Pharmacokinetics of epirubicin hydrochloride long-circulating thermosensitive liposomes in rat plasma

Yaoxue Xuebao

Volumn 45, Issue 3, 2010, Pages 365-370

  Wu, Yan ^a   Zhang, Fu Cheng ^a   Wu, Cheng ^b   Mei, Xing Guo ^c   Lü, Wan Liang ^d  

^a AIR FORCE GENERAL HOSPITAL   (China)

^b General Hospital of the Second Artillery   (China)

^c BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

^d PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Epirubicin hydrochloride; Long circulating; Pharmacokinetic; Thermosensitive liposome

Indexed keywords

DAUNORUBICIN; EPIRUBICIN; FORMIC ACID; LIPOSOME; METHANOL;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; DRUG DISTRIBUTION; DRUG ELIMINATION; HEAT SENSITIVITY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; PLASMA; RAT;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; AREA UNDER CURVE; CHROMATOGRAPHY, LIQUID; DRUG CARRIERS; EPIRUBICIN; LIPOSOMES; MALE; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

EID: 77952175846     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Minotti G, Menna P, Salvatorelli E. Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity [J]. Pharmacol Rev, 2004, 56: 185-229. (Pubitemid 38720829)
2. Zhang YD, Ding C, Zhang ZJ, et al. Preparation of epirubicin polybutycyanocrylate nanoparticles with optimized process [J]. Chin J Exp Surg 2006, 23: 1191-1193.
3. Tai LA, Tsai PJ, Wang YC, et al. Thermosensitive liposomes entrapping iron oxide nanoparticles for controllable drug release [J]. Nanotechnology, 2009, 20: 135101.
4. Puri A, Kramer-Marek G, Campbell-Massa R, et al. HER2-specific affibody-conjugated thermosensitive liposomes (Affisomes) for improved delivery of anticancer agents [J]. J Liposome Res, 2008, 18: 293-307.
5. Wang Z, Chen T, Wang RT, et al. Preparation and thermosensitivity behavior of polymer liposomes made of poly(2-ethylacrylic acid) alkylamide derivatives [J]. Acta Pharm Sin 2008, 43: 1239-1244.
6. Qi XW, Mei XG. In vitro of release property carboplatin thermo-sensitive liposome [J]. Chin Pharm J 2009, 44: 40-42.
7. Huang GH, Zhu XL, Zhang N, et al. Preparation of lomusitine thermosensitive liposomes and investigation of anti-tumor activity in vitro [J]. Chin Pharm J 2007, 42: 914-918. (Pubitemid 47066189)
8. Wu Y, Wu C, Kang YM, et al. Preparation and quality control of epirubicin hydrochloride liposomes [J]. Bull Acad Mil Med Sci 2008, 32: 165-167.
9. Wang Y, Sheng LS, Zhang ZX, et al. Determination of related substances in epirubicin by using LC/ESI/MS [J]. J Pharm Anal 2001, 21: 392-393.
10. Xiong W, Jiang XH, Zhang D. The pharmacokinetic comparison of hydrochloric doxorubicin injections and hydrochloric doxorubicin liposomes in rats [J]. West Chin Pharm J 2004, 19: 97-99.
11. Fan J, Wen X, Miu YS. Study on pharmacokinetics and tissue distribution of free doxorubicin in rats [J]. J Chin Pharm Univ 2001, 32: 354-358.
12. Wilma W, Mating JG, Hendriks G. Determination of epirubicin and its metabolite epirubicinol in saliva and plasma by HPLC [J]. Ther Drug Monit, 2003, 25: 433-440. (Pubitemid 36927973)
13. Wang XH. Determination of pharmorubicin in human plasma using high-performance liquid chromatography [J]. Ant Inf Pharm 2005, 2: 89-90.
14. Robert D, Jeanine E, Robert M. Quantification of doxorubicin and metabolites in rat plasma and small volume tissue samples by liquid chromatography/electrospray tandem mass spectroscopy [J]. J Chromatogr B, 2004, 808: 141-152.