Structural and pharmacological characterization of the crotamine isoforms III-4 (MYX4_CROCu) and III-7 (MYX7_CROCu) isolated from the Crotalus durissus cumanensis venom

Toxicon

Volumn 55, Issue 8, 2010, Pages 1443-1452

  Ponce Soto, Luis Alberto ^a   Martins de Souza, Daniel ^a,b   Marangoni, Sergio ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

Author keywords

Crotalus durissus cumanensis; Crotamine; Myotoxin and mass spectrometry; Myotoxin HPLC; Neurotoxin " ex vivo"

Indexed keywords

CREATINE KINASE; CROTAMINE; CROTAMINE III 4; CROTAMINE III 7; CYSTEINE; INTERLEUKIN 6; SNAKE VENOM; UNCLASSIFIED DRUG;

ALKYLATION; AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHICKEN; CONTROLLED STUDY; CREATINE KINASE BLOOD LEVEL; CROTALUS DURISSUS; CYTOTOXICITY; HYDROLYSIS; INFLAMMATION; ION EXCHANGE CHROMATOGRAPHY; MALE; MOLECULAR WEIGHT; MOUSE; MYOBLAST; MYOTUBE; NEUROMUSCULAR TRANSMISSION; NEUROTOXICITY; NONHUMAN; PAW EDEMA; PRIORITY JOURNAL; PROTEIN PURIFICATION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SNAKE; STRUCTURE ANALYSIS; TANDEM MASS SPECTROMETRY; TOXIN ANALYSIS; TOXIN STRUCTURE;

ANIMALS; CHICKENS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CROTALID VENOMS; CROTALUS; EDEMA; HYDROLYSIS; MALE; MICE; MUSCLE CONTRACTION; NEUROMUSCULAR JUNCTION; NEUROTOXINS; PEPTIDE FRAGMENTS; PEPTIDE MAPPING; PROTEIN ISOFORMS; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, PROTEIN; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TRYPSIN;

CROTALUS DURISSUS CUMANENSIS; CROTALUS DURISSUS TERRIFICUS;

EID: 77952145074     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2010.02.024     Document Type: Article

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