Anticancer activities of curcumin on human hepatocarcinoma cell line Sk-hep-1

Zhongguo Zhongyao Zazhi

Volumn 35, Issue 4, 2010, Pages 485-488

  Wang, Weizhang ^a   Zhang, Biyu ^b   Chen, Hongyuan ^a   Zhang, Li ^a  

^a GUANGDONG PHARMACEUTICAL UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY   (China)

Author keywords

Apoptosis; Curcumin; Hepatocarcinoma cell line Sk hep 1; MDR1 gene

Indexed keywords

CURCUMIN; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1; PROTEIN BCL XL; SURVIVIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE; CELL PROLIFERATION; CONTROLLED STUDY; DOSE RESPONSE; GENE EXPRESSION REGULATION; GROWTH INHIBITION; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CURCUMIN; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS;

EID: 77952229523     PISSN: 10015302     EISSN: None     Source Type: Journal    
DOI: 10.4268/cjcmm20100417     Document Type: Article

References (15)

1. Sharma R A, Gescher A J, Steward W P. Curcumin: The story so far [J]. Eur J Cancer, 2005, 41(13): 1955.
2. Karunagaran D, Rashmi R, Kumar T R. Induction of apoptosis by curcumin and its implications for cancer therapy [J]. Curr Cancer Drug Targets, 2005, 5(2): 117. (Pubitemid 40488598)
3. 2/M arrest sensitizes curcumin-resistant hepatoma cells to apoptosis [J]. FEBS Lett, 2008, 582(18): 2689.
4. Jiang M C, Yang Yen H F, Lin J K, et al. Differential regulation of p53, c-Myc, Bcl-2 and Bax protein expression during apoptosis induced by widely divergent stimuli in human hepatoblastoma cells [J]. Oncogene, 1996, 13(3): 609.
5. Chuang S E, Kuo M L, Hsu C H, et al. Curcumin-containing diet inhibits diethylnitrosamine-induced murine hepatocarcinogenesis [J]. Carcinogenesis, 2000, 21(2): 331.
6. Anthony V, Skach W R. Molecular mechanism of P-glycoprotein assembly into cellular membranes [J]. Curr Protein Pept Sci, 2002, 3(5): 485.
7. Anuchapreeda S, Leechanachai P, Smith M M, et al. Modulation of P-glycoprotein expression and function by curcumin in multidrug-resistant human KB cells [J]. Biochem Pharmacol, 2002, 64(4): 573.
8. Ganta S, Amiji M. Coadministration of paclitaxel and curcumin in nanoemulsion formulations to overcome multidrug resistance in tumor cells [J]. Mol Pharm, 2009, 6(3): 928.
9. Anuchapreeda S, Thanarattanakom P, Sittipreechacharn S, et al. Inhibitory effect of curcumin on MDR1 gene expression in patient leukemic cells [J]. Arch Pharm Res, 2006, 29(10): 866.
10. Wahl H, Tan L, Griffith K, et al. Curcumin enhances Apo2L/TRAIL-induced apoptosis in chemoresistant ovarian cancer cells [J]. Gynecol Oncol, 2007, 105(1): 104.
11. Nakano A, Watanabe N, Nishizaki Y, et al. Immunohistochemical studies on the expression of P-glycoprotein and p53 in relation to histological differentiation and cell proliferation in hepatocellular carcinoma [J]. Hepatol Res, 2003, 25(2): 158. (Pubitemid 36416665)