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Volumn 878, Issue 19, 2010, Pages 1513-1518
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Quantification of CLR1401, a novel alkylphosphocholine anticancer agent, in rat plasma by hydrophilic interaction liquid chromatography-tandem mass spectrometric detection
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Author keywords
Alkyl phosphocholine; CLR1401; Hydrophilic interaction chromatography; LC MS MS; Liquid liquid extraction
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Indexed keywords
96-WELL FORMAT;
ANALYSIS TIME;
ANTI-CANCER AGENTS;
BIOANALYTICAL METHODS;
DRUG CANDIDATES;
ETHYL ACETATES;
GRADIENT ELUTION;
HIGH CONCENTRATION;
HYDROPHILIC INTERACTION CHROMATOGRAPHY;
HYDROPHILIC INTERACTION LIQUID CHROMATOGRAPHIES;
INTRAVENOUS ADMINISTRATION;
LC-MS/MS;
LIQUID-LIQUID EXTRACTION;
METHOD VALIDATIONS;
OCTADECYL;
PHOSPHOCHOLINE;
PLASMA SAMPLES;
RAT PLASMA;
RELATIVE ERRORS;
RELATIVE STANDARD DEVIATIONS;
SAMPLE ANALYSIS;
SILICA COLUMN;
TANDEM MASS SPECTROMETRIC DETECTION;
TOXICOKINETICS;
ALKYLATION;
COLUMN CHROMATOGRAPHY;
CUSTOMER SATISFACTION;
ESTERS;
HYDROCARBONS;
HYDROPHILICITY;
LIQUIDS;
PLASMA (HUMAN);
QUALITY CONTROL;
SILICA;
SOLVENT EXTRACTION;
TOTAL QUALITY MANAGEMENT;
LIQUID CHROMATOGRAPHY;
18 (4 IODOPHENYL)OCTADECYL PHOSPHOCHOLINE;
ACETIC ACID ETHYL ESTER;
ANTINEOPLASTIC AGENT;
CLR 1404;
UNCLASSIFIED DRUG;
ACCURACY;
ANALYTICAL ERROR;
ANIMAL EXPERIMENT;
ARTICLE;
BLOOD ANALYSIS;
CONTROLLED STUDY;
DRUG DETERMINATION;
DRUG ELIMINATION;
ELUTION;
FLOW RATE;
HYDROPHILIC INTERACTION CHROMATOGRAPHY;
LIQUID LIQUID EXTRACTION;
NONHUMAN;
PLASMA CONCENTRATION-TIME CURVE;
PRIORITY JOURNAL;
QUALITY CONTROL;
QUANTITATIVE ANALYSIS;
RAT;
SENSITIVITY AND SPECIFICITY;
TANDEM MASS SPECTROMETRY;
TOXICOKINETICS;
VALIDATION PROCESS;
ANIMALS;
ANTINEOPLASTIC AGENTS;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
DRUG STABILITY;
HYDROPHOBICITY;
LEAST-SQUARES ANALYSIS;
PHOSPHORYLCHOLINE;
RATS;
REPRODUCIBILITY OF RESULTS;
SENSITIVITY AND SPECIFICITY;
TANDEM MASS SPECTROMETRY;
RATTUS;
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EID: 77952109190
PISSN: 15700232
EISSN: None
Source Type: Journal
DOI: 10.1016/j.jchromb.2010.04.002 Document Type: Article |
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Times cited : (8)
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References (18)
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