Attenuated Bordetella pertussis vaccine strain BPZE1 modulates allergen-induced immunity and prevents allergic pulmonary pathology in a murine model

Clinical and Experimental Allergy

Volumn 40, Issue 6, 2010, Pages 933-941

  Kavanagh, H ^a   Noone, C ^a   Cahill, E ^a   English, K ^a   Locht, C ^b   Mahon, B P ^a  

^a NATIONAL UNIVERSITY OF IRELAND   (Ireland)

^b INSTITUT PASTEUR DE LILLE   (France)

Author keywords

Asthma; Bordetella pertussis; Vaccine; Whooping cough

Indexed keywords

GAMMA INTERFERON; IMMUNOGLOBULIN E; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; LIVE VACCINE; OVALBUMIN; PERTUSSIS VACCINE; ALLERGEN;

ALLERGIC DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY SPECIFICITY; ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BORDETELLA PERTUSSIS; CONTROLLED STUDY; DISEASE EXACERBATION; FEMALE; HELPER CELL; IMMUNITY; IMMUNOMODULATION; IMMUNOSTIMULATION; LUNG DISEASE; LUNG LAVAGE; MOUSE; NONHUMAN; PERTUSSIS; PRIORITY JOURNAL; RESPIRATORY TRACT INFLAMMATION; SENSITIZATION; ANIMAL; BAGG ALBINO MOUSE; DISEASE MODEL; HUMAN; HYPERSENSITIVITY, IMMEDIATE; IMMUNOLOGY; INFLAMMATION; LUNG; PATHOGENICITY; PATHOLOGY; VIRULENCE; WHOOPING COUGH;

ALLERGENS; ANIMALS; BORDETELLA PERTUSSIS; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; HYPERSENSITIVITY, IMMEDIATE; INFLAMMATION; LUNG; MICE; MICE, INBRED BALB C; OVALBUMIN; PERTUSSIS VACCINE; VACCINES, ATTENUATED; VIRULENCE; WHOOPING COUGH;

EID: 77952080082     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2010.03459.x     Document Type: Article

References (43)

