Salmonella-mediated delivery of RNase P-based ribozymes for inhibition of viral gene expression and replication in human cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 16, 2010, Pages 7269-7274

  Bai, Yong ^a   Li, Hongjian ^a   Vu, Gia Phong ^a   Gong, Hao ^a   Umamoto, Sean ^a   Zhou, Tianhong ^a   Lu, Sangwei ^a   Liu, Fenyong ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Antisense; Antiviral; Gene delivery; Gene targeting; RNA cleavage

Indexed keywords

ANTIVIRUS AGENT; ASSEMBLIN; CAPSID PROTEIN; COMPLEMENTARY DNA; NUCLEIC ACID; RIBONUCLEASE P; RIBOZYME; RNASE P RIBOZYME; SCAFFOLD PROTEIN; UNCLASSIFIED DRUG; VIRUS VECTOR;

ANTIVIRAL ACTIVITY; ARTICLE; CELL SPECIFICITY; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; GENE CONSTRUCT; GENE DELIVERY SYSTEM; GENE EXPRESSION; GENE TARGETING; GENE TRANSFER; HUMAN; HUMAN CYTOMEGALOVIRUS; HUMAN TISSUE; MACROPHAGE; NONHUMAN; PRIORITY JOURNAL; RNA CLEAVAGE; SALMONELLA; SEQUENCE ANALYSIS; TISSUE SPECIFICITY; VIROGENESIS; VIRUS ASSEMBLY; VIRUS INHIBITION; VIRUS REPLICATION;

CELL DIFFERENTIATION; CYTOMEGALOVIRUS INFECTIONS; FIBROBLASTS; GENE EXPRESSION REGULATION, VIRAL; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HUMANS; KINETICS; NUCLEIC ACID CONFORMATION; POINT MUTATION; RIBONUCLEASE P; RNA, CATALYTIC; SALMONELLA; VIRUS REPLICATION;

HUMAN HERPESVIRUS 5; MIRIDAE; SALMONELLA;

EID: 77952218796     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0912813107     Document Type: Article

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