Crotamine inhibits preferentially fast-twitching muscles but is inactive on sodium channels

Toxicon

Volumn 50, Issue 4, 2007, Pages 553-562

  Rizzi, Carina T ^a,b   Carvalho de Souza, João Luís ^b   Schiavon, Emanuele ^c   Cassola, Antônio Carlos ^b   Wanke, Enzo ^c   Troncone, Lanfranco R P ^a  

^a INSTITUTO BUTANTAN   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c UNIVERSITY OF MILANO BICOCCA   (Italy)

Author keywords

Behavior; Crotalus durissus terrificus; Crotamine; Muscle; Sodium channels; Toxin

Indexed keywords

ALPHA POMPILIDOTOXIN; BETA POMPILIDOTOXIN; CROTAMINE; SEA ANEMONE TOXIN; SNAKE VENOM; SODIUM CHANNEL; SODIUM CHANNEL BLOCKING AGENT; SPIDER VENOM; TETRODOTOXIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; ELECTROSTIMULATION; EXTENSOR DIGITORUM LONGUS MUSCLE; FAST MUSCLE; HINDLIMB; HYPOTHESIS; MALE; MOUSE; MUSCLE EXCITATION; NONHUMAN; PARALYSIS; PATCH CLAMP; PRIORITY JOURNAL; RAT; SLOW MUSCLE; SNAKE; SOLEUS MUSCLE; SPINAL GANGLION; TOXICITY TESTING; TOXIN ANALYSIS;

ANIMALS; CROTALID VENOMS; DOSE-RESPONSE RELATIONSHIP, DRUG; GANGLIA, SPINAL; MALE; MICE; MUSCLE CONTRACTION; RATS; RATS, WISTAR; SODIUM CHANNELS;

ACTINIARIA; ARANEAE; CROTALUS DURISSUS TERRIFICUS; RATTUS;

EID: 34548454942     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2007.04.026     Document Type: Article

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