Antidepressants work, sort of-our system of care does not

Journal of Clinical Psychopharmacology

Volumn 30, Issue 2, 2010, Pages 101-104

  Pies, Ronald ^a,b  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SUNY UPSTATE MEDICAL UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDEPRESSANT AGENT; CITALOPRAM; IMIPRAMINE; PAROXETINE; PLACEBO;

CLINICAL RESEARCH; CLINICAL TRIAL; DEPRESSION; DISEASE DURATION; DRUG EFFICACY; DRUG INDICATION; DRUG RESPONSE; DRUG SAFETY; EDITORIAL; EVIDENCE BASED MEDICINE; GENETIC HETEROGENEITY; HAMILTON SCALE; HEALTH CARE SYSTEM; HUMAN; MAJOR DEPRESSION; MEDICAL PRACTICE; PRIORITY JOURNAL; PSYCHOPHARMACOLOGY; PSYCHOTHERAPY; REMISSION;

ANTIDEPRESSIVE AGENTS; DELIVERY OF HEALTH CARE; DEPRESSIVE DISORDER; HUMANS; PSYCHOTHERAPY; RANDOMIZED CONTROLLED TRIALS AS TOPIC;

EID: 77952202952     PISSN: 02710749     EISSN: None     Source Type: Journal    
DOI: 10.1097/JCP.0b013e3181d52dea     Document Type: Editorial

References (28)

1. Kirsch I, Deacon BJ, Huedo-Medina TB, et al. Initial severity and antidepressant benefits: a meta-analysis of data submitted to the Food and Drug Administration [published online February 26, 2008]. PLoS Med.2008;5(2):e45.
2. Fournier JC, DeRubeis RJ, Hollon SD, et al. Antidepressant drug effects and depression severity: a patient-level meta-analysis. JAMA. 2010;303(1):47-53.
3. Gever J. Antidepressants less effective when depression is mild. Medpage Today. January 5, 2010. Available at: http://www.medpagetoday.com/Psychiatry/ Depression/17797. Accessed January 18, 2010.
4. Friedman RA. Before you quit antidepressants. New York Times. January 11, 2010. Available at: http://www.nytimes.com/2010/01/12/health/12mind.html? partner=rss&emc=rss. Accessed January 18, 2010.
5. Kobak KA, Kane JM, Thase ME, et al. Why do clinical trials fail? The problem of measurement error in. clinical trials: time to test new paradigms? J Clin Psychopharmacol. 2007;27:1-5.
6. Walsh BT, Seidman SN, Sysko R, et al. Placebo response in studies of major depression: variable, substantial, and growing. JAMA. 2002;287:1840-1847. (Pubitemid 34303629)
7. Rush AJ, Trivedi MH, Wisniewski SR, et al. Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR*D report. Am J Psychiatry. 2006;163: 1905-1917.
8. Preskorn SH. Outpatient Management of Depression. 3rd ed. Caddo, OK: Professional Communications, Inc; 2009.
9. Pies RW. Pseudoresistant bipolar depression. J Clin Psychiatry. 2009;70:1476.
10. Ghaemi SN. Why you cannot believe your eyes. Psychiatric Times. September 5, 2009;26(9). Available at: http://www.psychiatrictimes. com/display/article/ 10168/1444255. Accessed January 14, 2010.
11. Turner EH, Matthews AM, Linardatos E, et al. Selective publication of antidepressant trials and its influence on apparent efficacy. N Engl J Med. 2008;358:252-260.
12. Ghaemi SN. Why antidepressants are not antidepressants: STEP-D, STAR*D, and the return of neurotic depression. Bipolar Disord. 2008;10:957-968.
13. Laje G, Perus RH, Rush AJ, et al. Pharmacogenetics studies in STAR*D: strengths, limitations, and results. Psychiatr Serv, 2009; 60(11):1446-1457.
14. Pies RW. Depression and the pitfalls of causality: implications for DSM-V J Affect Disord. 2009;116(1-2):1-3.
15. Kendler KS, Myers J, Zisook S. Does bereavement-related major depression differ from major depression associated with other stressful life events? Am J Psychiatry. 2008;165(11):1449-1455.
16. Ferguson JM. SSRI antidepressant medications: adverse effects and tolerability. J Clin Psychiatry. 2001;3(1):22-27. (Pubitemid 33807486)
17. Kaplan A. Whither melancholia? Psychiatric Times. January 8, 2010; 27:15-16. Available at: http://www.psychiatrictimes.com/display/article/10168/ 1508125. Accessed January 18, 2010.
18. Brown WA. Treatment response in melancholia. Acta Psychiatr Scand Suppl. 2007;433:125-129.
19. Luty SE, Carter JD, McKenzie JM, et al. Randomized controlled trial, of interpersonal, psychotherapy and cognitive behavioural therapy for depression. Br J Psychiatry. 2007;190:496-502. (Pubitemid 46868833)
20. Driessen E, Cuijpers P, de Maat SC, et al. The efficacy of short-term, psychodynamic psychotherapy for depression: a meta-analysis. Clin Psychol Rev. 2010;30(1):25-36.
21. Baker TB, McFall RM, Shoham V Current status and future prospects of clinical psychology: toward a scientifically principled approach to mental and behavioral health care. Psychol Sci Public Interest. 2009;9(2):67-103. Available at: http://www.psychologicalscience.org/journals/pspi/inpress/baker.pdf. Accessed January 13, 2010.
22. Olfson M, Marcus SC. National patterns in antidepressant medication treatment. Arch Gen Psychiatry. 2009;66:848-856.
23. Mojtabai R, Olfson. M. National trends in psychotherapy by office-based psychiatrists. Arch Gen Psychiatry. 2008;65:962-970.
24. Akiskal HS, Benazzi F, Perugi G, et al. Agitated "unipolar" depression re-conceptualized as a depressive mixed state: implications for the antidepressant-suicide controversy. J Affect Disord. 2005; 85(3):245-258. (Pubitemid 40386508)
25. González HM, Vega WA, Williams DR, et al. Depression care in the United States: too little for too few. Arch Gen Psychiatry. 2010;67(1):37-46.
26. Wang SS. Studies: mental ills are often overtreated, undertreated. Wall Street Journal. January 5, 2010. Available at: http://online. wsj.com/article/SB 10001424052748703580904574638750777038042. html. Accessed. January 18, 2010.
27. Shader RI. The cart before the horse? Health insurance reform before health, care reform [editorial]. J Clin Psychopharmacol. 2009;29: 413-414.
28. DeRubeis RJ, Fournier JC. Critiquing a critique (letter). Health Science, New York Times. January 18, 2010. Available at: http://www.nytimes. com/2010/01/19/science/19lett-CRITIQUINGAC-LETTERS.html? ref=health/. Accessed January 20, 2010.