1. Romagnani S. Immunologic influences on allergy and the TH1/TH2 balance. J Allergy Clin Immunol 2004 113 : 395 400.
2. Postma DS, Bleecker BE, Amelung PJ et al. Genetic susceptibility to asthma-bronchial hyperresponsiveness coinherited with a major gene for atopy. N Engl J Med 1995 333 : 894 900.
3. Holgate ST, Davies DE, Lackie PM, Wilson SJ, Puddicombe SM, Lordan JL. Epithelial-mesenchymal interactions in the pathogenesis of asthma. J Allergy Clin Immunol 2000 105 : 193 204.
4. Del Prete G, Maggi E, Parronchi P et al. IL-4 is an essential factor for the IgE synthesis induced in vitro by human T cell clones and their supernatants. J Immunol 1988 140 : 4193 4198.
5. Wilder JA, Collie DD, Wilson BS, Bice DE, Lyons CR, Lipscomb MF. Dissociation of airway hyperresponsiveness from immunoglobulin E and airway eosinophilia in a murine model of allergic asthma. Am J Respir Cell Mol Biol 1999 20 : 1326 1334. (Pubitemid 129503252)
6. Schleimer RP, Sterbinsky SA, Kaiser J et al. IL-4 induces adherence of human eosinophils and basophils but not neutrophils to endothelium. Association with expression of VCAM-1. J Immunol 1992 148 : 1086 1092.
7. Walsh GM, Wardlaw AJ, Hartnell A, Sanderson CJ, Kay AB. IL-5 enhances the in vitro adhesion of human eosinophils, but not neutrophils, in a leucocyte integrin (CD11/18)-dependent manner. Immunology 1990 71 : 258 265. (Pubitemid 20341227)
8. Romagnani S. Human TH1 and TH2 subsets: regulation of differentiation and role in protection and immunopathology. Int Arch Allergy Immunol 1992 98 : 279 285.
9. Johnson TR, Graham BS. Secreted respiratory syncytial virus G glycoprotein induces interleukin-5 (IL-5), IL-13, and eosinophilia by an IL-4-independent mechanism. J Virol 1999 73 : 8485 8489.
10. Matsuse H, Behera AK, Kumar M, Rabb H, Lockey RF, Mohapatra SS. Recurrent respiratory syncytial virus infections in allergen-sensitized mice lead to persistent airway inflammation and hyperresponsiveness. J Immunol 2000 164 : 6583 6592. (Pubitemid 30408845)
11. Harju TH, Leinonen M, Nokso-Koivisto J et al. Pathogenic bacteria and viruses in induced sputum or pharyngeal secretions of adults with stable asthma. Thorax 2006 61 : 579 584. (Pubitemid 44035137)
12. Ennis DP, Cassidy JP, Mahon BP. Prior Bordetella pertussis infection modulates allergen priming and the severity of airway pathology in a murine model of allergic asthma. Clin Exp Allergy 2004 34 : 1488 1497.
13. Mills KH, Brady M, Ryan E, Mahon BP. A respiratory challenge model for infection with Bordetella pertussis: application in the assessment of pertussis vaccine potency and in defining the mechanism of protective immunity. Dev Biol Stand 1998 95 : 31 41.
14. Ryan EJ, Nilsson L, Kjellman N, Gothefors L, Mills KH. Booster immunization of children with an acellular pertussis vaccine enhances Th2 cytokine production and serum IgE responses against pertussis toxin but not against common allergens. Clin Exp Immunol 2000 121 : 193 200. (Pubitemid 30659755)
15. Nilsson L, Grüber C, Granström M, Björkstén B, Kjellman NI. Pertussis IgE and atopic disease. Allergy 1998 53 : 1195 1201. (Pubitemid 29037993)
16. Ennis DP, Cassidy JP, Mahon BP. Acellular pertussis vaccine protects against exacerbation of allergic asthma due to Bordetella pertussis in a murine model. Clin Diagn Lab Immunol 2005 12 : 409 417. (Pubitemid 41175336)
17. Ennis DP, Cassidy JP, Mahon BP. Whole cell pertussis vaccine protects against exacerbation of allergic asthma. Immunol Lett 2005 97 : 91 100.
18. Mielcarek N, Debrie AS, Raze D et al. Live attenuated B. pertussis as a single-dose nasal vaccine against whooping cough. PLoS Pathog 2006 2 : 1662 1670. (Pubitemid 44147419)
19. Mascart F, Verscheure V, Malfroot A et al. Bordetella pertussis infection in 2-month-old infants promotes type 1 T cell responses. J Immunol 2003 170 : 1504 1509. (Pubitemid 36139521)
20. Menozzi FD, Mutombo R, Renauld G et al. Heparin-inhibitable lectin activity of the filamentous hemagglutinin adhesin of Bordetella pertussis. Infect Immun 1994 62 : 769 778. (Pubitemid 24065554)
21. Mills KH, Ryan M, Ryan E, Mahon BP. A murine model in which protection correlates with pertussis vaccine efficacy in children reveals complementary roles for humoral and cell-mediated immunity in protection against Bordetella pertussis. Infect Immun 1997 66 : 594 602. (Pubitemid 28074200)
22. Barnard A, Mahon BP, Watkins J, Redhead K, Mills KHG. Th1/Th2 cell dichotomy in acquired immunity to Bordetella pertussis: variables in the in vivo priming and in vitro cytokine detection techniques affect the classification of T cell subsets as Th1, Th2 or Th0. Immunology 1996 87 : 372 380. (Pubitemid 126424011)
