Screening of a PKC ζ-specific kinase inhibitor PKCzI257.3 which inhibits EGF-induced breast cancer cell chemotaxis

Investigational New Drugs

Volumn 28, Issue 3, 2010, Pages 268-275

  Wu, Jing ^a   Zhang, Baogang ^a,b   Wu, Min ^a   Li, Hongyan ^a   Niu, Ruifang ^a   Ying, Guoguang ^a   Zhang, Ning ^a  

^a TIANJIN MEDICAL UNIVERSITY   (China)

^b WEIFANG MEDICAL UNIVERSITY   (China)

Author keywords

Breast cancer; Chemotaxis; EGFR; Metastasis; PKC ; PKCzI257.3

Indexed keywords

2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; COFILIN; EPIDERMAL GROWTH FACTOR; PKCZI 2573; PROTEIN KINASE C ZETA; PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG;

ACTIN POLYMERIZATION; ARTICLE; BREAST CANCER; CELL MIGRATION; CELL PROLIFERATION; CHEMOTAXIS; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SCREENING; DRUG STRUCTURE; HUMAN; HUMAN CELL; IC 50; METASTASIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ACTINS; BENZYLAMINES; BREAST NEOPLASMS; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; CELL SURVIVAL; CHEMOTAXIS; COFILIN 1; EPIDERMAL GROWTH FACTOR; FEMALE; HUMANS; PROTEIN KINASE C; PROTEIN KINASE INHIBITORS; PYRROLES;

EID: 77952242326     PISSN: 01676997     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10637-009-9242-8     Document Type: Article

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