Structural and stereochemical requirements of the spiroketal group of hippuristanol for antiproliferative activity

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 10, 2010, Pages 3112-3115

  Li, Wei ^a   Dang, Yongjun ^b   Liu, Jun O ^b   Yu, Biao ^a  

^a SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY   (China)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cancer; Eukaryotic translation initiation; Inhibitor

Indexed keywords

GAMMA BUTYROLACTONE; HIPPURISTANOL; HYDROCORTISONE; METHYL IODIDE; NATURAL PRODUCT; PANTOLACTONE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; EUKARYOTE; HELA CELL; HUMAN; HUMAN CELL; INHIBITION KINETICS; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; TRANSLATION INITIATION;

ANTINEOPLASTIC AGENTS; FURANS; HELA CELLS; HUMANS; SPIRO COMPOUNDS; STEREOISOMERISM; STEROLS; STRUCTURE-ACTIVITY RELATIONSHIP;

EUKARYOTA;

EID: 77952238051     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.03.093     Document Type: Article

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