23. Mahon BP, Sheahan BJ, Griffin F, Murphy G, Mills KHG. Atypical disease after Bordetella pertussis respiratory infection of mice with targeted disruptions of interferon-γ receptor or immunoglobulin μ chain genes. J Exp Med 1997 186 : 1843 1851. (Pubitemid 27524594)
24. Morokata T, Ishikawa J, Ida K, Yamada T. C57BL/6 mice are more susceptible to antigen-induced pulmonary eosinophilia than BALB/c mice, irrespective of systemic T helper 1/T helper 2 responses. Immunology 1999 98 : 345 351. (Pubitemid 29526955)
25. Strachan D. Hay fever, hygiene and household size. Br Med J 1989 299 : 1259 1260. (Pubitemid 19280051)
26. Skerry CM, Cassidy JP, English K, Feunou-Feunou P, Locht C, Mahon BP. A live attenuated Bordetella pertussis candidate vaccine does not cause disseminating infection in IFN-γ receptor knockout mice. Clin Vaccine Immunol 2009 16 : 1344 1351.
27. Grüber C, Warner J, Hill D, Bauchau V EPAAC Study Group. Early atopic disease and early childhood immunization - is there a link? Allergy 2008 63 : 1464 1472.
28. Martignon G, Oryszczyn MP, Annesi-Maesano I. Does childhood immunization against infectious diseases protect from the development of atopic disease? Pediatr Allergy Immunol 2005 16 : 193 200. (Pubitemid 40638046)
29. Peebles RS Jr., Hashimoto K, Collins RD et al. Immune interaction between respiratory syncytial virus infection and allergen sensitization critically depends on timing of challenges. J Infect Dis 2001 184 : 1374 1379. (Pubitemid 33108850)
30. Holgate S, Casale T, Wenzel S, Bousquet J, Deniz Y, Reisner C. The anti-inflammatory effects of omalizumab confirm the central role of IgE in allergic inflammation. J Allergy Clin Immunol 2005 115 : 459 465. (Pubitemid 40341694)
31. Hamelmann E, Tadeda K, Oshiba A, Gelfand EW. Role of IgE in the development of allergic airway inflammation and airway hyperresponsiveness - a murine model. Allergy 1999 54 : 297 305. (Pubitemid 29232384)
32. Sur S, Wild JS, Choudhury BK, Sur N, Alam R, Klinman DM. Long term prevention of allergic lung inflammation in a mouse model of asthma by CpG oligodeoxynucleotides. J Immunol 1999 162 : 6284 6293. (Pubitemid 29314994)
33. Richter A, Puddicombe SM, Lordan JL, Bucchieri F, Wilson SJ. The contribution of interleukin (IL)-4 and IL-13 to the epithelial-mesenchymal trophic unit in asthma. Am J Respir Cell Mol Biol 2001 25 : 385 391. (Pubitemid 32918922)
34. Cohn L, Herrick C, Niu N, Homer R, Bottomly K. IL-4 promotes airway eosinophilia by suppressing IFN-γ production: defining a novel role for IFN-γ in the regulation of allergic airway inflammation. J Immunol 2001 166 : 2760 2767. (Pubitemid 32175128)
35. Wen FQ, Kohyama T, Liu X et al. Interleukin-4- and interleukin-13- enhanced transforming growth factor-beta2 production in cultured human bronchial epithelial cells is attenuated by interferon-gamma. Am J Respir Cell Mol Biol 2002 26 : 484 490. (Pubitemid 34253933)
36. Gleich G. Mechanisms of eosinophil-associated inflammation. J Allergy Clin Immunol 2000 105 : 651 663. (Pubitemid 30226437)
37. Brusselle GG, Kips JC, Tavernier JH et al. Attenuation of allergic airway inflammation in IL-4 deficient mice. Clin Exp Allergy 1994 24 : 73 80.
38. Wills-Karp M, Luyimbazi J, Xu X, Schofield B, Neben TY, Karp CL. Interleukin-13: central mediator of allergic asthma. Science 1998 282 : 2258 2261. (Pubitemid 29004074)
39. Belcher C, Drenkow J, Kehoe B et al. The transcriptional responses of respiratory epithelial cells to Bordetella pertussis reveal host defensive and pathogen counter-defensive strategies. Proc Natl Acad Sci 2000 97 : 13847 13852.
40. Das P. Whooping cough makes global comeback. Lancet Infect Dis 2002 2 : 322.
41. Hansen G, Berry G, DeKruyff RH, Umetsu DT. Allergen-specific Th1 cells fail to counterbalance Th2 cell-induced airway hyperreactivity but cause severe airway inflammation. J Clin Invest 1999 103 : 175 183. (Pubitemid 29053135)
42. Marsland BJ, Scanga CB, Kopf M, Le Gros G. Allergic airway inflammation is exacerbated during acute influenza infection and correlates with increased allergen presentation and recruitment of allergen-specific T-helper type 2 cells. Clin Exp Allergy 2004 34 : 1299 1306. (Pubitemid 39093072)
43. Gern J. Viral and bacterial infections in the development and progression of asthma. J Allergy Clin Immunol 2000 105 (Part 2) : S497 502. (Pubitemid 30109015)