropeptide Y or VEGF. Am J Physiol Heart Circ Physiol 2004 ; 287: H100-106.
29. Poduslo JF, Curran GL Increased permeability across the blood-nerve barrier of albumin glycated in vitro and in vivo from patients with diabetic polyneuropathy. Proc Natl Acad Sci U S A 1992 ; 89: 2218-2222.
30. Grover-Johnson N., Spencer PS Peripheral nerve abnormalities in aging rats. J Neuropathol Exp Neurol 1981 ; 40: 155-165.
31. Spies JM, Westland KW, Bonner JG and Pollard JD Intraneural activated T cells cause focal breakdown of the blood-nerve barrier. Brain 1995 ; 118: 857-868.
32. Pollard JD, Westland KW, Harvey GK, et al. Activated T cells of nonneural specificity open the blood-nerve barrier to circulating antibody. Ann Neurol 1995 ; 37: 467-475.
33. Rutledge JC, Curry FE, Blanche P. and Krauss RM Solvent drag of LDL across mammalian endothelial barriers with increased permeability. Am J Physiol 1995 ; 268: H1982-1991.
34. Hahn AF, Feasby TE, Gilbert JJ Blood-nerve barrier studies in experimental allergic neuritis. Acta Neuropathol 1985 ; 68: 101-109.
35. Inglis HR, Csurhes PA, McCombe PA Antibody responses to peptides of peripheral nerve myelin proteins P0 and P2 in patients with inflammatory demyelinating neuropathy. J Neurol Neurosurg Psychiatry 2007 ; 78: 419-422.
36. Kanda T., Yamawaki M., Mizusawa H. Sera from Guillain-Barre patients enhance leakage in blood-nerve barrier model. Neurology 2003 ; 60: 301-306.
37. Sparrow JR, Kiernan JA Endoneurial vascular permeability in degenerating and regenerating peripheral nerves. Acta Neuropathol 1981 ; 53: 181-188.
38. Omura K., Ohbayashi M., Sano M., Omura T., Hasegawa T. and Nagano A. The recovery of blood-nerve barrier in crush nerve injury-a quantitative analysis utilizing immunohistochemistry. Brain Res 2004 ; 1001: 13-21.
39. Hirakawa A., Takeyama N., Nakatani T. and Tanaka T. Mitochondrial permeability transition and cytochrome c release in ischemia-reperfusion injury of the rat liver. J Surg Res 2003 ; 111: 240-247.
40. Roux KJ, Amici SA, Fletcher BS and Notterpek L. Modulation of epithelial morphology, monolayer permeability, and cell migration by growth arrest specific 3/peripheral myelin protein 22. Mol Biol Cell 2005 ; 16: 1142-1151.
41. Roux F., Couraud PO Rat brain endothelial cell lines for the study of blood-brain barrier permeability and transport functions. Cell Mol Neurobiol 2005 ; 25: 41-580.
42. Saray A., Can B., Akbiyik F. and Askar I. Ischaemia-reperfusion injury of the peripheral nerve: an experimental study. Microsurgery 1999 ; 19: 374-380.
43. Nagamatsu M., Schmelzer JD, Zollman PJ, Smithson IL, Nickander KK and Low PA Ischemic reperfusion causes lipid peroxidation and fiber degeneration. Muscle Nerve 1996 ; 19: 37-47.
44. Neuen E., Seitz RJ, Langenbach M. and Wechsler W. The leakage of serum proteins across the blood-nerve barrier in hereditary and inflammatory neuropathies. An immunohistochemical and morphometric study. Acta Neuropathol 1987 ; 73: 53-61.
45. Weerasuriya A., Curran GL, Poduslo JF Blood-nerve transfer of albumin and its implications for the endoneurial microenvironment. Brain Res 1989 ; 494: 114-121.
46. Liu LY, Zheng H., Xiao HL, et al. Comparison of blood-nerve barrier disruption and matrix metalloprotease-9 expression in injured central and peripheral nerves in mice. Neurosci Lett 2008 ; 434: 155-159.
47. Shimizu F., Sano Y., Maeda T., et al. Peripheral nerve pericytes originating from the blood-nerve barrier expresses tight junctional molecules and transporters as barrier-forming cells. J Cell Physiol 2008 ; 217: 388-399.